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Salivary gland transcriptome analysis in Hirudinaria sp. during different feeding periods and functional studies of HspHirudin
Hirudinaria sp., as one of the origins of leeches used in traditional Chinese medicine, was proved clinically effective in treating cardiovascular...
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Screening candidate effectors from the salivary gland transcriptomes of brown citrus aphid, Aphis citricidus
The brown citrus aphid, Aphis citricidus , stands out as an important citrus pest that is an efficient vector for Citrus tristeza virus (CTV), the...
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Retinoic acid and FGF10 promote the differentiation of pluripotent stem cells into salivary gland placodes
BackgroundSalivary glands produce saliva that play essential roles in digestion and oral health. Derivation of salivary gland organoids from...
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Stem Cell-Based Regeneration of Salivary Glands: From Bench to Clinics
Exocrine gland regeneration, particularly salivary gland regeneration, remains an exciting arena for the scientific world due to its crucial role in... -
Reversely immortalized mouse salivary gland cells presented a promising metabolic and fibrotic response upon BMP9/Gdf2 stimulation
The submandibular gland (SMG) and the sublingual gland (SLG) are two of the three major salivary glands in mammals. In mice, they are adjacent to...
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Stem Cell-Based Regeneration of Salivary Glands: From Bench to Clinics
Exocrine gland regeneration, particularly salivary gland regeneration, remains an exciting arena for the scientific world due to its crucial role in... -
Induction of Salivary Gland-Like Tissue by Induced Pluripotent Stem Cells In Vitro
Background:To investigate the in vitro induction of salivary gland-like tissue by ips cells in an interferon regulatory factor 6 (IRF6)...
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Stem Cell-Based Regeneration of Salivary Glands: From Bench to Clinics
Exocrine gland regeneration, particularly salivary gland regeneration, remains an exciting arena for the scientific world due to its crucial role in... -
Genomic and transcriptomic analyses support a silk gland origin of spider venom glands
BackgroundSpiders comprise a hyperdiverse lineage of predators with venom systems, yet the origin of functionally novel spider venom glands remains...
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Whole-body transcriptome mining for candidate effectors from Diuraphis noxia
BackgroundProteins within aphid saliva play a crucial role as the molecular interface between aphids and their host plants. These salivary effectors...
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Comparative transcriptomic analysis of salivary glands between the zoophytophagous Cyrtorhinus lividipennis and the phytozoophagous Apolygus lucorum
BackgroundSaliva plays a crucial role in sha** the feeding behavior of insects, involving processes such as food digestion and the regulation of...
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Protease-bound structure of Ricistatin provides insights into the mechanism of action of tick salivary cystatins in the vertebrate host
Tick saliva injected into the vertebrate host contains bioactive anti-proteolytic proteins from the cystatin family; however, the molecular basis of...
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Acid phosphatase-like proteins, a biogenic amine and leukotriene-binding salivary protein family from the flea Xenopsylla cheopis
The salivary glands of hematophagous arthropods contain pharmacologically active molecules that interfere with host hemostasis and immune responses,...
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Derivation of Human Salivary Epithelial Progenitors from Pluripotent Stem Cells via Activation of RA and Wnt Signaling
Derivation of salivary gland epithelial progenitors (SGEPs) from human pluripotent stem cells (hPSCs) has great potential in developmental biology...
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LC‒MS/MS and transcriptome analyses reveal saliva components of the seed-feeding truebug Pyrrhocoris apterus
Saliva secretion is essential for successful feeding by piercing–sucking insects. Despite extensive studies of the saliva composition of phloem- and...
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Elucidating the ecophysiology of soybean pod-sucking stinkbug Riptortus pedestris (Hemiptera: Alydidae) based on de novo genome assembly and transcriptome analysis
Food security is important for the ever-growing global population. Soybean, Glycine max (L.) Merr., is cultivated worldwide providing a key source of...
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RNA-seq coupling two different methods of castration reveals new insights into androgen deficiency-caused degeneration of submaxillary gland in male Sprague Dawley rats
BackgroundSalivary gland (SMG) degeneration and dysfunction are common symptoms that occur after sex hormone deprivation, but the underlying...
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Division of developmental phases of freshwater leech Whitmania pigra and key genes related to neurogenesis revealed by whole genome and transcriptome analysis
The freshwater leech Whitmania pigra ( W. pigra ) Whitman (Annelida phylum) is a model organism for neurodevelopmental studies. However, molecular...
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Comprehensive analysis of silk proteins and gland compartments in Limnephilus lunatus, a case-making trichopteran
Caddisfly larvae produce silk containing heavy and light fibroins, similar to the silk of Lepidoptera, for the construction of underwater structures....
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Transcriptomic and proteomic analysis of putative digestive proteases in the salivary gland and gut of Empoasca (Matsumurasca) onukii Matsuda
BackgroundInfestation by tea green leafhoppers ( Empoasca (Matsumurasca) onukii ) can cause a series of biochemical changes in tea leaves. As a...