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Gap Junctions in Ctenophora
Gap junction proteins form specialized intercellular communication channels, including electrical synapses, that regulate cellular metabolism and... -
DNA Methylation in Ctenophores
Epigenomic regulation and dynamic DNA methylation, in particular, are widespread mechanisms orchestrating the genome operation across time and... -
A Dye Uptake Assay to Measure Large-Pore Channel Activity in Trypanosoma cruzi
Large-pore channels allow the exchange of ions and molecules between the intra- and extracellular compartments. These channels are structures formed... -
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Brief History of Placozoa
Placozoans are morphologically the simplest free-living animals. They represent a unique window of opportunities to understand both the origin of the... -
Brief History of Ctenophora
Ctenophores are the descendants of the earliest surviving lineage of ancestral metazoans, predating the branch leading to sponges (Ctenophore-first... -
Enhanced Methodologies for Investigating the Electrophysiological Characteristics of Endogenous Pannexin 1 Intercellular Cell–Cell Channels
Gap junctions, pivotal intercellular conduits, serve as communication channels between adjacent cells, playing a critical role in modulating membrane... -
Neuronal gene expression in two generations of the marine parasitic worm, Cryptocotyle lingua
Trematodes, or flukes, undergo intricate anatomical and behavioral transformations during their life cycle, yet the functional changes in their...
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Analysis of Molecular Circuitry Integrated to Lethargus State of Caenorhabditis elegans: A Review
Sleep is a quintessential phenomenon of our nervous system. In spite of enduring research, the complexity of brain makes it more challenging to...
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Analysis of the C. elegans Germline Stem Cell Pool
The Caenorhabditis elegans germline is an excellent model for studying the genetic and molecular regulation of stem cell self-renewal and progression... -
Structure and Functions of Gap Junctions and Their Constituent Connexins in the Mammalian CNS
Abstract —Numerous data obtained in the last 20 years indicate that all parts of the mature central nervous system, from the retina and olfactory bulb...
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Are there gap junctions without connexins or pannexins?
BackgroundGap junctions (GJ) are one of the most common forms of intercellular communication. GJs are assembled from proteins that form channels...
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Human Pannexin 1 channel: Insight in structure–function mechanism and its potential physiological roles
Pannexins, large non-gap junction super family exists in vertebrates, play multiple roles in different cellular functions through their ATP release....
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Cell-Materials Interaction
Cells are able to respond to different physicochemical stimuli due to a complex molecular system that governs that response. The cell response to... -
Passive Membrane Properties and Spike Characteristics in a Pair of Identified Electrically Coupled Lymnaea stagnalis Neurons under Long-Term Experimental Hyperglycemia
AbstractMicroelectrode technique was used to study the responses of the electrically coupled giant peptidergic VD1 and RPaD2 neurons within the...
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Neurocircuitry of Circadian Clocks
Classical studies using several insect species have demonstrated that the principal circadian clock cells that generate circadian oscillations and... -
Host-pathogen coevolution drives innate immune response to Aphanomyces astaci infection in freshwater crayfish: transcriptomic evidence
BackgroundFor over a century, scientists have studied host-pathogen interactions between the crayfish plague disease agent Aphanomyces astaci and...
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Post-diapause transcriptomic restarts: insight from a high-latitude copepod
BackgroundDiapause is a seasonal dormancy that allows organisms to survive unfavorable conditions and optimizes the timing of reproduction and...
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Analysing bioelectrical phenomena in the Drosophila ovary with genetic tools: tissue-specific expression of sensors for membrane potential and intracellular pH, and RNAi-knockdown of mechanisms involved in ion exchange
BackgroundChanges in transcellular bioelectrical patterns are known to play important roles during developmental and regenerative processes. The Drosophila...