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Multi-bioinspired Sprayable Nanotherapeutics for Tumor-Specific Focal Cancer Therapy
Chemotherapy is commonly used to treat cancer. However, insufficient retention at the target site and systemic toxicity remains critical challenges....
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Development of Efficient Strategies for Physical Stimuli-Responsive Programmable Nanotherapeutics
Stimuli-responsive nanomaterials have received lots of attention in biomedical research due to their responsiveness to different therapies under...
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Application of MOF-based nanotherapeutics in light-mediated cancer diagnosis and therapy
Light-mediated nanotherapeutics have recently emerged as promising strategies to precisely control the activation of therapeutic reagents and imaging...
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Mucoadhesive, antioxidant, and lubricant catechol-functionalized poly(phosphobetaine) as biomaterial nanotherapeutics for treating ocular dryness
Dry eye disease (DED) is associated with ocular hyperosmolarity and inflammation. The marketed topical eye drops for DED treatment often lack...
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New insights into nanotherapeutics for periodontitis: a triple concerto of antimicrobial activity, immunomodulation and periodontium regeneration
Periodontitis is a chronic inflammatory disease caused by the local microbiome and the host immune response, resulting in periodontal structure...
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Remodeling the hepatic fibrotic microenvironment with emerging nanotherapeutics: a comprehensive review
Liver fibrosis could be the last hope for treating liver cancer and remodeling of the hepatic microenvironment has emerged as a strategy to promote...
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Tea leaf-derived exosome-like nanotherapeutics retard breast tumor growth by pro-apoptosis and microbiota modulation
While several artificial nanodrugs have been approved for clinical treatment of breast tumor, their long-term applications are restricted by...
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Nanotherapeutics for Rheumatoid Arthritis Therapy
Rheumatoid arthritis is an autoimmune disease that chronically depromotes the value of life, because of the destruction of bone and cartilage,...
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High-density lipoprotein mimetic nano-therapeutics targeting monocytes and macrophages for improved cardiovascular care: a comprehensive review
The prevalence of cardiovascular diseases continues to be a challenge for global health, necessitating innovative solutions. The potential of...
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Macrophage membrane-reversibly camouflaged nanotherapeutics accelerate fracture healing by fostering MSCs recruitment and osteogenic differentiation
The fracture healing outcome is largely dependent on the quantities as well as osteogenic differentiation capacities of mesenchymal stem cells (MSCs)...
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Evaluating Nanoparticles Penetration by a New Microfluidic Hydrogel-Based Approach
Reliable predictions for the route and accumulation of nanotherapeutics in vivo are limited by the huge gap between the 2D in vitro assays used for...
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Autophagy blockade synergistically enhances nanosonosensitizer-enabled sonodynamic cancer nanotherapeutics
Ultrasound-triggered sonodynamic therapy (SDT) represents an emerging therapeutic modality for cancer treatment based on its specific feature of...
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Nanoparticle Concentration as an Important Parameter for Characterization of Dispersion and Its Applications in Biomedicine
AbstractCurrently, there are problems to standardize methods for determining the concentration of nanoparticles and creation of etalon materials for...
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Nanomedicine Applied to Inflammatory and Infectious Pulmonary Diseases
Chronic pulmonary diseases often include inflammation in the upper or lower respiratory tract causing severe/extreme discomfort. To subside...
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Nanorobotics and Nanodiagnostics in Integrative Biology and Biomedicine: A Note from the Editors
Nanosystem is structured at or below the micrometer range, made of assemblies of nanoscale components with individual dimensions ranging between 1...
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Softness enhanced macrophage-mediated therapy of inhaled apoptotic-cell-inspired nanosystems for acute lung injury
Engineered nanosystems offer a promising strategy for macrophage-targeted therapies for various diseases, and their physicochemical parameters...
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Zinc Oxide Nanoparticles in Biomedical Applications: Advances in Synthesis, Antimicrobial Properties, and Toxicity Considerations
Zinc oxide (ZnO) nanoparticles are promising nanotherapeutics used in several biomedical applications. Some of the unique features of ZnO...
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Liposomes for Delivery of Antitubercular Drugs
TB is a severe infectious disease that is yet to be eradicated and controlled. The ongoing therapy of TB (DOTS strategy) is associated with certain...