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  1. Article

    Open Access

    Sex differences in the association of long-term exposure to heat stress on kidney function in a large Taiwanese population study

    The incidence and prevalence of dialysis in Taiwan are high compared to other regions. Consequently, mitigating chronic kidney disease (CKD) and the worsening of kidney function have emerged as critical health...

    Yi-Kong Chen, **-Hsun Wu, Pei-Yu Wu, Yi-Chun Tsai, Yi-Wen Chiu in Scientific Reports (2024)

  2. Article

    Open Access

    The prognostic value of URR equals that of Kt/V for all-cause mortality in Taiwan after 10-year follow-up

    Kt/V and URR (urea reduction ratio) measurements represent dialysis adequacy. Single-pool Kt/V is theoretically a superior method and is recommended by the Kidney Disease Outcomes Quality Initiative guidelines...

    Yi-Kong Chen, Chih-Sheng Chu, Sheng-Wen Niu, Hugo You-Hsien Lin in Scientific Reports (2023)

  3. Article

    Open Access

    PKD2 founder mutation is the most common mutation of polycystic kidney disease in Taiwan

    Autosomal Dominant polycystic kidney disease (ADPKD) is the most common inherited adult kidney disease. Although ADPKD is primarily caused by PKD1 and PKD2, the identification of several novel causative genes in ...

    Chih-Chuan Yu, An-Fu Lee, Stefen Kohl, Ming-Yen Lin, Siao Muk Cheng in npj Genomic Medicine (2022)

  4. Article

    Correction to: APASL clinical practice guideline on hepatitis B reactivation related to the use of immunosuppressive therapy

    George Lau, Ming-Lung Yu, Grace Wong, Alexander Thompson in Hepatology International (2022)

  5. Article

    APASL clinical practice guideline on hepatitis B reactivation related to the use of immunosuppressive therapy

    Hepatitis B reactivation related to the use of immunosuppressive therapy remains a major cause of liver-related morbidity and mortality in hepatitis B endemic Asia-Pacific region. This clinical practice guidel...

    George Lau, Ming-Lung Yu, Grace Wong, Alexander Thompson in Hepatology International (2021)

  6. Article

    Open Access

    Changes in acoustic cardiographic parameters before and after hemodialysis are associated with overall and cardiovascular mortality in hemodialysis patients

    Acoustic cardiography can provide simultaneous electrocardiography and acoustic cardiac data to assess the electronic and mechanical heart functions. The aim of this study was to assess whether changes in acou...

    Tung-Ling Chung, Yi-Hsueh Liu, Jiun-Chi Huang, Pei-Yu Wu in Scientific Reports (2021)

  7. Article

    Open Access

    Comparison of the effects of sibling and parental history of type 2 diabetes on metabolic syndrome

    The aim of this study was to investigate the associations between sibling history, parental history and simultaneous sibling and parental history of diabetes, and the presence of the metabolic syndrome (MetS) ...

    Hsuan Chiu, Mei-Yueh Lee, Pei-Yu Wu, Jiun-Chi Huang, Szu-Chia Chen in Scientific Reports (2020)

  8. Article

    Open Access

    There is a U shaped association between non high density lipoprotein cholesterol with overall and cardiovascular mortality in chronic kidney disease stage 3–5

    Dyslipidemia is common in patients with chronic kidney disease (CKD), however the relationship between dyslipidemia and mortality in patients with moderate to severe CKD remains controversial. Non-high-density...

    Hsuan Chiu, Pei-Yu Wu, Jiun-Chi Huang, Hung-Pin Tu, Ming-Yen Lin in Scientific Reports (2020)

  9. Article

    Open Access

    Increased Aortic Arch Calcification and Cardiomegaly is Associated with Rapid Renal Progression and Increased Cardiovascular Mortality in Chronic Kidney Disease

    Vascular calcification and cardiomegaly are highly prevalent in chronic kidney disease (CKD) patients. However, the association of the combination of aortic arch calcification (AoAC) and cardio-thoracic ratio ...

    Szu-Chia Chen, Melvin Teh, Jiun-Chi Huang, Pei-Yu Wu, Chiu-Yueh Chen in Scientific Reports (2019)

  10. Article

    Open Access

    Abnormally Low or High Ankle-Brachial Index Is Associated With the Development of Diabetic Retinopathy in Type 2 Diabetes Mellitus

    Although some studies have reported an association between peripheral artery disease (PAD) and diabetic retinopathy (DR) in patients with diabetes, whether or not a causal relationship exists is unknown. The a...

    Mei-Yueh Lee, Pi-Jung Hsiao, Jiun-Chi Huang, Wei-Hao Hsu in Scientific Reports (2018)

  11. Article

    Open Access

    Prognostic Significance of Left Ventricular Mass Index and Renal Function Decline Rate in Chronic Kidney Disease G3 and G4

    The effect of left ventricular mass index (LVMI) and estimated glomerular filtration rate (eGFR) decline rate on outcome prediction in patients with chronic kidney disease (CKD) remains unclear. We included 30...

