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Design and Evaluation of a High-Precision Programmable Force-Sensing Therapeutic Intramyocardial Stem Cell Injection Device
Treating congestive heart failure by injecting potential cardio-reparative cells, such as mesenchymal stem cells (MSCs), into the myocardium via a...
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Fracture Failure Analysis of a High-Pressure Bypass Valve Stem
The high-pressure bypass valve stem of an ultra-supercritical unit has undergone a fatal fracture after running for more than 10,000 h. We analyzed...
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Classes of Stem Cells: From Biology to Engineering
PurposeThe majority of adult tissues are limited in self-repair and regeneration due to their poor intrinsic regenerative capacity. It is widely...
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Progress and emerging techniques for biomaterial-based derivation of mesenchymal stem cells (MSCs) from pluripotent stem cells (PSCs)
The use of mesenchymal stem cells (MSCs) for clinical purposes has skyrocketed in the past decade. Their multilineage differentiation potentials and...
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STEM High Angle Annular Dark-Field Imaging
High-angle annular dark field (HAADF) imaging in the aberration-corrected scanning transmission electron microscope (STEM) has become an invaluable... -
Reconstruction of ocular surfaces with limbal stem cells supported by porous composite hydrogels
Stem cell-based therapy is a novel technique used to reconstruct the ocular surface of patients with limbal stem cell deficiency (LSCD). However, the...
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Integrating Nanosensors into Stem Cells Technologies and Regenerative Medicine
This work explores the revolutionary potential that arises from combining nanosensors with stem cell technologies and regenerative medicine. The... -
Integrating Nanosensors into Stem Cells Technologies and Regenerative Medicine
This work explores the revolutionary potential that arises from combining nanosensors with stem cell technologies and regenerative medicine. The... -
Advanced Electrospun Nanofibrous Stem Cell Niche for Bone Regenerative Engineering
AbstractRegenerative engineering has converged the upward advancements of various scientific fields such as advanced material science, developmental...
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CRISPR/Cas9 assisted stem cell therapy in Parkinson's disease
Since its discovery in 2012, CRISPR Cas9 has been tried as a direct treatment approach to correct the causative gene mutation and establish animal...
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Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells
Therapeutic genome editing of haematopoietic stem cells (HSCs) would provide long-lasting treatments for multiple diseases. However, the in vivo...
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Reduced graphene oxide-mediated magnetoelectric effect drives neural differentiation of mesenchymal stem cells
Neurodegenerative illnesses are among the most difficult conditions to treat in humans. As mesenchymal stem cells (MSCs) are easily acquired for...
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Analysis of Stem Assembly of Inflatable Aerodynamic Decelerator (IAD) that Failed During Spin Test
Inflatable aerodynamic decelerators (IADs) are designed to slow down the speed of a spacecraft or payload during its descent through an atmosphere....
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Type I Collagen/Hyaluronic Acid Hydrogels as Delivery System for Adipose-Derived Stem Cells for Osteoarthritis Treatment
PurposeTo improve the efficacy of stem cell therapy in treating osteoarthritis, we developed a cell-protective and cell-supporting injectable...
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Three-dimensional reconstruction of Y-IrNi rhombic dodecahedron nanoframe by STEM/EDS tomography
The structural analysis of nanocrystals via transmission electron microscopy (TEM) is a valuable technique for the material science field. Recently,...
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A correlated ferromagnetic polar metal by design
Polar metals have recently garnered increasing interest because of their promising functionalities. Here we report the experimental realization of an...
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3D Spongin-Based Scaffolds from Marine Demosponge Haliclona sp. for Biomedical Engineering Approaches Based on Mesenchymal Stem Cells
BackgroundSpongin is a versatile organic protein derived from marine sponges, similar to collagen. It has high elasticity after hydration and is used...
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Bone Marrow Mesenchymal Stem Cells Expanded Inside the Nichoid Micro-Scaffold: a Focus on Anti-Inflammatory Response
PurposeMesenchymal stem cells (MSCs) represent a promising source for stem cell therapies in numerous diseases, including pediatric respiratory...
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Targeting triple negative breast cancer stem cells using nanocarriers
Breast cancer is a complex and heterogeneous disease, encompassing various subtypes characterized by distinct molecular features, clinical behaviors,...
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Exosomes derived from mir-214-3p overexpressing mesenchymal stem cells promote myocardial repair
AimsExosomes are known as nanovesicles that are naturally secreted, playing an essential role in stem-mediated cardioprotection. This study mainly...