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Long-Read Metagenomics and CAZyme Discovery
Microorganisms play a primary role in regulating biogeochemical cycles and are a valuable source of enzymes that have biotechnological applications,... -
Diversity of soil fungi from sacred groves of Kerala, India revealed by comparative metagenomics analysis using illumina sequencing
The diversity, composition, and abundance of soil fungi from three sacred groves in Kerala, namely Iringole kavu of Ernakulam District, Kollakal...
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Gut microbiota of healthy Asians and their discriminative features revealed by metagenomics approach
This study is conducted to identify the microbial architecture and its functional capacity in the Asian population via the whole metagenomics...
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Metagenomics and metatranscriptomics as potential driving forces for the exploration of diversity and functions of micro-eukaryotes in soil
Micro-eukaryotes are ubiquitous and play vital roles in diverse ecological systems, yet their diversity and functions are scarcely known. This may be...
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Identification of Cutinolytic Esterase from Microplastic-Associated Microbiota Using Functional Metagenomics and Its Plastic Degrading Potential
Plastic pollution has threatened biodiversity and human health by shrinking habitats, reducing food quality, and limiting the activities of...
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Prokaryotic diversity of tropical coastal sand dunes ecosystem using metagenomics
Coastal sand dunes (CSDs), unique, stressed and hostile habitats act as a barrier between marine and terrestrial ecosystems. CSDs are stressed in...
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Evaluation of acidogenesis products’ effect on biogas production performed with metagenomics and isotopic approaches
BackgroundDuring the acetogenic step of anaerobic digestion, the products of acidogenesis are oxidized to substrates for methanogenesis: hydrogen,...
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Expanding the Database of Signal-Anchor-Release Domain Endolysins Through Metagenomics
Endolysins are bacteriophage-derived lytic enzymes with antimicrobial activity. The action of endolysins against Gram-negative bacteria remains a...
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Early response of methanogenic archaea to H2 as evaluated by metagenomics and metatranscriptomics
BackgroundThe molecular machinery of the complex microbiological cell factory of biomethane production is not fully understood. One of the process...
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Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans
BackgroundSulfate modification of N -glycans is important for several biological functions such as clearance of pituitary hormones or...
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Shotgun Metagenomic Approaches
The most recent advancements in the knowledge of sourdough ecologic meta-community come from the uncultured approach based on shotgun metagenomics... -
Machine learning for data integration in human gut microbiome
Recent studies have demonstrated that gut microbiota plays critical roles in various human diseases. High-throughput technology has been widely...
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Traditional Screening and Genome-Guided Screening of Natural Products from Actinobacteria
Since the golden era of antibiotics, around one half of the antibiotics that are available in the market were discovered. From 1960, a drop in the... -
Comparative 16S rDNA metagenomics study of two samples of cassava peel heap from Nigeria and India
The microbiology of many cassava products and the wastes generated during the processing have been reported; however, majority of these reports used...
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Cultivation and Diversity of Marine Actinomycetes: Molecular Approaches and Bioinformatics Tools
Marine habitats are still largely unexplored for their microbial diversity and ecosystem analysis. Among the marine microbial population, the... -
Genetic Engineering Strategies and Degradation of Pollutants Using Genetically Engineered Microorganisms (GEMs)
To keep the environment clean and safe, degradation of pollutants is a serious concern in the current scenario. Use of microorganisms in this regard... -
Exploring the microbial diversity and characterization of cellulase and hemicellulase genes in goat rumen: a metagenomic approach
BackgroundGoat rumen microbial communities are perceived as one of the most potential biochemical reservoirs of multi-functional enzymes, which are...
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An improved protocol for metagenomic DNA isolation from low microbial biomass alkaline hot-spring sediments and soil samples
High-quality, humic-acid-free pure DNA is a prerequisite for functional and sequence-based approaches of metagenomics. In the present investigation,...
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Functional mining of novel terpene synthases from metagenomes
BackgroundTerpenes are one of the most diverse and abundant classes of natural biomolecules, collectively enabling a variety of therapeutic, energy,...
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Derivation of a novel antimicrobial peptide from the Red Sea Brine Pools modified to enhance its anticancer activity against U2OS cells
Cancer associated drug resistance is a major cause for cancer aggravation, particularly as conventional therapies have presented limited efficiency,...