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Structure of plant photosystem I in a native assembly state defines PsaF as a regulatory checkpoint
Plant photosystem I (PSI) consists of at least 13 nuclear-encoded and 4 chloroplast-encoded subunits that together act as a sunlight-driven...
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Ginsenoside Rg3 enriches SCFA-producing commensal bacteria to confer protection against enteric viral infection via the cGAS-STING-type I IFN axis
The microbiota-associated factors that influence host susceptibility and immunity to enteric viral infections remain poorly defined. We identified...
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Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport
Dynein and kinesin motors mediate long-range intracellular transport, translocating towards microtubule minus and plus ends, respectively. Cargoes...
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Revisiting the anticancer properties of phosphane(9-ribosylpurine-6-thiolato)gold(I) complexes and their 9H-purine precursors
New mono- and di-nuclear thio-purine and thio-purine nucleoside gold(I) complexes were synthesized, characterized, and evaluated in vitro for...
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SRSF1 regulates primordial follicle formation and number determination during meiotic prophase I
BackgroundOvarian folliculogenesis is a tightly regulated process leading to the formation of functional oocytes and involving successive quality...
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Content and tissue expression of Collagen I, Collagen IV, and Laminin in the Extracellular Matrix in Prostate Adenocarcinoma
Prostate cancer is one of the most common neoplasm in the male population. It is not known why some tumors become more aggressive than others....
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“MeiQuant”: An Integrated Tool for Analyzing Meiotic Prophase I Spread Images
Immunocytochemical analysis of meiotic proteins on mouse chromosome spreads is one method of choice to study prophase I chromosome organization and...
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How Can I Get Organised?
Getting started is one of the hardest parts of doing a dissertation, especially if you have no idea where to begin. This chapter is all about getting...
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Drop-casted Photosystem I/cytochrome c multilayer films for biohybrid solar energy conversion
One of the main barriers to making efficient Photosystem I-based biohybrid solar cells is the need for an electrochemical pathway to facilitate...
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Type I methanotrophs dominated methane oxidation and assimilation in rice paddy fields by the consequence of niche differentiation
Conventional aerobic methanotrophs oxidize methane (CH 4 ) and covert CH 4 -derived carbon (C) into biomass at the oxic-anoxic interface of inundated...
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Morphological, Biological, and Molecular Characterization of Type I Granuloviruses of Spodoptera frugiperda
Granuloviruses (GVs) Betabaculovirus associated with the fall armyworm (FAW), Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae), especially...
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CapsNet-MHC predicts peptide-MHC class I binding based on capsule neural networks
The Major Histocompatibility Complex (MHC) binds to the derived peptides from pathogens to present them to killer T cells on the cell surface....
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Algal photosystem I dimer and high-resolution model of PSI-plastocyanin complex
Photosystem I (PSI) enables photo-electron transfer and regulates photosynthesis in the bioenergetic membranes of cyanobacteria and chloroplasts....
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Inositol hexakisphosphate primes syndapin I/PACSIN 1 activation in endocytosis
Endocytosis is controlled by a well-orchestrated molecular machinery, where the individual players as well as their precise interactions are not...
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Relaxed Cleavage Specificity of Hyperactive Variants of Escherichia coli RNase E on RNA I
RNase E is an essential enzyme in Escherichia coli . The cleavage site of this single-stranded specific endoribonuclease is well-characterized in many...
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Effect of CITES Appendix I listing on illegal pangolin trade as gauged from seizure reports in Indonesia
Pangolins, one of the most heavily trafficked animals, have become the poster child for the illegal wildlife trade. Pangolins are protected...
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The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors
Antipsychotic drugs are the mainstay of treatment for schizophrenia and provide adjunct therapies for other prevalent psychiatric conditions,...
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Increased endogenous PKG I activity attenuates EGF-induced proliferation and migration of epithelial ovarian cancer via the MAPK/ERK pathway
The type I cGMP-dependent protein kinase (PKG I) is recognized as a tumor suppressor, but its role in EGFR regulated epithelial ovarian cancer (EOC)...
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Cryo-EM structures of human RNA polymerase I
RNA polymerase I (Pol I) specifically synthesizes ribosomal RNA. Pol I upregulation is linked to cancer, while mutations in the Pol I machinery lead...
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Rectifying I: three point and continuous fit of the spatial autocorrelation metric, Moran’s I, to ideal form
ContextInterpreting spatial autocorrelation is complicated by differences in data type, spatial conformation, and contiguity definitions. Though...
