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  1. Autosis: a new form of cell death in myocardial ischemia–reperfusion injury

    Cardiomyocytes undergo a variety of cell death events during myocardial ischemia‒reperfusion injury (MIRI). Understanding the causes of cardiomyocyte...

    **aoting Yang, Hui Wu, ... Yi Li in Molecular and Cellular Biochemistry
    Article 09 April 2024
  2. PIM3 regulates myocardial ischemia/reperfusion injury via ferroptosis

    Background

    Myocardial ischemia/reperfusion (I/R) injury is closely related with cardiovascular diseases; however, the underlying pathogenic mechanisms...

    Ting Li, Fangyao Liu, ... Yushan Yang in Genes & Genomics
    Article 26 December 2023
  3. PCSK9 regulates myocardial ischemia–reperfusion injury through parkin/pink1-mediated autophagy pathway

    Objectives

    This study aimed at investigating the role of the proprotein convertase subtilisin/Kexin type 9 (PCSK9)-mediated autophagy on myocardial...

    Guangwei Huang, Hailong Bao, ... Wei Li in Molecular & Cellular Toxicology
    Article 24 March 2023
  4. MicroRNA-specific therapeutic targets and biomarkers of apoptosis following myocardial ischemia–reperfusion injury

    MicroRNAs are single-stranded non-coding RNAs that participate in post-transcriptional regulation of gene expression, it is involved in the...

    Teng Ge, Bo Ning, ... Mingjun Zhao in Molecular and Cellular Biochemistry
    Article 25 October 2023
  5. Targeting the Ferroptosis and Endoplasmic Reticulum Stress Signaling Pathways by CBX7 in Myocardial Ischemia/reperfusion Injury

    Ferroptosis and endoplasmic reticulum stress (ERS) are common events in the process of myocardial ischemia/reperfusion injury (IRI). The suppression...

    Weipeng Jiang, Zeyu Yan, ... Baihua Zhou in Cell Biochemistry and Biophysics
    Article 29 May 2024
  6. The interplay between T lymphocytes and macrophages in myocardial ischemia/reperfusion injury

    Acute myocardial infarction is one of the most important causes of death in the world, causing a huge health and economic burden to the world. It is...

    Article 04 August 2023
  7. AMPK, a key molecule regulating aging-related myocardial ischemia-reperfusion injury

    Aging leads to the threat of more diseases to the biological anatomical structure and the decline of disease resistance, increasing the incidence and...

    **aorui Yin, Ziyuan Guo, Chunli Song in Molecular Biology Reports
    Article 01 February 2024
  8. Ubiquitin-specific protease 7 regulates myocardial ischemia/reperfusion injury by stabilizing Keap1

    Myocardial ischemia/reperfusion (I/R) injury is a complex pathological process that is still not fully understood. The oxidative stress response has...

    Qiong Xu, Mingke Liu, ... Ningning Liu in Cell Death Discovery
    Article Open access 16 June 2022
  9. NEDD4 ameliorates myocardial reperfusion injury by preventing macrophages pyroptosis

    Objectives

    The inflammatory cascade and cell death post-myocardial ischemia reperfusion (MI/R) are very complex. Despite the understanding that...

    Wen**g Sun, Hongquan Lu, ... Shujuan Dong in Cell Communication and Signaling
    Article Open access 02 February 2023
  10. Inhibition of circ_0073932 attenuates myocardial ischemia‒reperfusion injury via miR-493-3p/FAF1/JNK

    Oxidative stress and apoptosis play crucial roles in myocardial ischemia‒reperfusion injury (MIRI). In this study, we investigated the role of...

    Yang Su, Lili Zhao, ... **aoming Yang in In Vitro Cellular & Developmental Biology - Animal
    Article 05 April 2024
  11. Modified APJ Receptor Peptide Ligands as Postconditioning Drugs in Myocardial Ischaemia/Reperfusion Injury

    The apelin/APJ system is involved in many physiological functions and pathophysiological effects in cardiovascular diseases, making it a promising...

