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Fertility issues in hypopituitarism
Women with hypopituitarism have lower fertility rates and worse pregnancy outcomes than women with normal pituitary function. These disparities exist...
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Hypopituitarism and bone disease: pathophysiology, diagnosis and treatment outcomes
Hypopituitarism is a rare but significant endocrine disorder characterized by the inadequate secretion of one or more pituitary hormones. The...
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Progress, challenges and perspectives in the management of hypopituitarism
Hypopituitarism is a rare endocrine disorder characterized by insufficient hormone secretion from the pituitary gland. This condition leads to...
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Diagnosing and treating the elderly individual with hypopituitarism
Hypopituitarism in the elderly is an underestimated condition mainly due to the non-specific presentation that can be attributed to the effects of...
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Morbidities and mortality among hospitalized patients with hypopituitarism: Prevalence, causes and management
Hypopituitarism is a highly heterogeneous multisystem disorder that can have a major impact on long-term morbidity and mortality, but even more so...
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Recognition and Practice of Hypopituitarism After Traumatic Brain Injury and Subarachnoid Hemorrhage in Japan: A Survey
IntroductionIndividuals with traumatic brain injury (TBI) or subarachnoid hemorrhage (SAH) are at a high risk of hypopituitarism, and should benefit...
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Hypoprolactinemia. Does it matter? Redefining the hypopituitarism and return from a mumpsimus
Prolactin (PRL) is secreted by the lactotroph cells in the anterior pituitary gland which is under inhibitory control of dopamine. The mature human...
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Partial hypopituitarism with ACTH deficiency as the main manifestation as a complication of hemorrhagic fever with renal syndrome
Hypopituitarism is a relatively rare complication of hemorrhagic fever with renal syndrome. However, almost all available reported cases were total...
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Three cases of immune-related hypopituitarism after atezolizumab–bevacizumab treatment for hepatocellular carcinoma
We herein report three cases of immune-related hypopituitarism after atezolizumab–bevacizumab treatment for hepatocellular carcinoma (HCC). Case 1...
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Diagnosis and therapeutic approach to bone health in patients with hypopituitarism
The results of many studies in recent years indicate a significant impact of pituitary function on bone health. The proper function of the pituitary...
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Pitfalls in the lab assessment of hypopituitarism
The diagnostic approach to hypopituitarism involves many disciplines. Clinical symptoms rarely are specific. Imaging techniques are helpful but...
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Hypopituitarism with secondary adrenocortical insufficiency and arginine vasopressin deficiency due to hypophysitis after COVID-19 vaccination: a case report
BackgroundAlthough vaccination against coronavirus disease (COVID-19) has several side effects, hypopituitarism due to hypophysitis has rarely been...
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Uncovering the link between celiac disease and hypopituitarism: a case report and review of literature
BackgroundCeliac disease, an autoimmune condition triggered by gluten-containing diet, is known to primarily manifest as intestinal symptoms, but can...
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Hypereosinophilia is a predictive biomarker of immune checkpoint inhibitor-induced hypopituitarism in patients with renal cell carcinoma
BackgroundThis study aimed to evaluate whether hypereosinophilia is a clinical biomarker of immune checkpoint inhibitor-induced hypopituitarism in...
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COVID-19 and hypopituitarism
Besides the pulmonary manifestations caused by severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), an emerging endocrine phenotype,...
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Effect of distance from target on hypopituitarism after stereotactic radiosurgery for pituitary adenomas
IntroductionDelayed hypopituitarism is the most common complication after stereotactic radiosurgery (SRS) for pituitary adenomas. The aim of this...
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Congenital hypopituitarism and multiple midline defects in a newborn with non-familial Cat Eye syndrome
BackgroundCat eye syndrome (CES) is a rare chromosomal disease, with estimated incidence of about 1 in 100,000 live newborns. The classic triad of...
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Hypopituitarism and cranial nerve involvement mimicking Tolosa-Hunt syndrome as the initially presenting feature of diffuse large B-cell lymphoma: a case report
BackgroundEarly diagnosis of lymphoma involving the central nervous system is sometimes difficult but emergent to avoid the delay of therapeutic...
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A long-term survival case with proton beam therapy for advanced sphenoid sinus cancer with hypopituitarism
Sphenoid sinus malignancies are rare diseases. Secondary hypopituitarism associated with sphenoid sinus malignancy is not well known. A 41-year-old...
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Idiopathic central diabetes insipidus in a large cohort of patients: the hypopituitarism ENEA rare observational (HEROS) study
Central Diabetes Insipidus (CDI) is mainly associated with structural pathologies of the hypothalamic-pituitary area. Etiologies underlying CDI are...
