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Mechanism of Coal Permeability Enhancement by a Series of Mechanically Over-excavated Cavities Along Drainage Boreholes
To solve the difficult problems of gas drainage in coal seams with a high gas content and low permeability, a novel technology based on a series of mechanically over-excavated cavities along drainage boreholes...
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Multiple attribute decision-making based on a prospect theory-based TOPSIS method for venture capital selection with complex information
Venture capitalists are heavily influenced by their psychological state and intuition when making investment decisions in uncertain investment environments. To choose promising enterprises in China, it is nece...
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A multi-criteria comprehensive evaluation framework of online learning platform based on Pythagorean probabilistic linguistic information
The popularization of online education, particularly the impact of the COVID-19 pandemic in the past few years, has promoted the development of online learning platforms. Consequently, the importance of optima...
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Low-carbon cities comprehensive evaluation method based on Fermatean fuzzy hybrid distance measure and TOPSIS
Low-carbon city (LCC) quality evaluation is getting increasingly attention in recent years. However, uncertainty decision-making processes and complicated indicators in LCC development have brought challenges ...
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Open AccessMDM2 inhibitor APG-115 exerts potent antitumor activity and synergizes with standard-of-care agents in preclinical acute myeloid leukemia models
Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous clonal disease associated with unmet medical needs. Paralleling the pathology of other cancers, AML tumorigenesis and propagation can ...
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Open AccessMDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment
Programmed death-1 (PD-1) immune checkpoint blockade has achieved clinical successes in cancer therapy. However, the response rate of anti-PD-1 agents remains low. Additionally, a subpopulation of patients dev...
