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Evaluating the Impact of an Organic Trace Mineral mix on the Redox Homeostasis, Immunity, and Performance of Sows and their Offspring

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Abstract

The objective of the study was to evaluate the effects of trace mineral supplementation in sows during gestation and lactation on the performance and health status of sows and their offspring. Sows (n = 30; Landrace × Yorkshire; avg parity = 3.9) were randomly allocated into two dietary treatments. Sows received a basal diet supplemented with 12 mg/kg Cu, 30 mg/kg Fe, 90 mg/kg Zn, 70 mg/kg Mn, 0.30 mg/kg Se, and 1.5 mg/kg I from an inorganic trace mineral source (ITM) or a blend of hydroxychloride and organic trace mineral source (HOTM) from day 1 of gestation until the end of the lactation period at day 21. Compared to the ITM, the HOTM supplementation increased (P < 0.05) both litter birth weight and individual piglet birth weight. Although not statistically significant, HOTM tended to increase (P = 0.069) the level of lactose in colostrum. HOTM increased (P < 0.05) the concentration of Mn and Se in the colostrum, milk, and serum of sows and/or piglets. Notably, the Zn concentration in the serum of sows was higher in sows supplemented with ITM compared to HOTM. Moreover, HOTM increased (P < 0.05) the activities of GPX and SOD in gestating sows and piglets, as well as increased (P < 0.05) cytokines (IL-1β, TNF-α, and IL-10) in the serum of sows. The immunoglobulins (IgA, IgG, and IgM) also increased in sows and/or piglets at certain experimental time points. In conclusion, HOTM supplementation positively affected piglet development and improved the health status of sows and piglets potentially by regulating redox homeostasis and immunity.

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Data Availability

The datasets used and/or analyzed during the current study are publicly available.

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Funding

This research was supported in part by the Key R&D Program of Shandong Province, China (2023TZXD038), the Fundamental Research Funds for the Central Universities (Project 2662023DKPY002), and a research gift from Trouw Nutrition.

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Author notes

  1. Shao-Qing Wang, Zhe Peng, and Hua Sun contributed equally to the work.

Authors and Affiliations

  1. State Key Laboratory of Agricultural Microbiology, Hubei Hongshan Laboratory, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, 430070, Hubei, China

    Shao-Qing Wang, Zhe Peng, Hua Sun, Lv-hui Sun & Zhang-Chao Deng

  2. Inner Mongolia Academy of Agriculture and Animal Husbandry Science, Hohhot, 010031, Inner Mongolia, China

    Hua Sun

  3. Selko Feed Additives, Nutreco, Amersfoort, The Netherlands

    Yan-Ming Han, Bo Zhang, Lane Pineda & Gavin Boerboom

  4. Tian** Animal Disease Prevention and Control Center, Tian**, 300402, China

    Ying Liu

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Contributions

Shao-Qing Wang, Hua Sun, and Zhe Peng: animal trials, investigation, methodology, and data analysis; Yan-Ming Han, Bo Zhang, Lane Pineda, Gavin Boerboom, and Ying Liu: writing—review and editing, funding acquisition; Lv-Hui Sun, Zhang-Chao Deng, and Ying Liu: supervision, writing—original draft, visualization, writing—review and editing, and project administration. All authors have read and agreed to the published version of the final manuscript.

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Correspondence to Lv-hui Sun, Ying Liu or Zhang-Chao Deng.

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Wang, SQ., Peng, Z., Sun, H. et al. Evaluating the Impact of an Organic Trace Mineral mix on the Redox Homeostasis, Immunity, and Performance of Sows and their Offspring. Biol Trace Elem Res (2024). https://doi.org/10.1007/s12011-024-04300-7

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