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Boosting nuclear-targeted photothermal-chemotherapy by NIR-responsive hybrid membrane camouflaged nanotherapeutics
BackgroundEngineering nanotherapeutics have been extensively studied for cancer therapy. However, the therapeutic efficacy is still severely...
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Nanotherapeutics for Neurological Disorders
The World Health Organization (WHO) report on “Neurological disorders: Public health challenges” (2006), a collaborative international survey...
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Tumor microenvironment-responsive metal nanotherapeutics for breast cancer chemo-/immunotherapy
Many metal complexes not only had excellent cytotoxic antitumor effects but also could function as a positive immunomodulatory to improve antitumor...
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Age-associated disparity in phagocytic clearance affects the efficacy of cancer nanotherapeutics
Nanomedicines have been approved to treat multiple human diseases. However, clinical adoption of nanoformulated agents is often hindered by concerns...
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Multi-bioinspired Sprayable Nanotherapeutics for Tumor-Specific Focal Cancer Therapy
Chemotherapy is commonly used to treat cancer. However, insufficient retention at the target site and systemic toxicity remains critical challenges....
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Cardiomyocyte-targeted anti-inflammatory nanotherapeutics against myocardial ischemia reperfusion (IR) injury
Myocardial ischemia reperfusion (IR) injury is closely related to the overwhelming inflammation in the myocardium. Herein, cardiomyocyte-targeted...
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Cancer Nanotherapeutics
Diverse nanomodules, engineered nanomaterials, and methods have paved the way for state-of-the-art cancer chemotherapies and immunotherapies...
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Novel nanotherapeutics for cancer immunotherapy by albumin nanoparticles functionalized with PD-1 and PD-L1 aptamers
BackgroundPD-1/PD-L1 blockade plays a crucial role in cancer immunotherapy. Exploration of new technologies to further enhance the efficacy of...
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Development of Efficient Strategies for Physical Stimuli-Responsive Programmable Nanotherapeutics
Stimuli-responsive nanomaterials have received lots of attention in biomedical research due to their responsiveness to different therapies under...
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Nanotherapeutics for Viral Diseases of Animals
Prevention is no doubt the best strategy to combat viral diseases as the options of antiviral therapeutics are limited. The shortage is even more...
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Application of MOF-based nanotherapeutics in light-mediated cancer diagnosis and therapy
Light-mediated nanotherapeutics have recently emerged as promising strategies to precisely control the activation of therapeutic reagents and imaging...
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Designed fabrication of active tumor targeting covalent organic framework nanotherapeutics via a simple post-synthetic strategy
Develo** agents that can accurately differentiate tumors from normal healthy tissues is of utmost importance for safe cancer therapy. Active...
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Mucoadhesive, antioxidant, and lubricant catechol-functionalized poly(phosphobetaine) as biomaterial nanotherapeutics for treating ocular dryness
Dry eye disease (DED) is associated with ocular hyperosmolarity and inflammation. The marketed topical eye drops for DED treatment often lack...
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New insights into nanotherapeutics for periodontitis: a triple concerto of antimicrobial activity, immunomodulation and periodontium regeneration
Periodontitis is a chronic inflammatory disease caused by the local microbiome and the host immune response, resulting in periodontal structure...
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Nanotherapeutics for Bacterial Livestock Diseases
Microbial diversity and abundance is so vast that almost no single corner on this earth is unoccupied by pathogenic bacteria. Animals and human...
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Remodeling the hepatic fibrotic microenvironment with emerging nanotherapeutics: a comprehensive review
Liver fibrosis could be the last hope for treating liver cancer and remodeling of the hepatic microenvironment has emerged as a strategy to promote...
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Tea leaf-derived exosome-like nanotherapeutics retard breast tumor growth by pro-apoptosis and microbiota modulation
While several artificial nanodrugs have been approved for clinical treatment of breast tumor, their long-term applications are restricted by...
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Assessment of gemcitabine hydrochloride-based nanotherapeutics in cancer: a proof of concept study
AbstractCancer remains a serious health problem in terms of incidence and mortality worldwide. As a result, researchers are working to identify new...
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Nanotherapeutics with immunoregulatory functions for the treatment of bacterial infection
The advent of drug-resistant pathogens results in the occurrence of stubborn bacterial infections that cannot be treated with traditional...
