Abstract
The uniqueness of this case is the presentation of malignant peripheral nerve sheath tumors arising from the mandible as a colossal tumor of size of about 28 cm and weight of 1.5 kg after the first cycle of neoadjuvant chemotherapy. Role of neoadjuvant chemotherapy remains controversial and can be avoided if margin negative resection is feasible.
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Abbreviations
- MPNST:
-
Malignant peripheral nerve sheath tumors
- NF1:
-
Neurofibromatosis 1
- NACT:
-
Neoadjuvant chemotherapy
- IHC:
-
Immunohistochemistry
- CT:
-
Computed tomography
- LR:
-
Local recurrence
- OS:
-
Overall survival
- DM:
-
Distant metastasis
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All authors contributed to the study conception and design. Material preparation was performed by Dipin and Priyank Rathod. The first draft of the manuscript was written by Dipin. All authors read and approved the final manuscript.
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Jayaprakash, D., Rathod, P., Bhatt, S. et al. Unusual Presentation of Malignant Peripheral Nerve Sheath Tumour of Mandible as a Colossal Tumour After Neoadjuvant Chemotherapy. Indian J Otolaryngol Head Neck Surg 74 (Suppl 3), 5893–5896 (2022). https://doi.org/10.1007/s12070-021-02477-0
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DOI: https://doi.org/10.1007/s12070-021-02477-0