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Tetrachloromethane Induced Acute Liver Injury in Mice: Biochemical and Histopathological Study of the Hepatoprotective Effect of Hep-X Standardized Botanical Dietary Supplement
This work was aimed at investigating the hepatoprotective effect of Hep-X, a polyherbal formulation containing Silybum marianum L. (Milk thistle), Rosm...
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Enhanced bioavailability and hepatoprotective effect of silymarin by preparing silymarin-loaded solid dispersion formulation using freeze-drying method
This study aimed to develop a solid dispersion formulation of silymarin (Silymarin-SD) using freeze-drying method to enhance its oral bioavailability...
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Anti-Inflammatory, Wound Healing, and Hepatoprotective Effects of Ethanol Extract of Rice Bran in Rodent Models
Rice bran is an essential co-product in rice meals with many biological activities. This study was aimed at evaluating the anti-inflammatory, wound...
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Polypogon monspeliensis Hepatoprotective Attributes: UHPLC/QTOF-MS/MS Metabolite Profiling and In Vitro and In Silico Studies
Polypogon monspeliensis (L.) Desf. is an annual monocot weed belonging to Poaceae family, with reported folkloric medicinal uses. In this work, the...
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High-Performance Thin-Layer Chromatography Fingerprinting Analysis and Hepatoprotective Effects of Scrophularia striata Aerial Parts Against Acetaminophen-Induced Acute Hepatotoxicity in Mice
The liver performs detoxification, making it vulnerable to damage by common hepatotoxic medicines such as acetaminophen. Finding new medicines to...
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Hepatoprotective Efficacy of a New Phytocomposition of Essential Phospholipids with Glycyrrhizic Acid, Ecdysterone, and Lycopene in Experimental Chronic Hepatitis Compared to Phosphogliv
A phytocomposition of soy lecithin, glycyrrhizic acid, lycopene, and ecdysterone (conventional name Hepalipin) significantly prevents the development...
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Acute and Subchronic Oral Toxicity Study of a Hepatoprotective Polyherbal Formulation āLiver Capsuleā in Rats
A liver capsule is a hepatoprotective polyherbal formulation that has been traditionally used for the treatment of various diseases, particularly...
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Hepatoprotective Bile Acid Co-Drug of Isoniazid: Synthesis, Kinetics and Investigation of Antimycobacterial Potential
The long-course treatment of tuberculosis with isoniazid (INH) leads to hazardous side effects on liver and poor patient compliance. To overcome...
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Hepatoprotective and Antioxidant Activity of 8,8-Dimethyl-5-P-Tolyl-3,4,7,8-Tetrahydro-2H-Pyrido[4,3,2-de]Cinnolin-3-One
The hepatoprotective activity of 8,8-dimethyl-5- p -tolyl-3,4,7,8-tetrahydro-2 H -pyrido[4,3,2- de ]cinnolin-3-one was studied in vivo using a model of CCl 4 ...
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Assessment of the Pharmacological Activity of Aesculus hippocastanum L. Polysaccharides
This article reports studies of the biological activity of polysaccharides from aqueous and alkaline fractions isolated from the seed coats of the...
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Phenolic Contents, Enzyme Inhibitory Activities, and Protective Effect of Aqueous Extract of Rosa Pisiformis Fruits
The present study was designed to assess the phytochemical contents as well as the in vitro biological activities fruit of Rosa pisiformis and...
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Role of Berberis SSP and Acetaminophen-Induced Acute Liver Injury
Medicinal plants are an influential source of antioxidants and the hepatoprotective effects of some of them are well established. The antioxidant...
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Protective Effect of Ellagic Acid on Induced Liver Injury
The application of one of the most important nonsteroidal anti-inflammatory drugs, diclofenac, has been restricted due to its hepatotoxicity. The...
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Ameliorative Effect of Polysaccharide Rich Fraction from Eulophia herbacea Against Methotrexate Induced Liver Damage in Rats
The present study was aimed to investigate a protective effect of polysaccharide rich fraction from Eulophia herbacea Lindl. tubers against...
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The Ameliorative Effect of Monomethyl Fumarate and Silymarin Against Valproic Acid Induced Hepatotoxicity in Rats
Valproic acid (VPA) is a widely-used antiepileptic drug that has been extensively reported to cause hepatotoxicity. Monomethyl fumarate (MMF) is a...
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CoQ10 exerts hepatoprotective effect in fructose-induced fatty liver model in rats
BackgroundExcess dietary sugar is associated with deleterious metabolic effects, liver injury, and coenzyme-Q10 (CoQ10) deficiency. This study...
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Comparative Study of the Pharmacological Activity of Common Chicory Extracts
The pharmacological activities of wild common chicory herb extract and cultivated chicory leaf extract were compared to reveal promising sources of...
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Recent Advances in the Pharmacological Properties and Molecular Mechanisms of Carvacrol
Plant secondary metabolites have received a lot of attention for their immense pharmacological activities and low side effects. Monoterpenes,...
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Regulation of NOX/p38 MAPK/PPARĪ± pathways and miR-155 expression by boswellic acids reduces hepatic injury in experimentally-induced alcoholic liver disease mouse model: novel mechanistic insight
Alcoholic liver disease (ALD) refers to hepatic ailments induced by excessive alcohol intake. The pathogenesis of ALD comprises a complex interplay...
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Study of the Immunomodulatory Effect of Polysaccharides Isolated from Seeds of Turnip BRASSICA RAPA
The goal of this study was an evaluation of the immunomodulatory effect of polysaccharides isolated from the seeds of Brassica rapa . Apolysaccharide...
