90 Result(s)

Article

Fully-exposed Pt-Fe cluster for efficient preferential oxidation of CO towards hydrogen purification

Hydrogen is increasingly being discussed as clean energy for the goal of net-zero carbon emissions, applied in the proton-exchange-membrane fuel cells (PEMFC). The preferential oxidation of CO (PROX) in hydrog...

Zhimin Jia, Xuetao Qin, Yunlei Chen, **angbin Cai, Zirui Gao… in Nature Communications (2022)

Article

Dusp6 deficiency attenuates neutrophil-mediated cardiac damage in the acute inflammatory phase of myocardial infarction

Dual-specificity phosphatase 6 (DUSP6) serves a specific and conserved function on the dephosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2). We previously identified Dusp6 as a regenerative ...

**aohai Zhou, Chenyang Zhang, Xueying Wu, **nli Hu, Yan Zhang… in Nature Communications (2022)

Article

Metabolite annotation from knowns to unknowns through knowledge-guided multi-layer metabolic networking

Liquid chromatography - mass spectrometry (LC-MS) based untargeted metabolomics allows to measure both known and unknown metabolites in the metabolome. However, unknown metabolite annotation is a major challen...

Zhiwei Zhou, Mingdu Luo, Haosong Zhang, Yandong Yin, Yu** Cai… in Nature Communications (2022)

Article

Direct production of olefins from syngas with ultrahigh carbon efficiency

Syngas conversion serves as a competitive strategy to produce olefins chemicals from nonpetroleum resources. However, the goal to achieve desirable olefins selectivity with limited undesired C1 by-products rem...

Hailing Yu, Caiqi Wang, Tiejun Lin, Yunlei An, Yuchen Wang… in Nature Communications (2022)

Article

Tuning crystal-phase of bimetallic single-nanoparticle for catalytic hydrogenation

Bimetallic nanoparticles afford geometric variation and electron redistribution via strong metal-metal interactions that substantially promote the activity and selectivity in catalysis. Quantitatively describi...

Shuang Liu, Yong Li, **aojuan Yu, Shaobo Han, Yan Zhou, Yuqi Yang… in Nature Communications (2022)

Article

Palladium catalyzed radical relay for the oxidative cross-coupling of quinolines

Traditional approaches for transition-metal catalyzed oxidative cross-coupling reactions rely on sp²-hybridized starting materials, such as aryl halides, and more specifically, homogeneous catalysts. We report a ...

**aorui Zhao, **aojuan Zhu, Kang Wang, Junqian Lv, Shangjun Chen… in Nature Communications (2022)

Article

Global stable-isotope tracing metabolomics reveals system-wide metabolic alternations in aging Drosophila

System-wide metabolic homeostasis is crucial for maintaining physiological functions of living organisms. Stable-isotope tracing metabolomics allows to unravel metabolic activity quantitatively by measuring th...

Ruohong Wang, Yandong Yin, **gshu Li, Hongmiao Wang, Wanting Lv… in Nature Communications (2022)

Article

Identification of ubiquitin-specific protease 32 as an oncogene in glioblastoma and the underlying mechanisms

Glioblastoma (GBM) patients present poor prognosis. Deubiquitination by deubiquitinating enzymes (DUBs) is a critical process in cancer progression. Ubiquitin-specific proteases (USPs) constitute the largest s...

Sifang Chen, ** Chen, Zhangyu Li, Jianyao Mao, Weichao Jiang, Zhi Zhu… in Scientific Reports (2022)

Article

Enhanced hydrogen generation by reverse spillover effects over bicomponent catalysts

The contribution of the reverse spillover effect to hydrogen generation reactions is still controversial. Herein, the promotion functions for reverse spillover in the ammonia borane hydrolysis reaction are pro...

Zhe Gao, Guofu Wang, Tingyu Lei, Zhengxing Lv, Mi **ong… in Nature Communications (2022)

Article

Interfacial-confined coordination to single-atom nanotherapeutics

Pursuing and develo** effective methodologies to construct highly active catalytic sites to maximize the atomic and energy efficiency by material engineering are attractive. Relative to the tremendous resear...

