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Development of the hyolaryngeal architecture in horseshoe bats: insights into the evolution of the pulse generation for laryngeal echolocation
BackgroundThe hyolaryngeal apparatus generates biosonar pulses in the laryngeally echolocating bats. The cartilage and muscles comprising the...
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Evaluation of anatomical and histological characteristics of human peripheral nerves: as an effort to develop an efficient allogeneic nerve graft
Management of peripheral nerve defects is a complicated problem in clinical contexts. Autologous nerve grafting, a gold standard for surgical...
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The vocal apparatus: An understudied tool to reconstruct the evolutionary history of echolocation in bats?
Laryngeal echolocation in bats could have evolved following two scenarios: a single origin from a common ancestor or an independent acquisition...
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Swallowing-related muscle inflammation and fibrosis induced by a single dose of radiation exposure in mice
BackgroundAlthough radiotherapy is commonly used to treat head and neck cancer, it may lead to radiation-associated dysphagia (RAD). There are...
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Mechanisms of larynx and vocal fold development and pathogenesis
The larynx and vocal folds sit at the crossroad between digestive and respiratory tracts and fulfill multiple functions related to breathing,...
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Innate differences in the molecular signature of normal inferior & superior human parathyroid glands: potential implications for parathyroid adenoma
Primary hyperparathyroidism is a common endocrine disorder. Interestingly, the majority (75%) of parathyroid tumors are localized to the inferior...
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Olfactory-ensheathing cells promote physiological repair of injured recurrent laryngeal nerves and functional recovery of glottises in dogs
The aim of this study was to investigate whether the transplantation of olfactory-ensheathing cells (OECs) could physiologically repair severely...
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Piezo1-expressing vocal fold epithelia modulate remodeling via effects on self-renewal and cytokeratin differentiation
Mechanoreceptors are implicated as functional afferents within mucosa of the airways and the recent discovery of mechanosensitive channels Piezo1 and Piezo2...
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Respiration
Birds have high metabolic rates and so require an efficient means of delivering oxygen to their cells and eliminating carbon dioxide, and the avian...
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An Overview of Mesenchymal Stem Cell-based Therapy Mediated by Noncoding RNAs in the Treatment of Neurodegenerative Diseases
Mesenchymal stem cells (MSCs) have become a promising tool for neurorestorative therapy of neurodegenerative diseases (NDDs), which are mainly...
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RNA sequencing identifies transcriptional changes in the rabbit larynx in response to low humidity challenge
BackgroundVoice disorders are a worldwide problem impacting human health, particularly for occupational voice users. Avoidance of surface dehydration...
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Effect of oesophagectomy on lipid profiles in patients with oesophageal cancer combined with hyperlipidaemia: a retrospective study
BackgroundSurgery is widely regarded as a pivotal therapeutic approach for treating oesophageal cancer, and clinical observations have revealed that...
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Introduction to Rare Genetic Disorders
Rare genetic disorders are a group of diseases that are caused by changes in a person’s genes. These changes can be inherited from parents or occur...
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Roles and action mechanisms of WNT4 in cell differentiation and human diseases: a review
WNT family member 4 (WNT4), which belongs to the conserved WNT protein family, plays an important role in the development and differentiation of many...
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Regenerative medicine approaches for the management of respiratory tract fistulas
Respiratory tract fistulas (or fistulae) are abnormal communications between the respiratory system and the digestive tract or the adjacent organs....
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Clinical manifestations and immune response to tuberculosis
Tuberculosis is a far-reaching, high-impact disease. It is among the top ten causes of death worldwide caused by a single infectious agent; 1.6...
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Therapeutic approach of adipose-derived mesenchymal stem cells in refractory peptic ulcer
Peptic ulcer is one of the most common gastrointestinal tract disorders worldwide, associated with challenges such as refractory morbidity, bleeding,...
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Insights into the Therapeutic Potential of Heparinized Collagen Scaffolds Loading Human Umbilical Cord Mesenchymal Stem Cells and Nerve Growth Factor for the Repair of Recurrent Laryngeal Nerve Injury
Recurrent laryngeal nerve (RLN) injury can result in unilateral or bilateral vocal cords paralysis, thereby causing a series of complications, such...
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Identification of ferroptosis genes in immune infiltration and prognosis in thyroid papillary carcinoma using network analysis
BackgroundPapillary thyroid carcinoma (PTC) is the most common thyroid cancer. While many patients survive, a portion of PTC cases display high...
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Head and Neck Squamous Cell Carcinoma: Risk Factors, Molecular Alterations, Immunology and Peptide Vaccines
Head and neck squamous cell carcinoma (HNSCC) arises from the epithelial lining of the oral cavity, hypopharynx, oropharynx, and larynx. There are...
