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Article
Antiepoetin antibody-related pure red cell aplasia: successful remission with cessation of recombinant erythropoietin alone
An elderly patient with pure red cell aplasia (PRCA) with antierythropoietin (anti-EPO) antibodies is described. PRCA due to alloimmunization is a rare and severe complication of recombinant human erythropoiet...
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Article
In Situ Monitoring of Photodynamic Inactivation of the Membrane Functions of Bacteria Using Electrochemical Sensors
The photodynamic inactivation of the membrane functions of bacteria was analyzed in situ, using K+ and tetraphenylphosphonium (TPP+) electrodes, as well as an oxygen electrode. Tetrakis(4-N-trimethylaminophenyl)p...
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Article
Pesticide discharge and water management in a paddy catchment in Japan
Concentrations of several pesticides were monitored in a paddy block and in the Kose river, which drains a paddy catchment in Fukuoka prefecture, Japan. Detailed water management in the block was also monitore...
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Article
Continuous real-time monitoring of cationic porphyrin-induced photodynamic inactivation of bacterial membrane functions using electrochemical sensors
We analysed the porphyrin-induced photodynamic inactivation of the membrane functions of bacteria through the in situ monitoring of changes in respiration rates, membrane permeability and membrane potential, usin...
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Article
Nonlinear normal modes and primary resonance of horizontally supported Jeffcott rotor
The nonlinear normal modes of a horizontally supported Jeffcott rotor are investigated. In contrast with a vertically supported rotor, there are localized and nonlocalized nonlinear normal modes because the li...
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Article
Open AccessHyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Aβ generation in Alzheimer’s disease
One of the best-characterized causative factors of Alzheimer’s disease (AD) is the generation of amyloid-β peptide (Aβ). AD subjects are at high risk of epileptic seizures accompanied by aberrant neuronal exci...
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Article
Open AccessTargeting BIG3–PHB2 interaction to overcome tamoxifen resistance in breast cancer cells
The acquisition of endocrine resistance is a common obstacle in endocrine therapy of patients with oestrogen receptor-α (ERα)-positive breast tumours. We previously demonstrated that the BIG3–PHB2 complex has ...
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Chapter
Hypotension
Hypotension is the most common side effect associated with apheresis therapy, so careful attention to monitor for this condition is needed.
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Chapter and Conference Paper
Three-Dimensional Simulation of Molecular Cloud Formation
Using three-dimensional magnetohydrodynamics simulation with the effects of radiative cooling/heating, chemical reactions, and thermal conduction, we investigate the formation of molecular cloud in the multi-p...
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Chapter
Multiple Myeloma
Plasma exchanges can be indicated when multiple myeloma or Waldenström’s macroglobulinemia is diagnosed, but it is much more important to start the treatment of ...
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Chapter
Inflammatory Bowel Diseases
Apheresis to remove leukocytes from peripheral blood is a treatment option for inflammatory bowel diseases.
A...
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Article
Open AccessCross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements
Synergistic transcriptional activation by different stimuli has been reported along with a diverse array of mechanisms, but the full scope of these mechanisms has yet to be elucidated.
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Article
Meso-scale Order Structure Prepared From Immiscible Polymer Blend Solutions
The meso-scale hexagonally packed order structures were obtained by solvent casting from the immiscible polymer blend solutions. The order structures were the result of phase separation occurred at the evapora...
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Article
Grease matrix as a versatile carrier of proteins for serial crystallography
Serial femtosecond crystallography experiments with diverse protein microcrystal suspensions are facilitated using a grease matrix as a carrier medium for sample injection.
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Chapter and Conference Paper
Stability Analysis Based on Energy Balance of Motion of the Gyroscopic Exercise Tool
This paper deals with the motion of a gyroscopic exercise tool called as the ‘Power Ball’. This gyroscopic exercise tool, which is used to train the hand muscles utilizes a gyroscopic effect caused by a whirli...
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Article
Open AccessEffects of Chronic Low-Dose Radiation on Human Neural Progenitor Cells
The effects of chronic low-dose radiation on human health have not been well established. Recent studies have revealed that neural progenitor cells are present not only in the fetal brain but also in the adult...
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Article
Synaptic Multivesicular Release in the Cerebellar Cortex: Its Mechanism and Role in Neural Encoding and Processing
The number of synaptic vesicles released during fast release plays a major role in determining the strength of postsynaptic response. However, it remains unresolved how the number of vesicles released in respo...
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Article
Promotion of protein crystal growth by actively switching crystal growth mode via femtosecond laser ablation
The protein crystal growth mechanism can be changed from planar 2D nucleation growth to spiral growth by femtosecond laser ablation. By using this method, the growth rate of a hen egg-white lysozyme crystal in...
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Article
Open AccessA RuBisCO-mediated carbon metabolic pathway in methanogenic archaea
Two enzymes are considered to be unique to the photosynthetic Calvin–Benson cycle: ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO), responsible for CO2 fixation, and phosphoribulokinase (PRK). Some arch...
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Article
C1 neurons mediate a stress-induced anti-inflammatory reflex in mice
Acute stress elicits physiological and behavioral responses that enhance survival. This study in mice shows that stress reduces tissue injury in a model of renal ischemia-reperfusion injury by activating an an...
