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Assessing Reflection Usage with Mutation Testing Augmented Analysis
Reflection is a powerful tool that allows a program to manipulate itself during its execution. However, developers may use it to circumvent data...
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In silico induction of missense mutation in NNRTI protein: computational modelling and stability study of modelled proteins
The paper presents in silico mutational research on the energetics of the most resolved protein structure of HIV-1 NNRTIs, the 4G1Q HIV-1 reverse...
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Mutation Work on Other Ornamental Plants
The chapter covers mutation work (mutagens, working dose, mutants) carried out throughout the world on approximately 120 ornamental crops.
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Macrophage profiling in atherosclerosis: understanding the unstable plaque
The development and rupture of atherosclerotic plaques is a major contributor to myocardial infarctions and ischemic strokes. The dynamic evolution...
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MTUL: Towards Mutation Testing of Unsupervised Learning Systems
Unsupervised learning (UL) is one of the most important areas in artificial intelligence. UL systems are capable of learning patterns from unlabeled...
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Robustness-Enhanced Assertion Generation Method Based on Code Mutation and Attack Defense
Writing high-quality unit tests plays a crucial role in discovering and diagnosing early-stage errors and preventing their further propagation...
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Identification of a novel compound heterozygous mutation and a homozygous mutation of SLURP1 in Chinese families with Mal de Meleda
BackgroundMal de Meleda is an autosomal recessive palmoplantar keratoderma, with SLURP1 identified as the pathogenic gene responsible. Although over...
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Dynamic Response Characteristics of Rolling Bearing with Clearance Under Unstable Conditions
Rolling bearing exhibits complex dynamic characteristics under unstable conditions, which can lead to the deterioration of internal contact state for...
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Identifying unstable CNG repeat loci in the human genome: a heuristic approach and implications for neurological disorders
Tandem nucleotide repeat (TNR) expansions, particularly the CNG nucleotide configuration, are associated with a variety of neurodegenerative...
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Selection-Mutation Models
In this chapter,we discuss the class of selection-mutation models. This class of models describe populations that are structured by, in addition to...
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Estimation of Microbial Mutation Rates in Tuberculosis Research
Antibiotic resistance is a dominant theme in tuberculosis research. Quantitative studies on microbial mutation rates play a key role in drug...
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New failure criterion for rock slopes with intermittent joints based on energy mutation
Step-path failure is a typical unstable mode of rock slopes with intermittent joints, and the accurate prediction of their stability is of great...
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Unstable hemoglobin Montreal II uncovered in an adult with unexplained hemolysis exacerbated by a presumed viral infection: a case report
BackgroundUnstable hemoglobinopathies are rare inherited disorders of hemoglobin causing a reduction of hemoglobin molecule solubility. This results...
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Order-of-Mutation Effects on Cancer Progression: Models for Myeloproliferative Neoplasm
In some patients with myeloproliferative neoplasms (MPN), two genetic mutations are often found: JAK2 V617F and one in the TET2 gene. Whether one...
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A Discrete-Time Predator-Prey Model with Selection and Mutation
We study a discrete-time predator-prey system with selection and mutation in the prey population where individuals are distributed over a finite...
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Mutation Breeding Research in Sweet Pepper
Sweet pepper is delicious, loved, and an increasingly popular nutritional vegetable that is grown and produced in significant amounts throughout the...
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Mechanical Failure Mechanisms of Unstable Rock Masses with Sandstone and Mudstone Interbeds as the Base
Based on the comprehensive analysis of the origin and structural characteristics, this study established the physical and mechanical models of an...
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In silico analysis of the Val66Met mutation in BDNF protein: implications for psychological stress
The brain-derived neurotrophic factor (BDNF) involves stress regulation and psychiatric disorders. The Val66Met polymorphism in the BDNF gene has...
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Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity
Acute myeloid leukemia (AML) has a poor prognosis and a heterogeneous mutation landscape. Although common mutations are well-studied, little research...
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A Cysteinyl-tRNA Synthetase Mutation Causes Novel Autosomal-Dominant Inheritance of a Parkinsonism/Spinocerebellar-Ataxia Complex
This study aimed to identify possible pathogenic genes in a 90-member family with a rare combination of multiple neurodegenerative disease...
