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Single-cell dissection of remodeled inflammatory ecosystem in primary and metastatic gallbladder carcinoma
Gallbladder carcinoma (GBC) is the most common biliary tract malignancy with the lowest survival rate, primarily arising from chronic inflammation....
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Risk factors for cholesterol polyp formation in the gallbladder are closely related to lipid metabolism
BackgroundThe purpose of this study was to assess the risk factors for cholesterol polyp formation in the gallbladder.
MethodsThis was a multicenter...
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Free fatty acids and triglyceride change in the gallbladder bile of gallstone patients with pancreaticobiliary reflux
BackgroundPancreaticobiliary reflux (PBR) causes chronic inflammation of the gallbladder mucosa and changes in the bile components, which are known...
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Association between the non-HDL-cholesterol-to-HDL-cholesterol ratio and the risk of gallbladder polyp formation among men: a retrospective cohort study
BackgroundDyslipidaemia and male sex are associated with gallbladder polyp (GBP) formation. However, the potential relation between the...
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Microorganisms isolated from the bile of the patients who have undergone cholecystectomy and their antibiotic resistance pattern: multicenter prospective study
BackgroundGallbladder and biliary tract infections are diseases with high mortality rates if they are not treated properly. Microbiological...
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Herbs and Herbal Formulations for the Management and Prevention of Gastrointestinal Diseases
Diseases affecting the digestive tract’s activities are referred to as GIT disorders. Stomach or abdominal pain, dyspepsia, bloating, diarrhea,... -
Herbs and Herbal Formulations for the Management and Prevention of Gastrointestinal Diseases
Diseases affecting the digestive tract’s activities are referred to as GIT disorders. Stomach or abdominal pain, dyspepsia, bloating, diarrhea,... -
Cholecystectomy promotes colon carcinogenesis by activating the Wnt signaling pathway by increasing the deoxycholic acid level
PurposeCholecystectomy (XGB) is widely recognized as a risk factor for colon cancer (CC). Continuous exposure of the colonic epithelium to...
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An updated and comprehensive review of traditional uses, phytochemistry, and pharmacological progress on the Hypecoum genus
The Hypecoum genus belongs to the family Papaveraceae, consists of roughly 16 accepted species, and is extensively distributed from the Mediterranean...
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Understanding the mechanisms and translational implications of the microbiome for cancer therapy innovation
The intersection of the microbiota and cancer and the mechanisms that define these interactions are a fascinating, rapidly evolving area of cancer...
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Medicinal plants cultivated in Egypt with anticancer potential; a systematic review
The increase in cases of various cancers, the number of cancer patients, and the serious side effects of current chemical treatments have encouraged...
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Artificial intelligence and guidance of medicine in the bubble
Microbubbles are nanosized gas-filled bubbles. They are used in clinical diagnostics, in medical imaging, as contrast agents in ultrasound imaging,...
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Alterations of the bile microbiome is associated with progression-free survival in pancreatic ductal adenocarcinoma patients
BackgroundPatients with pancreatic ductal adenocarcinoma (PDAC) display an altered oral, gastrointestinal, and intra-pancreatic microbiome compared...
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The microbial landscape of colorectal cancer
Colorectal cancer (CRC) is a substantial source of global morbidity and mortality in dire need of improved prevention and treatment strategies. As...
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Osteopontin: an essential regulatory protein in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic lung disease characterized by abnormal proliferation and activation of fibroblasts,...
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The impact of the gut microbiome on tumor immunotherapy: from mechanism to application strategies
Immunotherapy is one of the fastest develo** areas in the field of oncology. Many immunological treatment strategies for refractory tumors have...
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Cancer trigger or remedy: two faces of the human microbiome
Currently, increasing attention cancer treatment has focused on molecularly targeted therapies and more recently on immunotherapies targeting immune...
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A Systematic Review of the Clinical Use of Curcumin for the Management of Gastrointestinal Diseases
Gastrointestinal (GI) diseases are highly prevalent worldwide, with considerable morbidity and mortality. Curcumin has been used for many years as a... -
Structural based screening of potential inhibitors of SMAD4: a step towards personalized medicine for gall bladder and other associated cancers
Gall bladder cancer (GBC) is an aggressive and most common malignancy of biliary tract lacking effective treatment due to unavailability of suitable...
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March of molecular breeding techniques in the genetic enhancement of herbal medicinal plants: present and future prospects
Herbal medicinal plants constitute valuable resources of natural secondary active biomolecules that supplement human nourishment, support health...