41 Result(s)

Article

Mitosis and microtubule organizational changes in rice root-tip cells

The pattern of change of the microtubule cytoskeleton of the root-tip cells of rice during mitosis was studied using immunofluorescence technic and confocal laser scanning microscopy. All the major stages of c...

Shixiong Xu, Chungui Li, Cheng Zhu in Cell Research (1993)

Article

An EM algorithm for map** segregation distortion loci

Chromosomal region that causes distorted segregation ratios is referred to as segregation distortion locus (SDL). The distortion is caused either by differential representation of SDL genotypes in gametes befo...

Chengsong Zhu, Yuan-Ming Zhang in BMC Genetics (2007)

Article

Expressed sequence tags from larval gut of the European corn borer (Ostrinia nubilalis): Exploring candidate genes potentially involved in Bacillus thuringiensis toxicity and resistance

Lepidoptera represents more than 160,000 insect species which include some of the most devastating pests of crops, forests, and stored products. However, the genomic information on lepidopteran insects is very...

Chitvan Khajuria, Yu Cheng Zhu, Ming-Shun Chen, Lawrent L Buschman… in BMC Genomics (2009)

Article

Carbon and nitrogen stable isotope analyses of mammal bone fossils from the Zhongba site in the Three Gorges Reservoir region of the Yangtze River, China

Based on AMS ¹⁴C dating data, carbon and nitrogen isotope analyses were conducted on mammal bone collagen of deer, cattle and pigs from the Zhongba site in the Three Gorges Reservoir region of the Yangtze River. ...

**aoSi Tian, Cheng Zhu, ZhiBin Sun, Tao Shui, Yun** Huang… in Chinese Science Bulletin (2011)

Article

New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus

Cheng-Zhu Wu, An Na Moon, Jae-Hyuk Jang, Dongho Lee… in The Journal of Antibiotics (2011)

Article

Single nucleotide polymorphisms in the human corticosteroid-binding globulin promoter alter transcriptional activity

Corticosteroid-binding globulin (CBG) is a high-affinity plasma protein that transports glucocorticoids and progesterone. Others and we have reported non-synonymous single nucleotide polymorphisms (SNPs) that ...

Yue Li, Liang Wu, **gHui Lei, Cheng Zhu, HongMei Wang… in Science China Life Sciences (2012)

Article

Erratum to: Single nucleotide polymorphisms in the human corticosteroid-binding globulin promoter alter transcriptional activity

Yue Li, Liang Wu, **gHui Lei, Cheng Zhu, HongMei Wang… in Science China Life Sciences (2012)

Article

Diets, eco-environments and seasonal variations recorded in the oxygen and carbon isotopic compositions of mammal tooth enamel from the Shunshanji site, Sihong County, Jiangsu Province, China

The carbon and oxygen isotopic compositions of the tooth enamel of mammals, including deer, wild pigs, buffaloes and domesticated pigs from the Shunshanji site, Sihong County, Jiangsu Province, China, were ana...

**aoSi Tian, Cheng Zhu, Tao Shui, Yun** Huang in Chinese Science Bulletin (2013)

Article

MetaTopics: an integration tool to analyze microbial community profile by topic model

Deciphering taxonomical structures based on high dimensional sequencing data is still challenging in metagenomics study. Moreover, the common workflow processed in this field fails to identify microbial commun...

Jifang Yan, Guohui Chuai, Tao Qi, Fangyang Shao, Chi Zhou, Chenyu Zhu… in BMC Genomics (2017)

Article

Epigallocatechin-3-gallate enhances ER stress-induced cancer cell apoptosis by directly targeting PARP16 activity

Poly(ADP-ribose) polymerases (PARPs) are ADP-ribosylating enzymes and play important roles in a variety of cellular processes. Most small-molecule PARP inhibitors developed to date have been against PARP1, a p...

Juanjuan Wang, Chenggang Zhu, Dan Song, Ruiqi **a, Wenbo Yu… in Cell Death Discovery (2017)

Article

miR-181a-5p suppresses invasion and migration of HTR-8/SVneo cells by directly targeting IGF2BP2

Pre-eclampsia is a pregnancy-related disease that may cause maternal, neonatal and fetal morbidity and mortality and exists in 3–5% of pregnancies worldwide. The discovery of dysregulated microRNAs and their r...

