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MRI features of benign peripheral nerve sheath tumors: how do sporadic and syndromic tumors differ?
ObjectivesTo compare MRI features of sporadic and neurofibromatosis syndrome–related localized schwannomas and neurofibromas.
Methods ...
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Correlation between imaging and histology in benign solitary retroperitoneal nerve sheath tumors: a pictorial review
BackgroundBenign nerve sheath tumors presenting as solitary retroperitoneal masses (RBNSTs) pose a complex diagnostic challenge for multidisciplinary...
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Chromosomal translocations inactivating CDKN2A support a single path for malignant peripheral nerve sheath tumor initiation
Malignant peripheral nerve sheath tumors (MPNST) are aggressive soft tissue sarcomas with poor prognosis, develo** either sporadically or in...
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Peripheral nerve sheath tumor: differentiation of malignant from benign tumors with conventional and diffusion-weighted MRI
ObjectivesTo evaluate potential of conventional MRI and diffusion-weighted imaging (DWI) for differentiating malignant from benign peripheral nerve...
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Systemic Options for Malignant Peripheral Nerve Sheath Tumors
Malignant peripheral nerve sheath tumors (MPNSTs) are rare mesenchymal neoplasms that represent a profound therapeutic challenge due to their high...
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Unusual Presentation of Malignant Peripheral Nerve Sheath Tumour of Mandible as a Colossal Tumour After Neoadjuvant Chemotherapy
The uniqueness of this case is the presentation of malignant peripheral nerve sheath tumors arising from the mandible as a colossal tumor of size of...
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Diagnostic potential of NRG1 in benign nerve sheath tumors and its influence on the PI3K-Akt signaling and tumor immunity
ObjectiveBenign nerve sheath tumors (BNSTs) present diagnostic challenges due to their heterogeneous nature. This study aimed to determine the...
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Extra-Anatomical Venous Bypass Through a Malignant Tumor for Palliation of Massive Arm Edema
A man in his early 40s presented with severe edema of his right upper extremity caused by a malignant peripheral nerve sheath tumor of the brachial...
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Enhancer reprogramming in PRC2-deficient malignant peripheral nerve sheath tumors induces a targetable de-differentiated state
Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that frequently harbor genetic alterations in polycomb repressor complex 2...
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Establishment and genomic characterization of a sporadic malignant peripheral nerve sheath tumor cell line
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive Schwann cell-derived neoplasms that occur sporadically or in patients with...
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Malignant Triton Tumor
Malignant Triton tumor is a variant of malignant peripheral nerve sheath tumor characterized by a rhabdomyoblastic cell component and a more...
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Epidemiology of Peripheral Nerve Sheath Tumors
Peripheral nerve sheath tumors (PNSTs) were first reported over 200 years ago. Since that time, our understanding of their epidemiological...
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Incidence and prognosis of distant metastasis in malignant peripheral nerve sheath tumors
BackgroundMalignant peripheral nerve sheath tumors (MPNSTs) are a type of soft tissue sarcomas (STS) with recurrence and metastatic potential. We...
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Spontaneous malignant transformation of trigeminal schwannoma: consideration of responsible gene alterations for tumorigenesis—a case report
Malignant peripheral nerve sheath tumors (MPNSTs) arising from the trigeminal nerves are extremely rare (only 45 cases, including the present case,...
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Managing Complications Related to Peripheral Nerve Surgery: Selected Illustrative Cases
Peripheral nerve surgery mostly involves elective procedures; thus, the associated complications are of great clinical, social, and medicolegal...
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Synovial sarcoma of the tibial nerve - case report of a rare tumor in a rare location requiring early diagnosis
BackgroundWe present the case of a patient with a rare synovial sarcoma (SS) of the tibial nerve. So far, only 4 cases of patients with SS...
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Management of Paraspinal Nerve Sheath Tumors
Paraspinal nerve sheath tumors are defined as neoplasms lateral to the neural foramen, originating from the nerve sheath, sometimes with significant...
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Incidentalomas of Spine and Peripheral Nervous System
Peripheral nerve sheath tumors (PNSTs) are a subset of neuroepithelial tumors characterized by their location involving multiple nerves. This chapter...
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Assessment of H3K27me3 immunohistochemistry and combination of NF1 and p16 deletions by fluorescence in situ hybridization in the differential diagnosis of malignant peripheral nerve sheath tumor and its histological mimics
BackgroundA definitive diagnosis of malignant peripheral nerve sheath tumor (MPNST) is challenging, especially in cases without neurofibromatosis 1...
