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  1. Article

    New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus

    Cheng-Zhu Wu, An Na Moon, Jae-Hyuk Jang, Dongho Lee… in The Journal of Antibiotics (2011)

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    6-alkylsalicylic acid analogues inhibit in vitro ATPase activity of heat shock protein 90

    The molecular chaperone heat shock protein 90 (Hsp90) is responsible for maintaining the correct folding and stability of many signaling proteins. It is a promising target of cancer therapeutics and several ot...

    Cheng-Zhu Wu, An Na Moon, Oksik Choi, Sun-Young Kang… in Archives of Pharmacal Research (2010)

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    Gene-expression analysis of acidic pH shock effects on two-component systems in Streptomyces coelicolor

    In this study, transcriptional analyses by using reverse transcription-polymerase chain reaction (RT-PCR), DNA chip, and quantitative real time-PCR were performed to investigate effects of acidic pH shock on t...

    Yoon Jung Kim, An Na Moon, Jae Yang Song… in Biotechnology and Bioprocess Engineering (2009)