    Jiun-Chi Huang, Szu-Chia Chen, Yi-Chun Tsai, I-Ching Kuo, Yi-Wen Chiu in Scientific Reports (2017)

  12. Article

    Open Access

    Association of Ankle-Brachial Index and Aortic Arch Calcification with Overall and Cardiovascular Mortality in Hemodialysis

    Peripheral artery occlusive disease and vascular calcification are highly prevalent in hemodialysis (HD) patients, however the association of the combination of ankle-brachial index (ABI) and aortic arch calci...

    Szu-Chia Chen, Mei-Yueh Lee, Jiun-Chi Huang, Ming-Chen Paul Shih in Scientific Reports (2016)

  13. Article

    Open Access

    Heart Rate Variability Change Before and After Hemodialysis is Associated with Overall and Cardiovascular Mortality in Hemodialysis

    Low heart rate variability (HRV) has been recognized to correlate with adverse cardiovascular (CV) outcomes in hemodialysis (HD) patients. It has been reported that HRV might be improved after HD, but whether ...

    Szu-Chia Chen, Jiun-Chi Huang, Yi-Chun Tsai, R. N. Hsiu-Chin Mai in Scientific Reports (2016)

  14. No Access

    Article

    Hepatitis C viremia interferes with serum hepatitis B virus surface antigen and DNA levels in hepatitis B uremics

    Hepatitis B virus (HBV) and HCV might cause reciprocal interference. We aimed to elucidate the influence of HCV and interleukin-28B (IL-28B) genetic variants in the HBV DNA and HBsAg levels in uremic HBV carri...

    Chung-Feng Huang, Ming-Lun Yeh, Jia-Jung Lee, Mei-Chin Chen in Hepatology International (2014)

  15. Article

    Open Access

    Atypical X-linked agammaglobulinaemia caused by a novel BTK mutation in a selective immunoglobulin M deficiency patient

    X-linked agammaglobulinaemia (XLA) is the most common inherited humoural immunodeficiency disorder. Mutations in the gene coding for Bruton’s tyrosine kinase (BTK) have been identified as the cause of XLA. Mos...

    Lee-Moay Lim, Jer-Ming Chang, I-Fang Wang, Wei-Chiao Chang in BMC Pediatrics (2013)

  16. Article

    Brachial-ankle pulse wave velocity and brachial pre-ejection period to ejection time ratio with renal outcomes in chronic kidney disease

    Heart failure and increased arterial stiffness are associated with declining renal function. This longitudinal study was designed to assess whether the combination of brachial-ankle pulse wave velocity (baPWV)...

    Szu-Chia Chen, Jer-Ming Chang, Yi-Chun Tsai, Ho-Ming Su in Hypertension Research (2012)

  17. Article

    Open Access

    Peritoneal adhesion: it can be life-threatening, and life-saving

    The inevitable post-inflammatory fibrosis and adhesion often compromises future treatment in peritoneal dialysis patients. Here, we describe a patient who experienced an unusual form of peritoneal adhesion tha...

    Jiun-Chi Huang, Szu-Chia Chen, Tsung-Kun Yang, Fang-Jung Yu, Fu Ou-Yang in BMC Nephrology (2012)

  18. Article

    The ratio of observed to predicted left ventricular mass is independently associated with increased cardiovascular events in patients with chronic kidney disease

    A condition involving the growth of the myocardium that exceeds hemodynamic needs has been reported and called as inappropriate left ventricular mass (LVM). The appropriateness of LVM can be estimated by the r...

    Szu-Chia Chen, Jer-Ming Chang, Wan-Chun Liu, Yi-Yu Chen in Hypertension Research (2012)

  19. No Access

    Article

    Chronic kidney disease prevention—a challenge for Asian countries: report of the Third Asian Forum of Chronic Kidney Disease Initiatives

    As an independent meeting, the third Asian Forum of Chronic Kidney Disease Initiatives was held on April 18–19, 2009, in Kaohsiung, Taiwan. Nearly 700 participants from 17 countries attended and 78 posters wer...

    Jer-Ming Chang, Shang-Jyh Hwang, Yusuke Tsukamoto in Clinical and Experimental Nephrology (2012)

  20. Article

    Impaired left ventricular systolic function and increased brachial-ankle pulse-wave velocity are independently associated with rapid renal function progression

    Heart failure and increased arterial stiffness are associated with declining renal function. Few studies have evaluated the association between left ventricular ejection fraction (LVEF) and brachial-ankle puls...

    Szu-Chia Chen, Tsung-Hsien Lin, Po-Chao Hsu, Jer-Ming Chang in Hypertension Research (2011)

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