75 Result(s)

Article

Salmonella effector SopB reorganizes cytoskeletal vimentin to maintain replication vacuoles for efficient infection

A variety of intracellular bacteria modulate the host cytoskeleton to establish subcellular niches for replication. However, the role of intermediate filaments, which are crucial for mechanical strength and re...

Shuangshuang Zhao, Qiu** Xu, Yanqin Cui, Su Yao, Sihui **… in Nature Communications (2023)

Article

Pollen tube emergence is mediated by ovary-expressed ALCATRAZ in cucumber

Pollen tube guidance within female tissues of flowering plants can be divided into preovular guidance, ovular guidance and a connecting stage called pollen tube emergence. As yet, no female factor has been ide...

Zhihua Cheng, **aofeng Liu, Shuangshuang Yan, Bin Liu… in Nature Communications (2023)

Article

Identification of RT-qPCR reference genes suitable for gene function studies in the pitaya canker disease pathogen Neoscytalidium dimidiatum

Neoscytalidium dimidiatum is the main causal agent of pitaya canker. Most studies of virulence and pathogenicity genes have measured expression levels using real-time quantitative polymerase chain reaction (RT-qP...

Meng Wang, Zhouwen Wang, Shuangshuang Wei, Jun **e, Jiaquan Huang… in Scientific Reports (2022)

Article

Addendum: Genome evolution and diversity of wild and cultivated potatoes

Dié Tang, Yuxin Jia, **zhe Zhang, Hongbo Li, Lin Cheng, Pei Wang, Zhigui Bao… in Nature (2022)

Article

Freeze-derived heterogeneous structural color films

Structural colors have a demonstrated value in constructing various functional materials. Efforts in this area are devoted to develo** stratagem for generating heterogeneous structurally colored materials wi...

Shuangshuang Miao, Yu Wang, Lingyu Sun, Yuan** Zhao in Nature Communications (2022)

Article

Analysis of immune related gene expression profiles and immune cell components in patients with Barrett esophagus

Barrett's esophagus (BE) is a well-known precancerous condition of esophageal adenocarcinoma. However, the immune cells and immune related genes involved in BE development and progression are not fully underst...

Lin Shi, Renwei Guo, Zhuo Chen, Ruonan Jiao, Shuangshuang Zhang… in Scientific Reports (2022)

Article

Genome evolution and diversity of wild and cultivated potatoes

Potato (Solanum tuberosum L.) is the world’s most important non-cereal food crop, and the vast majority of commercially grown cultivars are highly heterozygous tetraploids. Advances in diploid hybrid breeding bas...

Dié Tang, Yuxin Jia, **zhe Zhang, Hongbo Li, Lin Cheng, Pei Wang, Zhigui Bao… in Nature (2022)

Article

Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists

Small-molecule modulators of TLR8 have drawn much interests as it plays pivotal roles in the innate immune response to single-stranded RNAs (ssRNAs) derived from viruses. However, their clinical uses are limit...

Yi Yang, Adam Csakai, Shuangshuang Jiang, Christina Smith… in Nature Communications (2021)

Article

Room-temperature oxygen vacancy migration induced reversible phase transformation during the anelastic deformation in CuO

From the mechanical perspectives, the influence of point defects is generally considered at high temperature, especially when the creep deformation dominates. Here, we show the stress-induced reversible oxygen...

Lei Li, Guoxujia Chen, He Zheng, Weiwei Meng, Shuangfeng Jia… in Nature Communications (2021)

Article

Neutrophil to lymphocyte ratio and fibrinogen values in predicting patients with type B aortic dissection

The aim of this study is to detect the diagnosis value of neutrophil lymphocyte ratio (NLR) and fibrinogen (FIB) in type B aortic dissection (TBAD) patients. This retrospective observation study consisted pati...

Shuangshuang Li, ** Yang, Jian Dong, Renle Guo, Sheng Chang… in Scientific Reports (2021)

Article

Salmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence

Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, ...

Lingyan Jiang, Peisheng Wang, **aorui Song, Huan Zhang… in Nature Communications (2021)

Article

An economic and disease transmission model of human papillomavirus and oropharyngeal cancer in Texas

In 2017, 46,157 and 3,127 new oropharyngeal cancer (OPC) cases were reported in the U.S. and Texas, respectively. About 70% of OPC were attributed to human papillomavirus (HPV). However, only 51% of U.S. and 4...

Chengxue Zhong, Li Xu, Ho-Lan Peng, Samantha Tam, Li Xu… in Scientific Reports (2021)

Article

Role of prenatal imaging in the diagnosis and management of fetal facio-cervical masses

Congenital facio-cervical masses can be a developmental anomaly of cystic, solid, or vascular origin, and have an inseparable relationship with adverse prognosis. This retrospective cross-sectional study aimed...

Weizeng Zheng, Shuangshuang Gai, Jiale Qin, Fei Qiu, Baohua Li… in Scientific Reports (2021)

Article

Bioinformatic map** of a more precise Aspergillus niger degradome

Aspergillus niger has the ability to produce a large variety of proteases, which are of particular importance for protein digestion, intracellular protein turnover, cell signaling, flavour development, extracellu...

Zixing Dong, Shuangshuang Yang, Byong H. Lee in Scientific Reports (2021)

Article

H2AK121ub in Arabidopsis associates with a less accessible chromatin state at transcriptional regulation hotspots

Although it is well established that the Polycomb Group (PcG) complexes maintain gene repression through the incorporation of H2AK121ub and H3K27me3, little is known about the effect of these modifications on ...

**aochang Yin, Francisco J. Romero-Campero, Pedro de Los Reyes… in Nature Communications (2021)

Article

Cloning of wheat keto-acyl thiolase 2B reveals a role of jasmonic acid in grain weight determination

Grain weight (GW) is one of the component traits of wheat yield. Existing reports have shown that multiple phytohormones are involved in the regulation of GW in different crops. However, the potential role of ...

Yun Chen, Yan Yan, Tian-Tian Wu, Guo-Liang Zhang, Huanran Yin… in Nature Communications (2020)

Article

Ultralong lifetime and efficient room temperature phosphorescent carbon dots through multi-confinement structure design

Room temperature phosphorescence materials have inspired extensive attention owing to their great potential in optical applications. However, it is hard to achieve a room temperature phosphorescence material w...

Yuqiong Sun, Shuting Liu, Luyi Sun, Shuangshuang Wu, Guangqi Hu… in Nature Communications (2020)

Article

The prostaglandin synthases, COX-2 and L-PGDS, mediate prostate hyperplasia induced by low-dose bisphenol A

This study aimed to identify prostaglandin synthases (PGS) that mediate bisphenol A (BPA)-induced prostatic hyperplasia and explore their underlying mechanisms. In an in vivo study, male adult Sprague–Dawley r...

Shuangshuang Wu, Dongyan Huang, **n Su, Han Yan, Aicui Ma, Lei Li… in Scientific Reports (2020)

Article

REV7 is required for processing AID initiated DNA lesions in activated B cells

Activation-induced cytidine deaminase (AID) initiates both antibody class switch recombination (CSR) and somatic hypermutation (SHM) in antibody diversification. DNA double-strand break response (DSBR) factors...

Dingpeng Yang, Ying Sun, **g**g Chen, Ying Zhang… in Nature Communications (2020)

Article

Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis

Due to their bacterial ancestry, many components of mitochondria share structural similarities with bacteria. Release of molecular danger signals from injured cell mitochondria (mitochondria-derived damage-ass...

** An, Lin-Lin Wei, Shuangshuang Zhao, Deanna Y. Sverdlov… in Nature Communications (2020)