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Showing 81-100 of 10,000 results
  1. Ex vivo cultivated retinal pigment epithelial cell transplantation for the treatment of rabbit corneal endothelial dysfunction

    Objective

    Stem cell therapy is a promising strategy for the treatment of corneal endothelial dysfunction, and the need to find functional alternative...

    Chunxiao Dong, Dulei Zou, ... Zongyi Li in Eye and Vision
    Article Open access 02 August 2023
  2. An In Vitro Bilayer Model of Human Primary Retinal Pigment Epithelial and Choroid Endothelial Cells for Permeability Studies

    The blood-retinal barrier (BRB) present in the posterior chamber of the eye plays a major role in maintaining the proper function and integrity of...
    Karthikka Palanisamy, Subbulakshmi Chidambaram in Vascular Hyperpermeability
    Protocol 2024
  3. Outcomes of retinal pigment epithelial detachment in Vogt-Koyanagi-Harada disease: a longitudinal analysis

    Background

    The aim of this study was to report the clinical profile and outcomes of retinal pigment epithelial detachment (PED) in...

    Chuanzhen Zheng, Kaixuan Wang, ... **aomin Zhang in BMC Ophthalmology
    Article Open access 19 November 2022
  4. Increased sodium fluorescein transport by corticosteroids is inhibited by a LAT-1 specific inhibitor in retinal pigment epithelial cells in vitro

    To investigate whether aldosterone (ALD) and hydrocortisone (HC) change the gene expression of SLC7A5, which encodes the large neutral amino acid...

    Norihiko Misawa, Shigeru Honda in Scientific Reports
    Article Open access 27 December 2023
  5. Predicting retinal pigment epithelium remodelling and its functional impact

    Purpose

    To identify predictive factors for RPE tear remodelling and its correlation with functional and morphological outcomes.

    Methods ...
    Rodrigo Vilares-Morgado, Carolina Madeira, ... Ângela Carneiro in Graefe's Archive for Clinical and Experimental Ophthalmology
    Article 02 March 2021
  6. Automated evaluation of retinal pigment epithelium disease area in eyes with age-related macular degeneration

    The retinal pigment epithelium (RPE) is essential for the survival and function of retinal photoreceptor cells. RPE dysfunction causes various...

    Naohiro Motozawa, Takuya Miura, ... Michiko Mandai in Scientific Reports
    Article Open access 18 January 2022
  7. Epidemiology of Mutations in the 65-kDa Retinal Pigment Epithelium (RPE65) Gene-Mediated Inherited Retinal Dystrophies: A Systematic Literature Review

    Introduction

    Inherited retinal dystrophies (IRDs) represent a genetically diverse group of progressive, visually debilitating diseases. Adult and...

    Juliana M. F. Sallum, Vinay Preet Kaur, ... M. Dominik Fischer in Advances in Therapy
    Article Open access 30 January 2022
  8. TNFα induced by DNA-sensing in macrophage compromises retinal pigment epithelial (RPE) barrier function

    Increasing evidence suggests that chronic inflammation plays an important role in the pathogenesis of age-related macular degeneration (AMD);...

    Michael Twarog, Joshua Schustak, ... Yi Bao in Scientific Reports
    Article Open access 02 September 2023
  9. Acute Retinal Pigment Epitheliitis

    Acute retinal pigment epitheliitis is a rare, idiopathic, self-limited inflammatory condition of the outer retina and retinal pigment epithelium of...
    Albert T. Vitale, Christopher D. Conrady in Uveitis
    Chapter 2021
  10. Boundary-Repairing Dual-Path Network for Retinal Layer Segmentation in OCT Image with Pigment Epithelial Detachment

    Automatic retinal layer segmentation in optical coherence tomography (OCT) images is crucial for the diagnosis of ocular diseases. Currently,...

    **aoming Liu, **ao Li, ... **shan Tang in Journal of Imaging Informatics in Medicine
    Article 13 May 2024
  11. Acute retinal pigment epitheliitis, a diagnostic myth?

    Mays Al-Nofal, Peter Charbel Issa in Eye
    Article Open access 02 August 2023
  12. Small Noncoding RNA in Regulation of Differentiation of Retinal Pigment Epithelium

    Abstract

    Dedifferentiation and epithelial-mesenchymal transition (EMT) of human retinal pigment epithelial (RPE) cells, as well as the participation...

    A. V. Kuznetsova, L. A. Rzhanova, M. A. Aleksandrova in Russian Journal of Developmental Biology
    Article 01 July 2021
  13. A novel miR-338-3p/SLC1A5 axis reprograms retinal pigment epithelium to increases its resistance to high glucose-induced cell ferroptosis

    Background

    Oxidative stress-induced cell ferroptosis occurs during the pathogenesis of diabetic retinopathy (DR), but the detailed molecular...

    **g Zhou, Caoyu Sun, ... Hui Wang in Journal of Molecular Histology
    Article 23 March 2022
  14. Characteristics of retinal pigment clumps in Type 2 macular telangiectasia (MacTel)

    Objective

    To assess the relationship of retinal pigment clump (RPC) size and its location with visual acuity and retinal neovascularisation in eyes...

    Ramesh Venkatesh, Sameeksha Agrawal, ... Jay Chhablani in Eye
    Article 14 April 2022
  15. Acute retinal pigment epitheliitis is not a diagnostic myth

    Giuseppe Casalino, Francesco Viola in Eye
    Article 15 November 2023
  16. Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic and non-diabetic retinopathy: associated factors and anatomical correlation

    Background

    This study aims to investigate the factors affecting the vitreous levels of pigment epithelium-derived factor (PEDF) and vascular...

    Rami Al-Dwairi, Tamam El-Elimat, ... Mohammed Allouh in International Journal of Retina and Vitreous
    Article Open access 21 May 2024
  17. Evaluation of retinal pigment epithelium changes in serous pigment epithelial detachment in age-related macular degeneration

    The purpose of this study was to quantitatively evaluate retinal pigment epithelium (RPE) changes in serous pigment epithelial detachment (PED) among...

    Masahiro Miura, Shuichi Makita, ... Tatsuo Yamaguchi in Scientific Reports
    Article Open access 02 February 2021
  18. Deficiency of thyroid hormone receptor protects retinal pigment epithelium and photoreceptors from cell death in a mouse model of age-related macular degeneration

    Age-related macular degeneration (AMD) is the leading cause of vision loss in the elderly. Progressive dystrophy of the retinal pigment epithelium...

    Hongwei Ma, Fan Yang, **-Qin Ding in Cell Death & Disease
    Article Open access 21 March 2022
  19. Retinal Detachment

    Detachment of the retina signifies an inward separation of the sensory part of the retina from the retinal pigment epithelium (RPE). There is an...
    Nicholas R. Galloway, Winfried M. K. Amoaku, ... Andrew C. Browning in Common Eye Diseases and their Management
    Chapter 2022
  20. Differential distribution of steroid hormone signaling networks in the human choroid-retinal pigment epithelial complex

    Background

    The retinal pigment epithelium (RPE), a layer of pigmented cells that lies between the neurosensory retina and the underlying choroid,...

    Sydney M. Galindez, Andrew Keightley, Peter Koulen in BMC Ophthalmology
    Article Open access 20 October 2022
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