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Genome-scale analysis of genetic regulatory elements in Streptomyces avermitilis MA-4680 using transcript boundary information
BackgroundThe gram-positive bacterium, Streptomyces avermitilis , holds industrial importance as the producer of avermectin, a widely used...
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Disrupting FKF1 homodimerization increases FT transcript levels in the evening by enhancing CO stabilization
Key messageFKF1 dimerization is crucial for proper FT levels to fine-tune flowering time. Attenuating FKF1 homodimerization increased CO abundance...
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Altered profile of floral volatiles and lignin content by down-regulation of Caffeoyl Shikimate Esterase in Petunia
BackgroundThe floral volatile profile of Petunia x hybrida ‘Mitchell diploid’ (MD) is dominated by phenylpropanoids, many of which are derived from p ...
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Comparison of bias and resolvability in single-cell and single-transcript methods
Single-cell and single-transcript measurement methods have elevated our ability to understand and engineer biological systems. However, defining and...
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An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse
BackgroundB-cell precursor acute lymphoblastic leukemia (BCP-ALL) is a genetically heterogenous malignancy with poor prognosis in relapsed adult...
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Genetic diversity, transcript heterogeneity and allele mining of TaSKP1-6B-4 gene variants across diverse genotypes under terminal heat stress and genome wide characterization of TaSKP1 gene family from bread wheat (Triticum aestivum L.)
SKP1 (S-phase kinase protein1) is an essential regulatory component of SCF (Skp1-cullin-F-box) E3 ubiquitin ligases involved in maintenance of...
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Improving CLIP-seq data analysis by incorporating transcript information
BackgroundCurrent peak callers for identifying RNA-binding protein (RBP) binding sites from CLIP-seq data take into account genomic read profiles,...
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Identification and promoter analysis of a GA-stimulated transcript 1 gene from Jatropha curcas
Key messageOverexpression of JcGAST1 promotes plant growth but inhibits pistil development. The pyrimidine box and CGTCA motif of the JcGAST1 ...
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Evaluation of reference genes for transcript normalization in Fragaria chiloensis fruit and vegetative tissues
Quantitative real-time PCR (RT-qPCR) is used extensively in gene expression studies. For adequate comparisons, the identification and use of reliable...
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Autopolyploidization affects transcript patterns and gene targeting frequencies in Physcomitrella
Key messageIn Physcomitrella, whole-genome duplications affected the expression of about 3.7% of the protein-encoding genes, some of them relevant...
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Glycerol changes the growth and lipid profile of the marine microalga Isochrysis galbana via the regulation of photosynthetic and respiratory metabolic pathways
Isochrysis galbana is widely used in the aquaculture industry and is a potential industrial biodiesel producer. The growth of I. galbana has been...
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In Silico Characterization of a Transcript Code Based Screening of Antimicrobial Peptide from Trichogramma chilonis
Antimicrobial peptides (AMPs) from insects possess potent antimicrobial properties against various microbial related diseases. Trichogramma chilonis ...
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CRISPRi-induced transcriptional regulation of IAH1 gene and its influence on volatile compounds profile in Kluyveromyces marxianus DU3
Mezcal is a traditional Mexican distilled beverage, known for its marked organoleptic profile, which is influenced by several factors, such as the...
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Two trehalase isoforms, produced from a single transcript, regulate drought stress tolerance in Arabidopsis thaliana
Key messageAlternative translation initiation of the unique Arabidopsis trehalase gene allows for the production of two isoforms with different...
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Transcriptome-wide N6-methyladenosine methylation profile of atherosclerosis in mice
BackgroundAtherosclerosis (AS) is a critical pathological event during the progression of cardiovascular diseases. It exhibits fibrofatty lesions on...
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Gene expression profile of the develo** endosperm in durum wheat provides insight into starch biosynthesis
BackgroundDurum wheat ( Triticum turgidum subsp. durum ) is widely grown for pasta production, and more recently, is gaining additional interest due...
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Phase-shifting the circadian glucocorticoid profile induces disordered feeding behaviour by dysregulating hypothalamic neuropeptide gene expression
Here we demonstrate, in rodents, how the timing of feeding behaviour becomes disordered when circulating glucocorticoid rhythms are dissociated from...
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Protein profile analysis of Jilin white goose testicles at different stages of the laying cycle by DIA strategy
BackgroundJilin white goose is an excellent local breed in China, with a high annual egg production and laying eggs mainly from February to July each...
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Transcript profiling leads to biomarker identification for agarwood resin-loaded Aquilaria malaccensis
Key messageThe expression of terpenoid and defense response genes elevated during agarwood formation. TDFs obtained from these genes can serve as...
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Transcriptome profile of pecan scab resistant and susceptible trees from a pecan provenance collection
Pecan scab is a devastating disease that causes damage to pecan ( Carya illinoinensis (Wangenh.) K. Koch) fruit and leaves. The disease is caused by...
