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Zinc in Plants: Biochemical Functions and Dependent Signaling
Zinc is an essential micronutrient for plant growth and development. Zinc is involved in a wide variety of cellular processes, including...
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Neuronal Calcium Sensor-1: A Zinc/Redox-Dependent Protein of Nervous System Signaling Pathways
AbstractIntracellular calcium signaling is involved in regulating the key functional mechanisms of the nervous system. The control of neuronal...
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Dietary Zinc Ameliorates TNBS-Induced Colitis in Mice Associated with Regulation of Th1/Th2/Th17 Balance and NF-κB/NLRP3 Signaling Pathway
Inflammatory bowel diseases (IBDs), including Crohn’s disease and ulcerative colitis, are chronic relapsing inflammatory gastrointestinal tract...
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Elevated luteinizing hormone receptor signaling or selenium treatment leads to comparable changes in adrenal cortex histology and androgen-AR/ZIP9 signaling
The importance and regulation of adrenal androgen production and signaling are not completely understood and are scarcely studied. In addition, there...
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Zinc ions negatively regulate proapoptotic signaling in cells expressing oncogenic mutant Ras
Mutational activation of the Ras family of proto-oncogenes promotes cell survival and proliferation. Studies using cells cultured in vitro have shown...
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Zinc supplementation ameliorates sorafenib-induced cognitive impairment through ROS/JNK signaling pathway
Sorafenib, a multiple kinase inhibitor, is widely used in cancer patients. Recently, clinical studies highlighted the relationship between cognitive...
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The auxin signaling pathway contributes to phosphorus-mediated zinc homeostasis in maize
Although the interaction between P and Zn has long been recognized in plants, the physiological and molecular mechanisms underlying P and Zn...
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Zinc Ameliorates Tripterygium Glycosides–Induced Reproductive Impairment in Male Rats by Regulating Zinc Homeostasis and Expression of Oxidative Stress–Related Genes
Tripterygium glycosides (TG) can seriously damage male reproductive function, and the reproductive system is difficult to restore after stop** the...
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Serum Zinc Level and Efficacy of Zinc Therapy in Cutaneous Leishmaniasis: a Systematic Review and Meta-analysis
Cutaneous leishmaniasis is a parasitic skin disease prevalent in many parts of the world. Zinc has been investigated for its potential role in the...
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Effects of Zinc Combined with Metformin on Zinc Homeostasis, Blood-Epididymal Barrier, and Epididymal Absorption in Male Diabetic Mice
Diabetes increases the likelihood of germ cell damage, hypogonadism, and male infertility. Diabetes leads to lower zinc (Zn) levels, an important...
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Neurodevelopmental Consequences of Dietary Zinc Deficiency: A Status Report
Zinc is a tightly regulated trace mineral element playing critical roles in growth, immunity, neurodevelopment, and synaptic and hormonal signaling....
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The Role of Zinc Status on Spatial Memory, Hippocampal Synaptic Plasticity, and Insulin Signaling in icv-STZ-Induced Sporadic Alzheimer’s-Like Disease in Rats
Alzheimer’s disease (AD), especially its sporadic form (sAD), is of multifactorial nature. Brain insulin resistance and disrupted zinc homeostasis...
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Effect of Zinc Amino Acid Complexes on Growth Performance, Tissue Zinc Concentration, and Muscle Development of Broilers
The present study aimed to evaluate the effects of zinc amino acid complexes on growth performance, tissue zinc concentration, and muscle development...
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Signaling Pathways in Plant Responses to Abiotic Stress
Recent scientific advancements have significantly improved our understanding of plant signaling pathways under abiotic stress. However, further...
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Green Synthesized Zinc Oxide Nanoparticles Attenuate Acrylamide-Induced Cardiac Injury via Controlling Endoplasmic Reticulum Stress–Associated Apoptosis Through ATF3/CHOP/BCL2 Signaling in Rats
Due to their distinctive properties, several eco-friendly metal oxide nanoparticles were assessed for their possible cardioprotective properties....
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Dietary Zinc Supplementation in Steers Modulates Labile Zinc Concentration and Zinc Transporter Gene Expression in Circulating Immune Cells
Zinc (Zn) is critical for immune function, and marginal Zn deficiency in calves can lead to suboptimal growth and increased disease susceptibility....
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Cardiovascular Diseases and Zinc
Zinc is structurally and functionally essential for more than 300 enzymes and 2000 transcription factors in human body. Intracellular labile zinc is...
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Cell Signaling Response Under Plants Stress
Stresses (mechanical, herbivore, and insect damage) are the major threats that reduce plant yield and productivity. These stresses adversely modify...
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Metabolites of Chemical Signaling Pathways from Crop–Microbe Interactions
Crop–microbe interactions play an important role in plant growth, development, and health. These interactions are mediated by chemical signals, which...
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Zinc and Inflammatory Bowel Disease: From Clinical Study to Animal Experiment
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract (GI) with a high incidence rate globally, and IBD...
