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Improving the study of plant evolution with multi-matrix mixture models
Amino acid substitution model is a key component to study the plant evolution from protein sequences. Although single-matrix amino acid substitution...
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Bayesian multi-species N-mixture models for unmarked animal communities
We propose an extension of the N-mixture model that enables the estimation of abundances of multiple species as well as the correlations between...
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Bayesian N-Mixture Models Applied to Estimating Insect Abundance
Estimating animal abundance is an area of interest for many conservationists and population ecologists. When using count data to obtain abundance...
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Consensus clustering for Bayesian mixture models
BackgroundCluster analysis is an integral part of precision medicine and systems biology, used to define groups of patients or biomolecules....
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A clustering procedure for three-way RNA sequencing data using data transformations and matrix-variate Gaussian mixture models
RNA sequencing of time-course experiments results in three-way count data where the dimensions are the genes, the time points and the biological...
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Fitting Gaussian mixture models on incomplete data
BackgroundBioinformatics investigators often gain insights by combining information across multiple and disparate data sets. Merging data from...
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A model-based clustering via mixture of hierarchical models with covariate adjustment for detecting differentially expressed genes from paired design
The causes of many complex human diseases are still largely unknown. Genetics plays an important role in uncovering the molecular mechanisms of...
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Based on molecular docking and real-time PCR technology, the two-component system Bae SR was investigated on the mechanism of drug resistance in CRAB
This study aimed to explore the role of the two-component system Bae SR in the mechanism of drug resistance in carbapenem-resistant A. baumannii ...
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The Association Between Essential Metal Element Mixture and Sleep Quality in Chinese Community-Dwelling Older Adults
Previous studies have related single essential metal elements (EMEs) to sleep quality among older adults, however, the association of the EME mixture...
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Cooling of a granular gas mixture in microgravity
Granular gases are fascinating non-equilibrium systems with interesting features such as spontaneous clustering and non-Gaussian velocity...
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Molecular mechanism of siderophore regulation by the Pseudomonas aeruginosa BfmRS two-component system in response to osmotic stress
Pseudomonas aeruginosa , a common nosocomial pathogen, relies on siderophores to acquire iron, crucial for its survival in various environments and...
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Mixture models as a method for comparative sociality: social networks and demographic change in resident killer whales
AbstractIn studies of social behaviour, social bonds are usually inferred from rates of interaction or association. This approach has revealed many...
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Mixture density networks for the indirect estimation of reference intervals
BackgroundReference intervals represent the expected range of physiological test results in a healthy population and are essential to support medical...
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Characterization of Two-Component System gene (TCS) in melatonin-treated common bean under salt and drought stress
The two-component system ( TCS ) generally consists of three elements, namely the histidine kinase ( HK ), response regulator ( RR ), and histidine...
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ZINBMM: a general mixture model for simultaneous clustering and gene selection using single-cell transcriptomic data
Clustering is a critical component of single-cell RNA sequencing (scRNA-seq) data analysis and can help reveal cell types and infer cell lineages....
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Insight into the emerging and common experimental in-vivo models of Alzheimer’s disease
Alzheimer’s disease (AD) is a multifactorial, rapidly progressing neurodegenerative disorder. As the exact cause of the disease is still unclear, the...
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GMMchi: gene expression clustering using Gaussian mixture modeling
BackgroundCancer evolution consists of a stepwise acquisition of genetic and epigenetic changes, which alter the gene expression profiles of cells in...
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Bayesian Cross-Validation Comparison of Amino Acid Replacement Models: Contrasting Profile Mixtures, Pairwise Exchangeabilities, and Gamma-Distributed Rates-Across-Sites
Models of amino acid replacement are central to modern phylogenetic inference, particularly so when dealing with deep evolutionary relationships....
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Generalized Linear Models
In the generalized linear model (GLM) (which is not highly general) y = Xβ + ϵ, the response variables are normally distributed, with constant...
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The Effect of Mixture of Heavy Metals on Obesity in Individuals ≥50 Years of Age
Little is known about the association between a mixture of heavy metals and obesity among individuals ≥50 years of age with comorbidities. Thus, we...
