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Variability of Multiple Resistance to Antibiotics in a Cholera Agent Associated with Different Types of SXT Element and Spontaneous Chromosome Mutations
The aim of the study is to analyze the variability of multiple antibiotic resistance caused by variations in the mobile SXT element and chromosomal...
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Azithromycin can induce SOS response and horizontal gene transfer of SXT element in Vibrio cholerae
BackgroundThe emergence and spread of drug resistance in Vibrio cholerae are mainly attributed to horizontal gene transfer of mobile genetic...
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Promoter regions of sxtA and sxtG reveal relationship between saxitoxin biosynthesis and photosynthesis in toxic Alexandrium catenella
The marine dinoflagellate Alexandrium catenella (Group I) produces saxitoxins (STXs) in marine environments, causing paralytic shellfish poisoning...
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DIVE: a reference-free statistical approach to diversity-generating and mobile genetic element discovery
Diversity-generating and mobile genetic elements are key to microbial and viral evolution and can result in evolutionary leaps. State-of-the-art...
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Genomic epidemiology reveals multidrug resistant plasmid spread between Vibrio cholerae lineages in Yemen
Since 2016, Yemen has been experiencing the largest cholera outbreak in modern history. Multidrug resistance (MDR) emerged among Vibrio cholerae ...
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Spectrum of ctxB genotypes, antibiogram profiles and virulence genes of Vibrio cholerae serogroups isolated from environmental water sources from Odisha, India
BackgroundThe present study reports on the comprehensive analysis of Vibrio cholerae O1 and non-O1/non-O139 serogroups isolated from environmental...
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Exploring the dynamics of toxigenic environmental Vibrio mimicus and its comparative analysis with Vibrio cholerae of the southern Gangetic delta
Vibrio mimicus and Vibrio cholerae are closely related species. Environmental V.mimicus were comparatively analyzed with V.cholerae , for the presence...
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Identification of metallo-β-lactamases and AmpC production among Escherichia coli strains isolated from hemodialysis patients with urinary tract infection
BackgroundThis study aimed to identify metallo-β-lactamases (MBLs) and AmpC β-lactamases-producing Escherichia coli isolates obtained from...
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Molecular Genetic Analysis of Vibrio cholerae O1 El Tor Strains Identified in 2023 in Russia
AbstractA comparative analysis of the genome of nontoxigenic and toxigenic V. cholerae O1 El Tor strains identified in Russia in 2023 and their...
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Genomic characterization of multi drug resistant ESBL-producing Escherichia coli isolates from patients and patient environments in a teaching hospital in Ghana
BackgroundESBL-producing Escherichia coli pose a growing health risk in community and healthcare settings. We investigated the resistome, virulome,...
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Cholera Dynamics and the Emergence of Pandemic Vibrio cholerae
Cholera is a severe diarrheal disease caused by the aquatic bacterium Vibrio cholerae. Interestingly, to date, only one major clade has emerged to...
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Interpretable machine learning-based decision support for prediction of antibiotic resistance for complicated urinary tract infections
Urinary tract infections are one of the most common bacterial infections worldwide; however, increasing antimicrobial resistance in bacterial...
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Mobile genetic elements used by competing coral microbial populations increase genomic plasticity
Intraspecies diversification and niche adaptation by members of the Vibrio genus, one of the most diverse bacterial genera, is thought to be driven...
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Genetic diversity of KPC-2-producing Klebsiella pneumoniae complex from aquatic ecosystems
During the COVID-19 pandemic, the occurrence of carbapenem-resistant Klebsiella pneumoniae increased in human clinical settings worldwide. Impacted...
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The rise of multidrug resistant Salmonella isolates in healthy chickens in Brazil by successful establishment of plasmid IncHI2A carrying several antibiotic resistance genes
Salmonella spp. is an important global issue in food-producing animals. The present study evaluated antimicrobial resistance and virulence profiles...
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Molecular Insights into Genomic Islands and Evolution of Vibrio cholerae
Vibrio cholerae is a Gram-negative, motile, slightly curved bacteria that produces an enterotoxin, resulting in a potentially fatal acute watery...
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Identification of two major direct repeat unit clusters, 8i and 11ce, among methicillin resistant Staphylococcus aureus strains: the emergence of novel dru types and repeats
BackgroundThe changing epidemiology and decreasing susceptibility to first-line antibiotics, such as vancomycin and linezolid, leave clinicians with...
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Identification of promoter elements in the Dolichospermum circinale AWQC131C saxitoxin gene cluster and the experimental analysis of their use for heterologous expression
BackgroundDolichospermum circinale is a filamentous bloom-forming cyanobacterium responsible for biosynthesis of the paralytic shellfish toxins...
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Role of Bacteriophages in the Evolution of Pathogenic Vibrios and Lessons for Phage Therapy
Viruses of bacteria, i.e., bacteriophages (or phages for short), were discovered over a century ago and have played a major role as a model system...