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  1. Article

    Open Access

    Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis

    Due to their bacterial ancestry, many components of mitochondria share structural similarities with bacteria. Release of molecular danger signals from injured cell mitochondria (mitochondria-derived damage-ass...

    ** An, Lin-Lin Wei, Shuangshuang Zhao, Deanna Y. Sverdlov in Nature Communications (2020)

  2. No Access

    Article

    Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease

    Kwong et al. use nanoparticles coated with protease substrates to generate mass-encoded synthetic biomarkers for sensitive detection of fibrosis and cancer in mice.

    Gabriel A Kwong, Geoffrey von Maltzahn, Gayathree Murugappan in Nature Biotechnology (2013)