Search
Search Results
-
Identification of potentially functional circRNAs and prediction of the circRNA-miRNA-hub gene network in mice with primary blast lung injury
ObjectivesPrimary blast lung injury (PBLI) is the main cause of death in blast injury patients, and is often ignored due to the absence of a specific...
-
Identification of novel prognostic circRNA biomarkers in circRNA-miRNA-mRNA regulatory network in gastric cancer and immune infiltration analysis
BackgroundGastric cancer (GC) carries significant morbidity and mortality globally. An increasing number of studies have confirmed that circular RNA...
-
Construction and integrated analysis of the ceRNA network hsa_circ_0000672/miR-516a-5p/TRAF6 and its potential function in atrial fibrillation
Atrial fibrosis is a crucial contributor to initiation and perpetuation of atrial fibrillation (AF). This study aimed to identify a...
-
The integrative multi-omics approach identifies the novel competing endogenous RNA (ceRNA) network in colorectal cancer
Circular RNAs (circRNA) are known to function as competing endogenous RNA (ceRNA) in various cancers by regulating microRNAs (miRNA). However, in...
-
circRNA-miRNA-mRNA network analysis to explore the pathogenesis of abnormal spermatogenesis due to aberrant m6A methylation
Many studies have shown that circRNAs and miRNAs play important roles in many different life processes. However, the function of circRNAs in...
-
Develo** and validating a survival prediction model based on blood exosomal ceRNA network in patients with PAAD
BackgroundAmong the most lethal cancers, pancreatic adenocarcinoma (PAAD) is an essential component of digestive system malignancies that still lacks...
-
Systematic analysis of various RNA transcripts and construction of biological regulatory networks at the post-transcriptional level for chronic obstructive pulmonary disease
BackgroundAlthough chronic inflammation, oxidative stress, airway remodeling, and protease-antiprotease imbalance have been implicated in chronic...
-
Identification of the cuproptosis-related ceRNA network and risk model in acute ischemic stroke by integrated bioinformatics analysis
BackgroundAcute ischemic stroke (AIS) is one of the leading contributors to death and disability in adults. And cuproptosis is a novel type of cell...
-
Integrated analysis of lncRNA/circRNA–miRNA–mRNA in the proliferative phase of liver regeneration in mice with liver fibrosis
BackgroundNon-coding RNAs play important roles in liver regeneration; however, their functions and mechanisms of action in the regeneration of...
-
Integrated bioinformatics analysis for exploring potential biomarkers related to Parkinson’s disease progression
BackgroundParkinson’s disease (PD) is a progressive neurodegenerative disease with increasing prevalence. Effective diagnostic markers and...
-
Construction of a circRNA-miRNA-mRNA network based on differentially co-expressed circular RNA in gastric cancer tissue and plasma by bioinformatics analysis
BackgroundIncreasing evidence implicates circular RNAs (circRNAs) have been involved in human cancer progression. However, the mechanism remains...
-
Identifying circRNA-associated-ceRNA networks in juvenile spondyloarthropathies patients
BackgroundJuvenile spondyloarthropathies (JSpA) are defined as a heterogeneous group of diseases that start before the age of 16. The study aimed to...
-
The investigation of circRNA profiling reveals the regulatory role of the hsa_circ_0000375/miR-7706 pathway in breast cancer
BackgroundCircular RNAs (circRNAs) take an effect on tumorigenesis and progression. However, circRNAs have not been systematically identified in...
-
Identification of Key lncRNAs, circRNAs, and mRNAs in Osteoarthritis via Bioinformatics Analysis
Osteoarthritis (OA) is a common degenerative joint disorder that adversely affects the quality of life of patients. Identification of novel...
-
Multiple transcriptome analyses reveal mouse testis developmental dynamics
The testes are the organs of gamete production and testosterone synthesis. Up to date, no model system is available for mammalian testicular...
-
CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
BackgroundCalcific aortic valve disease (CAVD) is a common valve disease with an increasing incidence, but no effective drugs as of yet. With the...
-
Exploration and bioinformatic prediction for profile of mRNA bound to circular RNA BTBD7_hsa_circ_0000563 in coronary artery disease
BackgroundAs a novel circRNA, BTBD7_hsa_circ_0000563 has not been fully investigated in coronary artery disease (CAD). Our aim is to reveal the...
-
Bioinformatic Analysis of miR-200b/429 and Hub Gene Network in Cervical Cancer
The miR-200b/429 located at 1p36 is a highly conserved miRNA cluster emerging as a critical regulator of cervical cancer. Using publicly available...
-
Whole-transcriptome profiling across different developmental stages of Aedes albopictus (Diptera: Culicidae) provides insights into chitin-related non-coding RNA and competing endogenous RNA networks
BackgroundThe Asian tiger mosquito, Aedes albopictus , is one of the most invasive species and a vector of numerous arboviruses. The deleterious...
-
Construction of circRNA-miRNA-mRNA network and identification of novel potential biomarkers for non-small cell lung cancer
BackgroundThe underlying circular RNAs (circRNAs)-related competitive endogenous RNA (ceRNA) mechanisms of pathogenesis and prognosis in non-small...
