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Article
Based on ARASENS trial: efficacy and safety of darolutamide as an emerging option of endocrinotherapy for metastatic hormone-sensitive prostate cancer—an updated systematic review and network meta-analysis
The newly published ARASENS trial has demonstrated the clinical efficacy of darolutamide for metastatic hormone-sensitive prostate cancer (mHSPC). However, the use of darolutamide as the latest first-line andr...
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Article
Low-carbon cities comprehensive evaluation method based on Fermatean fuzzy hybrid distance measure and TOPSIS
Low-carbon city (LCC) quality evaluation is getting increasingly attention in recent years. However, uncertainty decision-making processes and complicated indicators in LCC development have brought challenges ...
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Article
Open AccessClinical features of uterine sarcomas presenting mainly with uterine masses: a retrospective study
Uterine sarcomas are uncommon mesenchymal tumors of the uterus. The clinical problem is that the features of uterine sarcomas can sometimes mimic uterine fibroids. This study aims to investigate the clinical c...
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Article
Prevalence of mismatch repair genes mutations and clinical activity of PD-1 therapy in Chinese prostate cancer patients
Prostate cancer (PCa) patients with mismatch repair (MMR) genes mutations are potentially responsive to immune checkpoint blockade (ICB). However, aberrations in MMR genes were rare in PCa and there is evidenc...
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Article
A Combined Weighting Based Large Scale Group Decision Making Framework for MOOC Group Recommendation
Massive open online courses (MOOC) are free learning courses based on online platforms for higher education, which not only promote the open sharing of learning resources, but also lead to serious information ...
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Article
Financial information, green certification, government subsidies and green bond credit spreads–evidence from China
In the context of green bonds playing an increasingly vital role in the green financial market, this study selects 61 green bonds issued in China from 2016 to 2021 as samples to examine the factors influencing...
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Article
Open AccessNomograms for predicting survival in patients with micropapillary bladder cancer: a real-world analysis based on the surveillance, epidemiology, and end results database and external validation in a tertiary center
The present study aimed to construct and validate nomograms that can be used to predict cancer-specific survival (CSS) and overall survival (OS) in patients with micropapillary bladder cancer.
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Article
The function of Prostate Health Index in detecting clinically significant prostate cancer in the PI-RADS 3 population: a multicenter prospective study
The purpose of this study is to identify patients in the prostate imaging reporting and data system (PI-RADS) 3 population who need biopsy by using prostate health index (PHI) and other clinical parameters in ...
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Article
Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis
Metastasis is the leading cause of cancer-related deaths and myeloid cells are critical in the metastatic microenvironment. Here, we explore the implications of reprogramming pre-metastatic niche myeloid cells...
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Article
Robot-assisted radical prostatectomy using a novel urethral reconstruction technique vs standard vesicourethral anastomosis. A retrospective cohort study
Urinary incontinence is a common postoperative complication of radical prostatectomy (RP). In order to improve postoperative urinary continence rate, we proposed a urethral reconstruction technique which can p...
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Article
A probabilistic linguistic and dual trust network-based user collaborative filtering model
Recommendation models for network information that are generally based on user ratings fail to utilize user online behaviours such as reviews and likes, which indicate users’ opinions, attitudes, and emotions....
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Article
Evaluation of prostate health index in predicting bone metastasis of prostate cancer before bone scanning
In patients undergoing bone scanning, the positive rate of bone metastasis (BM) of prostate cancer (PCa) is quite low. The main purpose of this study was to explore the application of %p2PSA and prostate healt...
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Article
Multidimensional Measurement and Comparison of China’s Educational Inequality
Educational equity significantly supports the creation of a harmonious society, which has become one of the Sustainable Development Goals of the United Nations for 2030. China’s education level has greatly imp...
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Article
Open AccessArterioureteral fistula after radical cystectomy and ureterocutaneostomy: two case reports and a systematic literature review
Arterioureteral fistula (AUF) is a rare, life-threatening condition wherein communication occurs between a ureter and the common, internal, or external iliac artery. The sensitivity of common clinical imaging ...
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Article
A Fuzzy-Social Network Multi-criteria Group Decision-Making Framework for Selection of Renewable Energy Project: A Case of China
The proper selection of a renewable energy project (REP) is the key to give play to regional resource advantages and optimize the energy consumption structure. As a complex multi-criteria group decision-making...
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Article
Open AccessComprehensive analysis of N6-methyladenosine regulators with the tumor immune landscape and correlation between the insulin-like growth factor 2 mRNA-binding protein 3 and programmed death ligand 1 in bladder cancer
N6-methyladenosine (m6A) is one of the most abundant post-transcriptional modifications of RNA. However, there is limited information about the potential roles of m6A regulators in tumor immunity. Therefore, in t...
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Article
Open AccessAssociations of COVID-19 lockdown with gestational length and preterm birth in China
The effects of COVID-19 lockdown measures on maternal and fetal health remain unclear. We examined the associations of COVID-19 lockdown with gestational length and preterm birth (PTB) in a Chinese population.
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Article
Proposal for temperature-independent optical sensor based on asymmetric Mach–Zehnder interferometer
An optical sensor based on dual asymmetric Mach–Zehnder interferometers (AMZIs) cascade with temperature-independent is proposed. The optical sensor based on AMZI is very sensitive to the change of ambient tem...
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Article
Open AccessTP53 alterations of hormone-naïve prostate cancer in the Chinese population
Prostate cancer (PCa) shows racial disparity in clinical and genomic characteristics, and Asian patients with PCa often present with more aggressive phenotypes at diagnosis. The ability of TP53 to serve as a p...
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Article
Open AccessKDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1
KDM6A, a histone demethylase, is frequently mutated in bladder cancer (BCa). However, the role and detailed molecular mechanism of KDM6A involved in bladder cancer progression remains unknown.