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Posterior reversible encephalopathy syndrome: a rare cause of seizures following non-transplant cardiac surgery
Posterior reversible encephalopathy syndrome (PRES) is rarely reported as a cause for seizures following cardiac surgery. PRES in non-transplant...
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Pharmacotherapy for Seizures in Tuberous Sclerosis Complex
Epilepsy is one of the main symptoms affecting the lives of individuals with tuberous sclerosis complex (TSC), causing a high rate of morbidity....
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Depression, anxiety, stress, and suicide risk in patients with functional seizures vs. those with epilepsy
BackgroundWe aimed to investigate the rates of positive screening for depression, anxiety, stress, and suicide risk in adults with seizures [i.e.,...
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Clinical Characteristics and Prognostic Significance of Subclinical Seizures in Focal Epilepsy: A Retrospective Study
IntroductionThe aim was to evaluate the clinical characteristics and prognostic significance of subclinical seizures (SCSs) on scalp...
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Discrete subicular circuits control generalization of hippocampal seizures
Epilepsy is considered a circuit-level dysfunction associated with imbalanced excitation-inhibition, it is therapeutically necessary to identify key...
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Dominant, Non-lesional Frontal and Parietal Lobe Epilepsy
This chapter describes a patient with pharmacoresistant non-lesional focal epilepsy who underwent partial precuneus resection and multiple subpial... -
Neuroprotective effects of naltrexone in a mouse model of post-traumatic seizures
Traumatic Brain Injury (TBI) induces neuroinflammatory response that can initiate epileptogenesis, which develops into epilepsy. Recently, we...
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Seizures in a Child After Caudal Block for Circumcision
This is a case of postoperative seizures in an infant after circumcision. The case stem follows a routine anesthetic with standard medications and... -
Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures
Absence seizures are brief episodes of impaired consciousness, behavioral arrest, and unresponsiveness, with yet-unknown neuronal mechanisms. Here we...
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Evaluation and Management of New Onset and Breakthrough Seizures in Adults in the Emergency Department
Purpose of ReviewThis review seeks to inform ED providers about best practices in the evaluation and treatment of new onset seizures in adults as...
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Seizures in adults with suspected central nervous system infection
BackgroundSeizures can be part of the clinical presentation of central nervous system (CNS) infections. We describe patients suspected of a...
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Neuromonitoring in neonatal critical care part I: neonatal encephalopathy and neonates with possible seizures
AbstractThe blooming of neonatal neurocritical care over the last decade reflects substantial advances in neuromonitoring and neuroprotection. The...
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New GABA-Targeting Therapies for the Treatment of Seizures and Epilepsy: II. Treatments in Clinical Development
The inhibitory neurotransmitter γ-aminobutyric acid (GABA) plays an important role in the modulation of neuronal excitability, and a disruption of...
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Vagus Nerve Stimulation for Intractable Seizures
Vagus nerve stimulation (VNS) is the most widely used non-pharmacological treatment for drug-resistant epilepsy (DRE) since its approval by the FDA... -
Practical Approaches to the Treatment of Neonatal Seizures
Purpose of reviewThis paper critically reviews the current literature and evidence on diagnosis, classification, clinical approach, and management of...
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Morphometric correlates in patients with functional seizures with and without comorbid epilepsy
ObjectiveFunctional seizures (FS) or psychogenic, non-epileptic seizures (PNES) are episodic alterations of behaviour with similar semiology to...
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Clinical and laboratory characteristics of complex febrile seizures in the acute phase: a case-series study in Japan
BackgroundPatients with complex febrile seizures (CFS) often display abnormal laboratory results, unexpectedly prolonged seizures, and/or altered...
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Focal seizures during adrenocorticotropic hormone therapy in a school-aged boy: a case report
BackgroundAdrenocorticotropic hormone therapy for infantile spasms, including West syndrome, has been previously reported to induce seizures. We...
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Generalized absence seizures: Where do we stand today?
Generalized absence seizures are discussed here with respect to changing scientific concepts and newer findings, challenging the strict dichotomy of...
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Safety and Efficacy of Cenobamate for the Treatment of Focal Seizures in Older Patients: Post Hoc Analysis of a Phase III, Multicenter, Open-Label Study
BackgroundCenobamate is an antiseizure medication (ASM) approved in the US and Europe for the treatment of uncontrolled focal seizures.
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