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An Investigation of the Toxicity and Mechanisms of Food Additives Based on Network Toxicology and GEO Databases: A Case Study of Aspartame
This study employs network toxicology, molecular docking, and molecular dynamics simulations to assess the characteristics and potential molecular...
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Advances in testing for sample manipulation in clinical and forensic toxicology—part B: hair samples
As a continuation of part A, focusing on advances in testing for sample manipulation of urine samples in clinical and forensic toxicology, part B of...
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Advances in testing for sample manipulation in clinical and forensic toxicology - Part A: urine samples
In many countries, adherence testing is used to monitor consumption behavior or to prove abstinence. Urine and hair are most commonly used, although...
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Mass Spectrometry in Clinical Laboratory: Applications in Therapeutic Drug Monitoring and Toxicology
Mass spectrometry (MS) coupled with liquid chromatography (LC) or gas chromatography (GC) has been proven to be a powerful platform in research and...
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Hyphenated high-resolution mass spectrometry—the “all-in-one” device in analytical toxicology?
This trend article reviews papers with hyphenated high-resolution mass spectrometry (HRMS) approaches applied in analytical toxicology, particularly...
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Myricetin: The Resources, Biosynthesis, Physicochemical, Pharmacokinetic, Bioavailability, Pharmacology, and Toxicology
Myricetin is a yellow crystal of dietary flavonoid which is commonly found in plants from Anacardiaceae, Myricaceae, Pinaceae, Polygonaceae, and...
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Spectroscopy as a useful tool for the identification of changes with time in post-mortem vitreous humor for forensic toxicology purposes
Vitreous humor (VH) is an alternative biological matrix with a great advantage of longer availability for analysis due to the lack of many enzymes....
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The Magnetic Nanoparticle Actions: A Subtle Border Between Biomedicine and Toxicology
Extensive studies have been done on nanomedicine because of the increasing use of magnetic nanomaterials. The production and research of iron...
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Preparation of CuS/CuO on Decoration Graphene Oxide Nanocomposites for the Photocatalytic Degradation of Gaseous Phase Based on UV Light Irradiation, and Evaluation of Toxicology on Bacterial Cells
The present project studies the preparation of CuS/CuO on decoration of graphene oxide (GO) via the chemical rout as a photocatalyst to removal of...
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A Scaffold Free 3D Bioprinted Cartilage Model for In Vitro Toxicology
Bioprinting has emerged as a promising method for precise spatiotemporal patterning of biological materials such as living cells, genetic materials,...
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Hyperoside: A Review of Resources, Synthesis Pathways, Physicochemical Properties, Metabolism, Pharmacological Activities, Clinical Trials and Human Studies, Toxicology and Safety, Marketed Products, and Patents
Hyperoside is a natural flavonol glycoside that widely exists in many tissues (especially the aerial parts) of diverse plants. Remarkably, hyperoside...
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Growing Knowledge of Stem Cells as a Novel Experimental Model in Developmental Toxicological Studies
The increasing production and extensive application of chemicals have led to their unintended release and contamination in the environment, posing a...
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Read-Across and Quantitative Structure–Activity Relationships (QSAR) for Making Predictions and Data Gap-Filling
Read-across is originally a non-statistical grou** approach for data gap filling. The grou** of chemicals may be done based on similarities in...
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Untargeted High-Resolution Mass Spectrometry for Detection of Natural Products and Confiscated Powders and Pills
Drug testing for clinical toxicology purposes is difficult given the variety of drugs and substances that can be abused. High-resolution mass...
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Authentication of holy basil using markers relating to a toxicology-relevant compound
Holy Basil— Ocimum tenuiflorum —is one of the popular new “superfoods” thought to act as an antioxidant and to reduce stress and anxiety. However, it...
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PROTEOMAS: a workflow enabling harmonized proteomic meta-analysis and proteomic signature map**
Toxicological evaluation of substances in regulation still often relies on animal experiments. Understanding the substances’ mode-of-action is...
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Comprehensive Urine Drug Screen by Gas Chromatography-Mass Spectrometry (GC-MS)
Drug screening is an important diagnostic tool in patient management and is an indispensable part of clinical toxicology laboratory services. While...
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Future Prospects
The novel approaches of q-RA and q-RASAR appear to have much promise in quantitative predictions and data gap-filling with applications in drug...