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Advancing Use of DEXA Scans to Quantitatively and Qualitatively Evaluate Lateral Spinal Curves, for Preliminary Identification of Adolescent Idiopathic Scoliosis
Dual-energy X-ray absorptiometry (DEXA) scan is an emerging screening method for identifying likely adolescent idiopathic scoliosis (AIS). Using DEXA...
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Evaluation of Bone Turnover Markers Such as Osteoprotegerin, Sclerostin and Dickkopf-1 in Subclinical Hyperthyroidism
In this study, it was aimed to assess effects of subclinical hyperthyroidism (SH) on bone metabolism using osteoprotegerin (OPG), sclerostin,...
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Spondyloocular Syndrome: First Case of Rare Osseous and Ocular Syndrome from India with Novel Mutation and Expanded Phenotypic Spectrum
Spondyloocular syndrome (SOS) is a rare autosomal recessive skeletal and ocular disorder with variable phenotypes. It is caused by pathogenic...
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Detrimental Association Between Blood Cadmium Concentration and Trabecular Bone Score
Osteoporosis has been recognized as a significant cause of disability in the elderly leading to heavy socioeconomic burden. Current measurements such...
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Salivary amylase gene (AMY1) copy number variation has only a minor correlation with body composition in Chinese adults
BackgroundAccording to the WHO, about 39% of the global adult population were overweight or obese in 2016. Obesity has high heritability, with more...
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Dual-energy X-ray absorptiometry scans accurately predict differing body fat content in live sheep
BackgroundThere is considerable interest in implementing mobile scanning technology for on-farm body composition analysis on live animals. These...
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Evaluating osteoporosis and bone quality in the aging spine: modern considerations for surgical management in the geriatric population
Surgical management paradigms of spinal pathologies in the aging population carry inherent substantial risks, with surgical complications being more...
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TBC1D1 is an energy-responsive polarization regulator of macrophages via governing ROS production in obesity
Energy status is linked to the production of reactive oxygen species (ROS) in macrophages, which is elevated in obesity. However, it is unclear how...
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Selective targeting of angiopoietin-like 3 (ANGPTL3) with vupanorsen for the treatment of patients with familial partial lipodystrophy (FPLD): results of a proof-of-concept study
BackgroundFamilial partial lipodystrophy (FPLD) is a rare disease characterized by selective loss of peripheral subcutaneous fat, associated with...
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7-MEGA™ inhibits adipogenesis in 3T3-L1 adipocytes and suppresses obesity in high-fat-diet-induced obese C57BL/6 mice
BackgroundOverweight, often known as obesity, is the abnormal and excessive accumulation of fat that exposes the health of a person at risk by...
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The verification of the reliability of a triglyceride–glucose index and its availability as an advanced tool
BackgroundThe triglyceride–glucose (TyG) index has been considered as insulin resistance (IR) assessment index. The current study aimed to verify the...
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Body fat and circulating leptin levels in the captive short-beaked echidna (Tachyglossus aculeatus)
It is possible that the reproductive strategy of the short-beaked echidna is related to seasonal changes in fat deposition and energy availability,...
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Characterizing phenotypic data of Peromyscus leucopus compared to C57BL/6J Mus musculus and diversity outbred (DO) Mus musculus
Translational research is commonly performed in the C57B6/J mouse strain, chosen for its genetic homogeneity and phenotypic uniformity. Here, we...
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The microarchitecture and chemical composition of the femur neck of senescent female rats after different physical training protocols
A sedentary lifestyle, coupled with a decrease in estrogen, impairs bone homeostasis, favoring to the development of osteopenia and osteoporosis,...
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Bone Mediated and Moderated the Associations Between Sarcopenic Obesity Indices and Cardiovascular Disease Risk Scores
To evaluate mediation and moderation of bone on the association of sarcopenic obesity (SO) indices using the metabolic load-capacity model with the...
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Grip strength performance from 9431 participants of the GenoFit study: normative data and associated factors
Weak grip strength is a strong predictor of multiple adverse health outcomes and an integral diagnostic component of sarcopenia. However, the limited...
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Sex-Related Neuromuscular Adaptations to Youth Obesity: Force, Muscle Mass, and Neural Issues
Young obese are generally stronger than their typically develo** counterparts. Strength differences could be partly ascribed to nervous...
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Asprosin is a Reliable Predictor of Osteoporosis in Type 2 Diabetic Postmenopausal Women: A Case–Control Study
The study evaluates Asprosin's value in diabetic postmenopausal women, examining its reliability as a predictor for osteoporosis (OP) in the second...
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Blockage of PPARγ T166 phosphorylation enhances the inducibility of beige adipocytes and improves metabolic dysfunctions
Beige adipocytes in mammalian white adipose tissue (WAT) can reinforce fat catabolism and energy expenditure. Promoting beige adipocyte biogenesis is...
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Combined aerobic and strength exercise training on biological ageing in Singaporean breast cancer patients: protocol for the Breast Cancer Exercise Intervention (BREXINT) Pilot Study
Breast cancer (BC) is the most prominent cancer amongst women, but fortunately, early diagnosis and advances in multimodality treatments have...
