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Reliability of predicting low-burden (≤ 2) positive axillary lymph nodes indicating sentinel lymph node biopsy in primary operable breast cancer — a retrospective comparative study with PET/CT and breast MRI
BackgroundSentinel lymph node biopsy (SLNB) is the standard of care for axillary staging in early breast cancer patients with low-burden axillary...
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A Novel Injection Protocol Using Voluven®-Assisted Indocyanine Green with Improved Near-Infrared Fluorescence Guidance in Breast Cancer Sentinel Lymph Node Map**—A Translational Study
BackgroundNear-infrared (NIR) fluorescence-guided surgery with indocyanine green (ICG) has been demonstrated to provide high sensitivity in sentinel...
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Comparison of two hybrid sentinel node tracers: indocyanine green (ICG)-99mTc-nanocolloid vs. ICG-99mTc-nanoscan from a nuclear medicine and surgical perspective
BackgroundLymph node (LN) metastasis is a relevant predictor for survival in patients with a.o. penile cancer (PeCa), malignant melanoma. The...
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Single-port three-dimensional (3D) endoscopic-assisted breast surgery—preliminary results and patient-reported satisfaction in 145 breast cancer and gynecomastia cases
BackgroundMinimal-accessed (robotic and endoscopic) breast cancer surgery is increasingly performed due to better cosmetic results and acceptable...
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Extracellular vesicle-mediated drug delivery in breast cancer theranostics
Breast cancer (BC) continues to be a significant global challenge due to drug resistance and severe side effects. The increasing prevalence is...
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Comparison of wire-guided localization (WGL) and radio-guided occult lesion localization (ROLL) in localization of non-palpable breast lesions
BackgroundThe number of patients with non-palpable breast lesions has increased gradually. This is because of the technological development in...
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Use of 125 iodine seeds for intra-operative localization of nonpalpable breast lesions (ROLLIS): analysis of the implant of 1757 seeds in 1477 patients
ObjectiveTo analyze the feasibility, efficacy and results of the use of 125Iodine seeds for intra-operative localization of nonpalpable breast...
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Evaluation of camera-based freehand SPECT in preoperative sentinel lymph node map** for melanoma patients
BackgroundAssessment of lymphatic status via sentinel lymph node (SLN) biopsy is an integral and crucial part of melanoma surgical oncology. The most...
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Smart nanoparticles for cancer therapy
Smart nanoparticles, which can respond to biological cues or be guided by them, are emerging as a promising drug delivery platform for precise cancer...
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Lymphadenectomy in Endometrial Cancers—A Review
Most endometrial cancers are diagnosed in an early stage, and nearly three-fourths do not require any lymph node clearance. Surgical staging is...
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Diagnostic modalities and radiopharmaceuticals with particular importance of technetium-99m (99mTc)
With the emergence of new diseases, a lot of advancements have been made in diagnosis such as identification of new biomarkers, imaging techniques,...
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Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology
BackgroundRecent advances in nanotechnology have offered new hope for cancer detection, prevention, and treatment. Nanomedicine, a term for the...
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Multifunctional mesoporous silica nanoparticles for biomedical applications
Mesoporous silica nanoparticles (MSNs) are recognized as a prime example of nanotechnology applied in the biomedical field, due to their easily...
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A Novel Indocyanine Green Fluorescence-Guided Video-Assisted Technique for Sentinel Node Biopsy in Breast Cancer
BackgroundThe equipment to detect indocyanine green (ICG) fluorescence for sentinel lymph node (SLN) biopsy in breast cancer is not widely accessible...
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Systematic imaging in medicine: a comprehensive review
Systematic imaging can be broadly defined as the systematic identification and characterization of biological processes at multiple scales and...