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Treat borderline personality disorder with psychotherapy and concomitant psychiatric disorders with adjuvant pharmacotherapy
No class of medications has consistently improved symptoms of borderline personality disorder (BPD) in randomized clinical trials, and no...
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Medicinal Angiosperms of Campanulaceae, Lobeliaceae, Boraginaceae
This chapter introduces 30 species of medicinal plants in three families, mainly including, Adenophora divaricata, Adenophora hunanensis, Adenophora...
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Pharmacological Activities and Pharmacokinetics of Glycycoumarin
Glycycoumarin is a representative coumarin compound with significant pharmacological activities isolated from Glycyrrhiza uralensis Fisch., Fabaceae....
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Dextromethorphan/bupropion in major depressive disorder: a profile of its use
Dextromethorphan/bupropion (AUVELITY ® ), an oral, fixed-dose combination of dextromethorphan hydrobromide and bupropion hydrochloride, is a useful...
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Can research on entactogens contribute to a deeper understanding of human sexuality?
In recent years, scientific research into the therapeutic potential of psychedelic compounds has experienced a resurgence of interest. New studies...
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Medicinal Angiosperms of Liliaceae
This chapter introduces 69 species of medicinal plants in 1 family, mainly including Aletris laxiflora, Aletris pauciflora var. khasiana, Aletris...
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Morphological changes in spleen after dietary zinc deficiency and supplementation in Wistar rats
BackgroundStudy was conducted to determine the effect of dietary zinc deficiency and supplementation on the spleen morphology.
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Assessment of metabolic and hormonal profiles and striatal dopamine D2 receptor expression following continuous or scheduled high-fat or high-sucrose diet in rats
BackgroundObesity has reached global epidemic proportions and is associated with serious medical comorbidities and economic consequences. In this...
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Magnesium in schizophrenia
Many psychopathological symptoms, including schizophrenia, can be associated with magnesium metabolism disturbances. In the literature, contradictory...
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Naltrexone ER/bupropion ER in obesity management: a guide to its use
Oral naltrexone extended-release/bupropion extended-release (naltrexone ER/bupropion ER; Contrave ® , Mysimba™) is an effective adjunct to...
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Anticancer activities of some newly synthesized pyrazole and pyrimidine derivatives
A series of pyrazolopyridine and pyridopyrimidine derivatives 2 – 6 were newly synthesized using 3,5-bisarylmethylene-1-methylpiperidone as the...
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Attenuation of stress-induced behavioral deficits by lithium administration via serotonin metabolism
BackgroundAlthough the mood stabilizing role of lithium is well established and the cognitive effects of lithium are also best demonstrated, but its...
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Synthesis and neuromodulatory effects of TRH-related peptides: inhibitory activity on catecholamine release in vitro
BackgroundA detailed comprehension of central mechanisms underlying feeding behavior holds considerable promise for the treatment of alimentary...
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Behavioral deficits and exaggerated feedback control over raphe-hippocampal serotonin neurotransmission in restrained rats
Serotonin (5-hydroxytryptamine, 5-HT), acting via the hippocampus, is thought to be critical for the neuroadaptation that alleviates the adverse...
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Differences between human wild-type and C23S variant 5-HT2C receptors in inverse agonist-induced resensitization
The aim of this study was to analyze functional properties of the naturally occurring C23S variant of the human 5-HT2C receptor. In HEK293 cells...
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Successful Smoking Cessation
Tobacco use will kill as many as 1 billion people in the 21st century unless its use is curtailed. Smoking cessation is associated with several...
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