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Protein–Protein Interaction: Bacterial Two Hybrid
The bacterial two-hybridBacterial two-hybrid (BACTH, for “Bacterial Adenylate Cyclase-based Two-Hybrid”) system is a simple and fast genetic approach...
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Protein–Protein Interaction: Tandem Affinity Purification in Bacteria
The discovery of protein–protein interaction networks can lead to the unveiling of protein complex(es) forming cellular machinerie(s) or reveal...
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Protein–Protein Interaction Network Analysis Using NetworkX
In recent years, extracting information from biological data has become a particularly valuable way of gaining knowledge. Molecular interaction...
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Protein-Protein Interaction Studies Using Molecular Dynamics Simulation
Protein-protein interactionProtein-protein interaction (PPI) is a crucial event for many biological functions. Studying the molecular details of PPI...
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Protein–Protein Interactions: Co-immunoprecipitation
Proteins often do not function as single substances but rather as team players in a dynamic network. Growing evidences show that protein–protein...
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Building Protein–Protein Interaction Graph Database Using Neo4j
A cell’s various components interact with each other in a coordinated manner to respond to environmental cues and intracellular signals. Compared to...
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Protein-Protein Binding Kinetics by Biolayer Interferometry
The specific kinetics and thermodynamics of protein-protein interactions underlie the molecular mechanisms of cellular functions; hence the...
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Cytotrap: An Innovative Approach for Protein–Protein Interaction Studies for Cytoplasmic Proteins
Protein–protein interaction map** has gained immense importance in understanding protein functions in diverse biological pathways. There are...
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Protein–Protein Interaction Network Exploration Using Cytoscape
As the protein–protein interaction (PPI) data increase exponentially, the development and usage of computational methods to analyze these datasets...
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Assessing Peroxisomal Protein Interaction by Immunoprecipitation
Organelles physically interact with each other via protein tethering complexes that bridge the opposing membranes. Organelle membrane contacts are...
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Predicting Protein Interaction Sites Using PITHIA
Several proteins work independently, but the majority work together to maintain the functions of the cell. Thus, it is crucial to know the...
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Using PlaPPISite to Predict and Analyze Plant Protein–Protein Interaction Sites
Proteome-wide characterization of protein–protein interactions (PPIs) is crucial to understand the functional roles of protein machinery within cells...
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Protein–Protein Interactions: Oxidative Bacterial Two Hybrid
Protein–protein interaction studies are essential to understand how proteins organize themselves into interaction networks and thus influence...
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Protein features fusion using attributed network embedding for predicting protein-protein interaction
BackgroundProtein-protein interactions (PPIs) hold significant importance in biology, with precise PPI prediction as a pivotal factor in...
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xCAPT5: protein–protein interaction prediction using deep and wide multi-kernel pooling convolutional neural networks with protein language model
BackgroundPredicting protein–protein interactions (PPIs) from sequence data is a key challenge in computational biology. While various computational...
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Machine Learning Methods for Virus–Host Protein–Protein Interaction Prediction
The attachment of a virion to a respective cellular receptor on the host organism occurring through the virus–host protein–protein interactions...
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Centrality Analysis of Protein–Protein Interaction Networks Using R
Proteins are structural and functional components of cells. They interact with each other to drive specific cellular functions. The physical and...
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Using protein language models for protein interaction hot spot prediction with limited data
BackgroundProtein language models, inspired by the success of large language models in deciphering human language, have emerged as powerful tools for...
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Protein–Protein Interactions: Yeast Two Hybrid
The yeast two-hybridYeast two-hybrid (Y2H) systemTwo-hybrid system is a powerful and commonly used genetic tool to investigate the interaction...
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Protein–Protein Interactions in Cancer
Cancerous state is often associated with the aberrant expression of several critical proteins, which in turn, modulate interactions with other...