    Oleg I. Pisarenko, Irina M. Studneva in International Journal of Peptide Research and Therapeutics
    Article 14 February 2023
  12. Histone modification landscape and the key significance of H3K27me3 in myocardial ischaemia/reperfusion injury

    Histone modifications play crucial roles in the pathogenesis of myocardial ischaemia/reperfusion (I/R) injury. However, a genome-wide map of histone...

    Le Ni, Bowen Lin, ... Yi-Han Chen in Science China Life Sciences
    Article 13 February 2023
  13. Gypenoside A Protects Human Myocardial Cells from Ischemia/Reperfusion Injury via the circ_0010729/miR-370-3p/RUNX1 Axis

    Abstract

    Ischemia/reperfusion (I/R) injury is one of the major causes of cardiovascular disease. Gypenoside A (GP), the main active component of Gynost...

    Hailiang Ma, Yuanben Lu, ... Li Wang in Biochemistry (Moscow)
    Article 31 May 2024
  14. The m6A methylation enzyme METTL14 regulates myocardial ischemia/reperfusion injury through the Akt/mTOR signaling pathway

    Herein, we investigated the role of the m 6 A methylation enzyme METTL14 in regulating myocardial ischemia/reperfusion injury (IR/I) through the...

    Chunchun Wu, Youfang Chen, ... Shengnan Wang in Molecular and Cellular Biochemistry
    Article 12 July 2023
  15. Myocardial Electrophysiological Response to Ischemia and Reperfusion Depends on the Age of Rats

    Abstract

    Age is a major driver of the risk of acute myocardial infarction and malignant ventricular arrhythmias. However, age-related changes in the...

    E. V. Minnebaeva, A. V. Durkina, ... O. G. Bernikova in Journal of Evolutionary Biochemistry and Physiology
    Article 01 December 2022
  16. STUB1 is acetylated by KAT5 and alleviates myocardial ischemia-reperfusion injury through LATS2-YAP-β-catenin axis

    Myocardial ischemia-reperfusion injury (MIRI) is involved in the pathogenesis of multiple cardiovascular diseases. This study elucidated the...

    Can Liu, Zhongxuan Gui, ... Shenglin Ge in Communications Biology
    Article Open access 01 April 2024
  17. PPARγ Regulates Macrophage Polarization by Inhibiting the JAK/STAT Pathway and Attenuates Myocardial Ischemia/Reperfusion Injury In Vivo

    This study aimed to investigate the role of PPARγ and underlying mechanisms in myocardial ischemia/reperfusion injury (IRI). IRI was surgically...

    Shengnan Wang, Yinlian Cai, ... Chunchun Wu in Cell Biochemistry and Biophysics
    Article 02 May 2023
  18. MiR-130a-3p regulates FUNDC1-mediated mitophagy by targeting GJA1 in myocardial ischemia/reperfusion injury

    Understanding the complex pathogenesis in myocardial ischemia/reperfusion (I/R) injury (IRI) is an urgent problem in clinical trials. Increasing...

    Yan Yan, Liu-yang Tian, ... **ao-**g Zhao in Cell Death Discovery
    Article Open access 25 February 2023
  19. Decreased MFN2 activates the cGAS-STING pathway in diabetic myocardial ischaemia–reperfusion by triggering the release of mitochondrial DNA

    Background

    The cause of aggravation of diabetic myocardial damage is yet to be elucidated; damage to mitochondrial function has been a longstanding...

    Yonghong **ong, Yan Leng, ... Zhongyuan **a in Cell Communication and Signaling
    Article Open access 03 August 2023
  20. The E3 ubiquitin ligase MARCH2 protects against myocardial ischemia-reperfusion injury through inhibiting pyroptosis via negative regulation of PGAM5/MAVS/NLRP3 axis

    Inflammasome activation and pyroptotic cell death are known to contribute to the pathogenesis of cardiovascular diseases, such as myocardial...

    Shuolin Liu, Yaguang Bi, ... Yingmei Zhang in Cell Discovery
    Article Open access 27 February 2024
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