Liang Wu, Wen-yan Song, Ya **e, Lin-li Hu, **ao-man Hou, Rui Wang… in Cell Death & Disease (2018)

Article

Endogenous authentic OCT4A proteins directly regulate FOS/AP-1 transcription in somatic cancer cells

OCT4A is well established as a master transcription factor for pluripotent stem cell (PSC) self-renewal and a pioneer factor for initiating somatic cell reprogramming, yet its presence and functionality in som...

Yanwen Zhou, **nyu Chen, Bo Kang, Shiqi She, **aobing Zhang… in Cell Death & Disease (2018)

Article

Subcellular stoichiogenomics reveal cell evolution and electrostatic interaction mechanisms in cytoskeleton

Eukaryotic cells contain a huge variety of internally specialized subcellular compartments. Stoichiogenomics aims to reveal patterns of elements usage in biological macromolecules. However, the stoichiogenomic...

Yu-Juan Zhang, Chengxu Zhu, Yiran Ding, Zheng-Wen Yan, Gong-Hua Li… in BMC Genomics (2018)

Article

Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta 

The placenta is crucial for a successful pregnancy and the health of both the fetus and the pregnant woman. However, how the human trophoblast lineage is regulated, including the categorization of the placenta...

Yawei Liu, **aoying Fan, Rui Wang, **aoyin Lu, Yan-Li Dang, Huiying Wang… in Cell Research (2018)

Article

De novo transcriptome and phytochemical analyses reveal differentially expressed genes and characteristic secondary metabolites in the original oolong tea (Camellia sinensis) cultivar ‘Tieguanyin’ compared with cultivar ‘Benshan’

The two original plants of the oolong tea cultivar (‘Tieguanyin’) are “Wei shuo” ‘Tieguanyin’—TGY (Wei) and “Wang shuo” ‘Tieguanyin’—TGY (Wang). Another cultivar, ‘Benshan’ (BS), is similar to TGY in its aroma...

Yuqiong Guo, Chen Zhu, Shanshan Zhao, Shuting Zhang, Wenjian Wang… in BMC Genomics (2019)

Article

Morphology and genome of a snailfish from the Mariana Trench provide insights into deep-sea adaptation

It is largely unknown how living organisms—especially vertebrates—survive and thrive in the coldness, darkness and high pressures of the hadal zone. Here, we describe the unique morphology and genome of Pseudolip...

Kun Wang, Yanjun Shen, Yongzhi Yang, **aoni Gan, Guichun Liu… in Nature Ecology & Evolution (2019)

Article

Fingerprinting cities: differentiating subway microbiome functionality

Accumulating evidence suggests that the human microbiome impacts individual and public health. City subway systems are human-dense environments, where passengers often exchange microbes. The MetaSUB project pa...

Chengsheng Zhu, Maximilian Miller, Nick Lusskin, Yannick Mahlich… in Biology Direct (2019)

Article

Genome-wide identification, molecular evolution, and expression analysis provide new insights into the APETALA2/ethylene responsive factor (AP2/ERF) superfamily in Dimocarpus longan Lour

The APETALA2/ethylene responsive factor (AP2/ERF) superfamily members are transcription factors that regulate diverse developmental processes and stress responses in plants. They have been identified in many p...

Shuting Zhang, Chen Zhu, Yumeng Lyu, Yan Chen, Zihao Zhang, Zhongxiong Lai… in BMC Genomics (2020)

Article

Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur

The antineoplastic drug carmofur is shown to inhibit the SARS-CoV-2 main protease (M^pro). Here, the X-ray crystal structure of M^pro in complex with carmofur reveals that the carbonyl reactive group of carmofur is...

Zhenming **, Yao Zhao, Yuan Sun, Bing Zhang… in Nature Structural & Molecular Biology (2020)

Article

CDE-1 suppresses the production of risiRNA by coupling polyuridylation and degradation of rRNA

Modification of RNAs, particularly at the terminals, is critical for various essential cell processes; for example, uridylation is implicated in tumorigenesis, proliferation, stem cell maintenance, and immune ...

Yun Wang, Chenchun Weng, **angyang Chen, Xufei Zhou, **nya Huang… in BMC Biology (2020)