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Article
Topical corticosteroids for the prevention of severe radiation dermatitis: a systematic review and meta-analysis
Radiation dermatitis (RD) is a frequently occurring adverse reaction during radiotherapy in cancer patients. While the use of topical corticosteroids (TCs) is common for the treatment of RD, its role in preven...
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Article
Open AccessCetuximab and anemia prevention in head and neck cancer patients undergoing radiotherapy
Epidermal growth factor receptor (EGFR) activation is associated with increased production of interleukin 6 (IL6), which is intensified by radiotherapy (RT) induced inflammatory response. Elevated IL6 levels i...
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Article
Open AccessAn economic and disease transmission model of human papillomavirus and oropharyngeal cancer in Texas
In 2017, 46,157 and 3,127 new oropharyngeal cancer (OPC) cases were reported in the U.S. and Texas, respectively. About 70% of OPC were attributed to human papillomavirus (HPV). However, only 51% of U.S. and 4...
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Article
Open AccessThe epigenetic regulators and metabolic changes in ferroptosis-associated cancer progression
Ferroptosis, a novel form of regulated cell death, is different from other types of cell death in morphology, genetics and biochemistry. Increasing evidence indicates that ferroptosis has significant implicati...
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Article
Loss of p53 drives neuron reprogramming in head and neck cancer
The solid tumour microenvironment includes nerve fibres that arise from the peripheral nervous system1,2. Recent work indicates that newly formed adrenergic nerve fibres promote tumour growth, but the origin of t...
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Article
Cutaneous Squamous Cell Carcinoma in Immunosuppressed Patients
Cutaneous squamous cell carcinoma is the second most common dermatologic malignancy worldwide. A major risk factor for development of new lesions and more aggressive disease is immunosuppression. This study is...
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Article
Open AccessAge-Structured Population Modeling of HPV-related Cervical Cancer in Texas and US
Human papillomavirus (HPV)–related cervical cancer is a major public health threat to women, with >10,000 new cases diagnosed annually in the United States between 2008 and 2012. Since HPV vaccines can protect...
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Article
Open AccessMutation status among patients with sinonasal mucosal melanoma and its impact on survival
Sinonasal mucosal melanoma (SNMM) comprises <1% of all melanomas and lacks well-characterised molecular markers. Our aim was to determine the frequencies of common mutations and examine their utility as molecu...
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Article
Open AccessMedialization thyroplasty versus injection laryngoplasty: a cost minimization analysis
Medialization thyroplasty and injection laryngoplasty are widely accepted treatment options for unilateral vocal fold paralysis. Although both procedures result in similar clinical outcomes, little is known ab...