Search
Search Results
-
SEEI: spherical evolution with feedback mechanism for identifying epistatic interactions
BackgroundDetecting epistatic interactions (EIs) involves the exploration of associations among single nucleotide polymorphisms (SNPs) and complex...
-
A Novel Detection Method for High-Order SNP Epistatic Interactions Based on Explicit-Encoding-Based Multitasking Harmony Search
To elucidate the genetic basis of complex diseases, it is crucial to discover the single-nucleotide polymorphisms (SNPs) contributing to disease...
-
Next-Gen GWAS: full 2D epistatic interaction maps retrieve part of missing heritability and improve phenotypic prediction
The problem of missing heritability requires the consideration of genetic interactions among different loci, called epistasis. Current GWAS...
-
GWAS for main effects and epistatic interactions for grain morphology traits in wheat
In the present study in wheat, GWAS was conducted for identification of marker trait associations (MTAs) for the following six grain morphology...
-
ABCAE: Artificial Bee Colony Algorithm with Adaptive Exploitation for Epistatic Interaction Detection
The detection of epistatic interactions among multiple single-nucleotide polymorphisms (SNPs) in complex diseases has posed a significant challenge...
-
Identification of a major QTL and genome-wide epistatic interactions for single vs. paired spikelets in a maize-teosinte F2 population
Maize ear carries paired spikelets, whereas the ear of its wild ancestor, teosinte, bears single spikelets. However, little is known about the...
-
Quantitative-enhancer-FACS-seq (QeFS) reveals epistatic interactions among motifs within transcriptional enhancers in develo** Drosophila tissue
Understanding the contributions of transcription factor DNA binding sites to transcriptional enhancers is a significant challenge. We developed...
-
Large sample size and nonlinear sparse models outline epistatic effects in inflammatory bowel disease
BackgroundDespite clear evidence of nonlinear interactions in the molecular architecture of polygenic diseases, linear models have so far appeared...
-
Genetic dissection of additive and epistatic quantitative trait loci controlling pod number per plant in peanut (Arachis hypogaea L.)
Pod number per plant (PN) is an important yield component trait in peanut. This study used a recombinant inbred line (RIL) population consisting of...
-
GEP-EpiSeeker: a gene expression programming-based method for epistatic interaction detection in genome-wide association studies
BackgroundIdentification of epistatic interactions provides a systematic way for exploring associations among different single nucleotide...
-
Identification and characterization of pleiotropic and epistatic QDRL conferring partial resistance to Pythium irregulare and P. sylvaticum in soybean
Key messagePleiotropic and epistatic quantitative disease resistance loci (QDRL) were identified for soybean partial resistance to different isolates...
-
Identification of main and epistatic QTLs and QTL through environment interactions for eating and cooking quality in Iranian rice
Breeding new rice varieties with high Eating and Cooking Quality (ECQ) characteristics is an important goal in rice breeding programs. To this end,...
-
Map** of additive and epistatic QTLs linked to seed longevity in bread wheat (Triticum aestivum L.)
Plant genetic resources are stored and regenerated in > 1750 gene banks storing > 7,000,000 accessions. Since seeds are the primary storage units,...
-
Main effect and epistatic QTL affecting spike shattering and association with plant height revealed in two spring wheat (Triticum aestivum L.) populations
Key messageA major QTL on chromosome arm 4BS was associated with reduced spike shattering and reduced plant height in coupling phase, and a second...
-
Revealing third-order interactions through the integration of machine learning and entropy methods in genomic studies
BackgroundNon-linear relationships at the genotype level are essential in understanding the genetic interactions of complex disease traits....
-
Map** of main and hidden epistatic QTL effects in spring wheat population using medium parental FHB resistance
Fusarium head blight (FHB) is a devastating disease lowering the yield and quality of wheat. Intensive use of limited allelic pools critically...
-
Epistatic interaction effect between chromosome 1BL (Yr29) and a novel locus on 2AL facilitating resistance to stripe rust in Chinese wheat Changwu 357-9
Key messageFour stable QTL for adult plant resistance were identified in wheat line Changwu 357-9, including a new QTL on 2AL showing significant...
-
Epistatic interaction between Rhg1-a and Rhg2 in PI 90763 confers resistance to virulent soybean cyst nematode populations
Key messageAn epistatic interaction between SCN resistance loci rhg1-a and rhg2 in PI 90763 imparts resistance against virulent SCN populations...
-
Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control
p38 mitogen-activated protein kinases (MAPKs) participate in autophagic signaling; and previous reports suggest that pyridinyl imidazole p38 MAPK...
-
Identification of major consensus and epistatic QTLs for late leaf spot resistance in a cultivated groundnut breeding line VG 9514
A late leaf spot resistant breeding line VG 9514 was bred through interspecific hybridization between Arachis hypogaea L. and Arachis cardenasii ....