Limei Qin, Jie Gan, Dechao Niu, Yueqiang Cao, Xuezhi Duan… in Nature Communications (2022)

Article

Molecular determinants of response kinetics of mouse M1 intrinsically-photosensitive retinal ganglion cells

Intrinsically-photosensitive retinal ganglion cells (ipRGCs) are non-rod/non-cone retinal photoreceptors expressing the visual pigment, melanopsin, to detect ambient irradiance for various non-image-forming vi...

Yanghui Sheng, Lu**g Chen, **aozhi Ren, Zheng Jiang, King-Wai Yau in Scientific Reports (2021)

Article

Molecular-level insights into the electronic effects in platinum-catalyzed carbon monoxide oxidation

A molecular-level understanding of how the electronic structure of metal center tunes the catalytic behaviors remains a grand challenge in heterogeneous catalysis. Herein, we report an unconventional kinetics ...

Wenyao Chen, Junbo Cao, Jia Yang, Yueqiang Cao, Hao Zhang… in Nature Communications (2021)

Article

RIPK1 regulates starvation resistance by modulating aspartate catabolism

RIPK1 is a crucial regulator of cell death and survival. Ripk1 deficiency promotes mouse survival in the prenatal period while inhibits survival in the early postnatal period without a clear mechanism. Metabolism...

**nyu Mei, Yuan Guo, Zhangdan **e, Yedan Zhong, **aofen Wu… in Nature Communications (2021)

Article

Grafting nanometer metal/oxide interface towards enhanced low-temperature acetylene semi-hydrogenation

Metal/oxide interface is of fundamental significance to heterogeneous catalysis because the seemingly “inert” oxide support can modulate the morphology, atomic and electronic structures of the metal catalyst t...

Shihui Zou, Baohui Lou, Kunran Yang, Wentao Yuan, Chongzhi Zhu… in Nature Communications (2021)

Article

NEK1-mediated retromer trafficking promotes blood–brain barrier integrity by regulating glucose metabolism and RIPK1 activation

Loss-of-function mutations in NEK1 gene, which encodes a serine/threonine kinase, are involved in human developmental disorders and ALS. Here we show that NEK1 regulates retromer-mediated endosomal trafficking by...

Huibing Wang, Weiwei Qi, Chengyu Zou, Zhangdan **e, Mengmeng Zhang… in Nature Communications (2021)

Article

Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain

Aberrant sterol lipid metabolism is associated with physiological dysfunctions in the aging brain and aging-dependent disorders such as neurodegenerative diseases. There is an unmet demand to comprehensively p...

Tongzhou Li, Yandong Yin, Zhiwei Zhou, Jiaqian Qiu, Wenbin Liu… in Nature Communications (2021)

Article

Integrative analysis of key candidate genes and signaling pathways in acute coronary syndrome related to obstructive sleep apnea by bioinformatics

Although obstructive sleep apnea (OSA) has been clinically reported to be associated with acute coronary syndrome (ACS), the pathogenesis between the two is unclear. Herein, we analyzed and screened out the pr...

Yanxi Shi, Zhengye Jiang, Liqin Jiang, Jianjiang Xu in Scientific Reports (2021)

Article

Assessing the post-treatment therapeutic effect of pinaverium in irritable bowel syndrome: a randomized controlled trial

Irritable bowel syndrome (IBS) is the most common gastrointestinal disorder significantly decreasing patients’ lives of quality and placing huge economic burden on our society. Existing studies indicated that ...

Liang Zheng, Weimin Lu, Qi **ao, Yaoliang Lai, Heng Fan, Yuling Sun… in Scientific Reports (2021)

Article

Author Correction: Regulating coordination number in atomically dispersed Pt species on defect-rich graphene for n-2 butane dehydrogenation reaction

**aowen Chen, Mi Peng, **angbin Cai, Yunlei Chen, Zhimin Jia… in Nature Communications (2021)

Article

Regulating coordination number in atomically dispersed Pt species on defect-rich graphene for n-butane dehydrogenation reaction

Metal nanoparticle (NP), cluster and isolated metal atom (or single atom, SA) exhibit different catalytic performance in heterogeneous catalysis originating from their distinct nanostructures. To maximize atom...

**aowen Chen, Mi Peng, **angbin Cai, Yunlei Chen, Zhimin Jia… in Nature Communications (2021)