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An Hsp70 promoter–based mouse for heat shock–induced gene modulation
AbstractPhysical therapy is extensively employed in clinical settings. Nevertheless, the absence of suitable animal models has resulted in an...
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X-ray reflectivity study of the heat shock protein Hsp70 interaction with an artificial cell membrane model
Membrane-bound heat shock protein 70 (Hsp70) apart from its intracellular localization was shown to be specifically expressed on the plasma membrane...
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Assessment of Heat-Shock Protein Hsp70 Colocalization with Markers of Tumor Stem-Like Cells
AbstractThe search of biomarkers for early diagnosis and theranostics of glioblastoma multiforme (GBM) due to the aggressiveness of the disease is an...
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Heat shock protein 70 kDa (HSP70) is involved in the maintenance of pig sperm function throughout liquid storage at 17 °C
At present, liquid storage is the most efficient method for pig semen preservation. This approach relies upon reducing sperm metabolism, allowing for...
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Transfection of Heat Shock Protein 70 kDa (HSP70)
Heat shock protein 70 kDa (HSP70) is a major protein family in the cell protections against stress-induced denaturation and aggregation and in the...
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Hygrophila auriculata Improves Insulin Resistance by Reducing Oxidative Stress, Membrane Stabilization and Increasing Hepatic Heat Shock Protein 70 (Hsp70) Expression
The present study aimed to evaluate the effect of the methanolic extract of Hygrophila auriculata (Schumach.) Heine, Acanthaceae, in obesity-induced...
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Contraction of Heat Shock Protein 70 Genes Uncovers Heat Adaptability of Ostrea denselamellosa
The milin oyster Ostrea denselamellosa is a live-bearing species with a sharp decline in the natural population. Unlike other oysters, O....
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Regulation of the heat shock response by heat shock transcription factors
The heat shock response is characterized by a rapid and robust increase in heat shock proteins upon exposure to protein-damaging stresses. This...
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Linking Heat Shock Protein 70 and Parkin in Parkinson’s Disease
Parkinson’s disease (PD) is a neurodegenerative disease that affects millions of elderly people worldwide and is characterized by the progressive...
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A genome-wide screening of the 70 kDa heat shock protein (HSP70) genes in the rotifer Brachionus plicatilis sensu stricto with a characterization of two heat-inducible HSP70 genes
The 70 kDa heat shock proteins (HSP70s) and the constitutive members of the HSP70 family (heat shock cognates; HSC70s) play essential roles in...
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Heat shock protein paradigms in cancer progression: future therapeutic perspectives
Heat-shock proteins (HSPs), also known as stress proteins, are ubiquitously present in all forms of life. They play pivotal roles in protein folding...
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Contribution of HIF-1α to Heat Shock Response by Transcriptional Regulation of HSF1/HSP70 Signaling Pathway in Pacific Oyster, Crassostrea gigas
Ocean temperature rising drastically threatens the adaptation and survival of marine organisms, causing serious ecological impacts and economic...
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Effects of resistance training on heat shock response (HSR), HSP70 expression, oxidative stress, inflammation, and metabolism in middle-aged people
Resistance training (RT) can increase the heat shock response (HSR) in the elderly. As middle-aged subjects already suffer physiological declines...
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Systematic analysis of Heat Shock Protein 70 (HSP70) gene family in radish and potential roles in stress tolerance
The 70 kD heat shock proteins (HSP70s) represent a class of molecular chaperones that are widely distributed in all kingdoms of life, which play...
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Insilico-based genome-wide identification and structural characterization of heat shock proteins 70 (HSP70) in cowpea (Vigna unguiculata L.)
Heat shock protein 70 is conserved a family of ubiquitously expressed proteins that help plants to withstand the major abiotic stresses. Although HSP70 ...
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HSP70-HSP90 Chaperone Networking in Protein-Misfolding Disease
Molecular chaperones and their associated co-chaperones are essential in health and disease as they are key facilitators of protein-folding, quality...
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Heat shock protein A2 is a novel extracellular vesicle-associated protein
70-kDa Heat Shock Proteins (HSPA/HSP70) are chaperones playing a central role in the proteostasis control mechanisms. Their basal expression can be...
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Heat shock protein 70 is associated with duration of cell proliferation in early pod development of soybean
Pod is an important organ for seed production in soybean. Pod size varies among soybean cultivars, but the mechanism is largely unknown. Here we...
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Can heat shock protein 70 (HSP70) serve as biomarkers in Antarctica for future ocean acidification, warming and salinity stress?
The Antarctic Peninsula is one of the fastest-warming places on Earth. Elevated sea water temperatures cause glacier and sea ice melting. When...
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Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis
A high-fat diet increases the risk of insulin resistance, type-2 diabetes, and non-alcoholic steato-hepatitis. Here we identified two heat-shock...
