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Gastrointestinal redox homeostasis in ageing
The gastrointestinal (GI) barrier acts as the primary interface between humans and the external environment. It constantly faces the risk of...
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Ethylene Synthesis and Redox Homeostasis in Plants: Recent Advancement
The life cycle of plants is regulated by ethylene in numerous ways, including adaptations to biotic and abiotic stimuli, flower growth, fruit... -
Nitric Oxide and Cellular Redox Homeostasis in Plants
Attributing to the diverse abiotic stresses and climate fluctuations, the agriculture sector is experiencing some serious misfortunes. This largely... -
MTHFD1 regulates the NADPH redox homeostasis in MYCN-amplified neuroblastoma
MYCN amplification is an independent poor prognostic factor in patients with high-risk neuroblastoma (NB). Further exploring the molecular regulatory...
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Chromatin balances cell redox and energy homeostasis
Chromatin plays a central role in the conversion of energy in cells: alteration of chromatin structure to make DNA accessible consumes energy, and...
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Phytosulfokine contributes to suspension culture of Cunninghamia lanceolata through its impact on redox homeostasis
BackgroundSuspension culture is widely used in the establishment of efficient plant regeneration systems, as well as in the mass production of plant...
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Disturbances in mitochondrial bioenergetics and control quality and unbalanced redox homeostasis in the liver of a mouse model of mucopolysaccharidosis type II
Mucopolysaccharidosis type II (MPS II; Hunter syndrome) is a lysosomal storage disease caused by mutations in the gene encoding the enzyme iduronate...
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NRF2 is essential for iron-overload stimulated osteoclast differentiation through regulation of redox and iron homeostasis
Iron overload enhances osteoclastic bone resorption and induces osteoporosis. Excess iron is highly toxic. The modulation of redox and iron...
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Redox homeostasis of cereals during acclimation to drought
Abiotic stresses are responsible for nearly 90% of all yield losses, around 40% of which are due to drought. Most cereal crops, the mainstay of...
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Herbal and chemical seed potentiations improve the redox health of aged seeds of indigenous aromatic rice cultivars through regulation of oxidative window, gene expression, and restoration of hormonal homeostasis
Previous studies associated with seed potentiation support the critical role of metabolic readjustment in restricting the loss of seed vigor and...
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Everolimus alleviates CD4+ T cell inflammation by regulating autophagy and cellular redox homeostasis
Aging is associated with the onset and progression of multiple diseases, which limit health span. Chronic low-grade inflammation in the absence of...
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Animal models of male subfertility targeted on LanCL1-regulated spermatogenic redox homeostasis
Oxidative stress in spermatozoa is a major contributor to male subfertility, which makes it an informed choice to generate animal models of male...
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Redox homeostasis at SAM: a new role of HINT protein
Main conclusionScHINT1 was identified at sugarcane SAM using subtractive libraries. Here, by bioinformatic tools, two-hybrid approach, and...
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Evaluating the Impact of an Organic Trace Mineral mix on the Redox Homeostasis, Immunity, and Performance of Sows and their Offspring
The objective of the study was to evaluate the effects of trace mineral supplementation in sows during gestation and lactation on the performance and...
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Selenium deficiency-induced multiple tissue damage with dysregulation of immune and redox homeostasis in broiler chicks under heat stress
Broiler chicks are fast-growing and susceptible to dietary selenium (Se) deficiency. This study sought to reveal the underlying mechanisms of how Se...
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Fundamentals of redox regulation in biology
Oxidation–reduction (redox) reactions are central to the existence of life. Reactive species of oxygen, nitrogen and sulfur mediate redox control of...
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Long-term sulforaphane-treatment restores redox homeostasis and prevents cognitive decline in middleaged female and male rats, but cannot revert previous damage in old animals
Aging is a complex and detrimental process, which disrupts most organs and systems within the organisms. The nervous system is morphologically and...
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Methylmalonic acid induces inflammatory response and redox homeostasis disruption in C6 astroglial cells: potential glioprotective roles of melatonin and resveratrol
Methylmalonic acidemia is a neurometabolic disorder biochemically characterized by the accumulation of methylmalonic acid (MMA) in different tissues,...
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Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance
Metastatic breast cancer cells disseminate to organs with a soft microenvironment. Whether and how the mechanical properties of the local tissue...
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Phylogenetic conservation of the interdependent homeostatic relationship of sleep regulation and redox metabolism
Sleep is an essential and evolutionarily conserved process that affects many biological functions that are also strongly regulated by cellular...