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Reduction of false positives using zone-specific prostate-specific antigen density for prostate MRI-based biopsy decision strategies
ObjectivesTo develop and test zone-specific prostate-specific antigen density (sPSAD) combined with PI-RADS to guide prostate biopsy decision...
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Fipronil disturbs the antigen-specific immune responses and GABAergic gene expression in the ovalbumin-immunized BALB/c mice
BackgroundFipronil (FPN) is a broad-spectrum pesticide and commonly known as low toxicity to vertebrates. However, increasing evidence suggests that...
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Prostate-specific membrane antigen radioguided surgery with negative histopathology: an in-depth analysis
PurposeTo identify reasons for negative histopathology of specimens from prostate-specific membrane antigen (PSMA) radioguided surgery (PSMA-RGS) in...
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Value of serum free prostate-specific antigen density in the diagnosis of prostate cancer
PurposeTo investigate the value of serum free prostate-specific antigen density (fPSAD) in the diagnosis of prostate cancer (PCa).
Methods ...
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Chronic lymphocytic leukemia presence impairs antigen-specific CD8+ T-cell responses through epigenetic reprogramming towards short-lived effectors
T-cell dysregulation in chronic lymphocytic leukemia (CLL) associates with low response rates to autologous T cell-based therapies. How CLL affects...
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Increase of prostate-specific antigen doubling time predicts survival in metastatic castration-resistant prostate cancer patients undergoing radium therapy
ObjectiveRadium-223 (Ra-223) is an important treatment modality for bone-dominant metastatic castration-resistant prostate cancer (mCRPC). However,...
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The effect of limited english proficiency on prostate-specific antigen screening in American men
PurposeTo evaluate how limited English proficiency (LEP) impacts the prevalence of prostate-specific antigen (PSA) screening in a contemporary,...
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Study of prostate-specific antigen levels during salvage radiotherapy after prostate cancer surgery
BackgroundAdministration of adjuvant or salvage radiotherapy (RT) after prostate cancer (PCa) surgery is supported by clinical evidence and is a...
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Prostate Specific Membrane Antigen Expression in a Syngeneic Breast Cancer Mouse Model
PurposeProstate specific membrane antigen (PSMA) has been studied in human breast cancer (BCa) biopsies, however, lack of data on PSMA expression in...
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Antigen specific T cells in people with obesity at five months following ChAdOx1 COVID-19 vaccination
Background/ObjectivesPeople with obesity (PWO) face an increased risk of severe outcomes from COVID-19, including hospitalisation, ICU admission and...
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Head-to-head comparison of prostate-specific membrane antigen PET and multiparametric MRI in the diagnosis of pretreatment patients with prostate cancer: a meta-analysis
ObjectivesTo compare prostate-specific membrane antigen (PSMA) PET with multiparametric MRI (mpMRI) in the diagnosis of pretreatment prostate cancer...
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Prostate-specific membrane antigen-positron emission tomography (PSMA-PET) of prostate cancer: current and emerging applications
Prostate-specific membrane antigen-positron emission tomography (PSMA-PET) is transforming the management of patients with prostate cancer. In...
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Persistent virus-specific and clonally expanded antibody-secreting cells respond to induced self-antigen in the CNS
B cells contribute to the pathogenesis of both cellular- and humoral-mediated central nervous system (CNS) inflammatory diseases through a variety of...
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Association of TyG index with prostate-specific antigen (PSA) in American men: results from NHANES, 2003–2010
BackgroundIn recent years, triglyceride-glucose index (TyG) was a new indicator of insulin resistance, and it has been widely reported that it may be...
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Interaction between drinking and dietary inflammatory index affects prostate specific antigen: a cross-sectional study
BackgroundNumerous studies have shown that the dietary inflammatory index (DII) is associated with adverse health effects. However, the relationship...
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Targeting FLT3-specific chimeric antigen receptor T cells for acute lymphoblastic leukemia with KMT2A rearrangement
CD19-specific chimeric antigen receptor T (CAR T) immunotherapy is used to treat B-cell malignancies. However, antigen-escape mediated relapse...
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Association between vitamin B2 intake and prostate-specific antigen in American men: 2003–2010 National Health and Nutrition Examination Survey
BackgroundAccumulating evidence suggests a pivotal role of vitamin B2 in the pathogenesis and progression of prostate cancer (PCa). Vitamin B2 intake...
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Delphi consensus project on prostate-specific membrane antigen (PSMA)–targeted surgery—outcomes from an international multidisciplinary panel
PurposeProstate-specific membrane antigen (PSMA) is increasingly considered as a molecular target to achieve precision surgery for prostate cancer. A...
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XFab-α4-1BB/CD40L fusion protein activates dendritic cells, improves expansion of antigen-specific T cells, and exhibits antitumour efficacy in multiple solid tumour models
BackgroundAdditional immunotherapies are still warranted for non-responders to checkpoint inhibitors with refractory or relapsing cancers, especially...
