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Article
Open AccessUrine oxygenation predicts COVID-19 risk
Since February, 2023, the omicron variant has accounted for essentially all new coronavirus infections in Japan. If future infections involve mutant strains with the same level of infectivity and virulence as ...
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Article
Open AccessBlood perfusion with polymyxin B immobilized columns in patients with COVID-19 requiring oxygen therapy
Extracorporeal blood purification with polymyxin B immobilized fiber column direct hemoperfusion (PMX-DHP), is reported to be effective in treating COVID-19 pneumonitis with oxygen demand. This multicenter pro...
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Article
Urinary liver-type fatty acid–binding protein level as a prognostic indicator of acute kidney injury secondary to severe falciparum malaria
Acute kidney injury (AKI) secondary to severe falciparum malaria possesses a high mortality rate; however, a prognostic marker of renal dysfunction has not yet been identified. Thus, we reported a case of a pa...
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Article
Pancreaticoduodenectomy after bilirubin adsorption for distal cholangiocarcinoma with severe obstructive jaundice refractory to repeat preoperative endoscopic biliary drainage: a case report
The necessity of biliary drainage before pancreaticoduodenectomy remains controversial in cases involving malignant obstructive jaundice; however, the benefits of biliary drainage have been reported in cases w...
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Article
A case of rapidly progressive glomerulonephritis with double-positive anti-GBM antibody and MPO-ANCA after SARS-CoV-2 vaccination and relapse during 1 year follow-up
Although mRNA vaccines for COVID-19 are highly beneficial and are recommended for patients with kidney disease, adverse reactions in some patients after vaccination have been problematic. Various vasculitis an...
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Article
A case of COVID-19 reinfection in a hemodialysis patient: the role of antibody in SARS-CoV-2 infection
Hemodialysis patients are vulnerable to severe and lethal COVID-19, and their protective immunity against COVID-19 is not yet fully understood. Therefore, we report a case of COVID-19 reinfection in a hemodial...
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Article
Open AccessA case of severe generalized pustular psoriasis successfully treated with IL-17A monoclonal antibody and granulocyte removal therapy
Generalized pustular psoriasis (GPP) usually presents with fever, generalized flushing, and multiple sterile pustules on the skin, which histopathologically form subcorneal pustules characterized by Kogoj spon...
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Article
Safety of casirivimab/imdevimab administration in a SARS-CoV-2 positive maintenance dialysis patient in Japan
Controlling excessive cytokine secretion is a crucial therapeutic strategy for managing coronavirus disease 2019 (COVID-19). Patients on dialysis are at a high risk of severe disease, given abnormal immune res...
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Article
Open AccessClinical and experimental approaches for imaging of acute kidney injury
Complex molecular cell dynamics in acute kidney injury and its heterogeneous etiologies in patient populations in clinical settings have revealed the potential advantages and disadvantages of emerging novel da...
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Article
Delirium is independently associated with early mortality in elderly patients starting hemodialysis
Delirium is an independent predictor of death in patients undergoing dialysis for end-stage renal disease (ESRD). However, it is unknown whether delirium during hospitalization at the start of hemodialysis (HD...
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Article
Anion gap predicts early mortality after starting hemodialysis in the elderly
Serum anion gap (AG) has recently been proven to represent a biomarker for predicting prognosis in patients with end-stage renal disease (ESRD). However, whether change in AG (ΔAG) at the time of starting hemo...
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Chapter
Acute Kidney Injury: Transition to Chronic Kidney Disease
Acute kidney injury (AKI) is a syndrome characterized by rapid or sudden decrease in kidney function, often accompanied with oliguria, which happens within a few days. Restoration from AKI is not always simple...
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Article
Gemcitabine-induced thrombotic microangiopathy with nephrotic syndrome
We encountered a case of gemcitabine (GEM)-induced secondary thrombotic microangiopathy (TMA) with nephrotic syndrome. Advanced pancreatic cancer with liver metastasis had originally been diagnosed. Renal biop...
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Article
Open AccessThe add-on effect of the Mutsu-Senshi® skin cooling device for needle insertion pain in hemodialysis patients: a multicenter prospective study
Needle insertion pain associated with maintenance hemodialysis (HD) causes considerable stress on HD patients with native arteriovenous fistula. Skin cooling has been suggested to modify pain sensitivity and r...
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Chapter
Cryofiltration
Cryofiltration is a modification of double filtration plasmapheresis (DFPP) that involves cooling the separated plasma.
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Chapter
Plasma Exchange
Plasma exchange (PE) involves the withdrawal of blood from the circulation, centrifugal separation of the blood into plasma and cells, and return of the cellular...
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Article
Open AccessPlasma neutrophil gelatinase-associated lipocalin in acute kidney injury superimposed on chronic kidney disease after cardiac surgery: a multicenter prospective study
Plasma neutrophil gelatinase-associated lipocalin (NGAL) is reportedly useful for post-cardiac surgery acute kidney injury (AKI). Although chronic kidney disease (CKD) is a strong risk factor for AKI developme...
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Article
Antiepoetin antibody-related pure red cell aplasia: successful remission with cessation of recombinant erythropoietin alone
An elderly patient with pure red cell aplasia (PRCA) with antierythropoietin (anti-EPO) antibodies is described. PRCA due to alloimmunization is a rare and severe complication of recombinant human erythropoiet...
