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The role and intervention of mitochondrial metabolism in osteoarthritis
Osteoarthritis (OA), a prevalent degenerative joint disease, affects a substantial global population. Despite the elusive etiology of OA, recent...
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ER Membrane Lipid Composition and Metabolism: Lipidomic Analysis
Plant ER membranes are the major site of biosynthesis of several lipid families (phospholipids, sphingolipids, neutral lipids such as sterols and...
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Lipid Metabolism, Compartmentalization and Signalling in the Regulation of Pollen Tube Growth
To understand the biological context of lipid metabolism and signalling in pollen, we have to consider male gametophytes as organisms optimised...
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Dry immersion rapidly disturbs iron metabolism in men and women: results from the VIVALDI studies
Iron is essential for cell respiration, muscle metabolism, and oxygen transport. Recent research has shown that simulated microgravity rapidly...
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Unraveling the impacts of nano-scale carbon exposure on nitrogen metabolism during early seedling establishment in Zea mays L. roots
Background and aimsElucidating the relationship between extraneous nano-scale carbon properties and the metabolomic response of early Zea mays L ....
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LINC317.5 as a novel biomarker for hypertriglyceridemia in abnormal glucose metabolism
The global rise in prediabetes and diabetes, with type 2 diabetes (T2DM) being predominant, highlights the association between T2DM and...
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Reprogramming of lipid metabolism in the tumor microenvironment: a strategy for tumor immunotherapy
Lipid metabolism in cancer cells has garnered increasing attention in recent decades. Cancer cells thrive in hypoxic conditions, nutrient deficiency,...
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Give and Take: The Reciprocal Control of Metabolism and Cell Cycle
Cell cycle is an ordered sequence of events that occur in a cell preparing for cell...
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Cepharanthine, a regulator of keap1-Nrf2, inhibits gastric cancer growth through oxidative stress and energy metabolism pathway
Cepharanthine (CEP), a bioactive compound derived from Stephania Cephalantha Hayata , is cytotoxic to various malignancies. However, the underlying...
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Amino acid metabolism dysregulation associated with inflammation and insulin resistance in HIV-infected individuals with metabolic disorders
Amino acid metabolic profile, particularly its association with clinical characteristics, remains unclear in patients with human immunodeficiency...
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Appropriate dietary phenylalanine improved growth, protein metabolism and lipid metabolism, and glycolysis in largemouth bass (Micropterus salmoides)
The purpose of this study was aimed to determine the appropriate level of dietary phenylalanine and explored the influences of phenylalanine on...
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Sulfate transport and metabolism: strategies to improve the seed protein quality
Sulfur-containing amino acids (SAA), namely methionine, and cysteine are crucial essential amino acids (EAA) considering the dietary requirements of...
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Opposite effects of low-carbohydrate high-fat diet on metabolism in humans and mice
BackgroundLow-carbohydrate diet (LCD) is effective for weight loss and glycaemic control in humans. Here, the study aimed to explore the effects of...
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Tryptophan metabolism in digestive system tumors: unraveling the pathways and implications
Tryptophan (Trp) metabolism plays a crucial role in influencing the development of digestive system tumors. Dysregulation of Trp and its metabolites...
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Lipid Metabolism and Homeostasis in Ferroptosis
Lipids are a diverse group of molecules that are crucial for cell structure, energy storage, and cell signaling. Maintaining lipid homeostasis...
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Breast cancer therapy: from the perspective of glucose metabolism and glycosylation
Breast cancer is a leading cause of mortality and the most prevalent form of malignant tumor among women worldwide. Breast cancer cells exhibit an...
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USP43 stabilizes c-Myc to promote glycolysis and metastasis in bladder cancer
A hallmark of tumor cells, including bladder cancer (BLCA) cells, is metabolic reprogramming toward aerobic glycolysis (Warburg effect). The...
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Phospholipid Metabolism in Stem Cells and Its Application to the Pathophysiological Analysis
Phospholipids are classified into glycerophospholipids and sphingolipids, which are lipid bilayer components and act as a source of various bioactive...
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Cross Talk Between Metabolism and the Cell Division Cycle
Cell division requires a massive rewiring of cellular pathways, including molecular routes involved in providing energy for cell survival and...
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Prostate lineage-specific metabolism governs luminal differentiation and response to antiandrogen treatment
Lineage transitions are a central feature of prostate development, tumourigenesis and treatment resistance. While epigenetic changes are well known...
