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Development of target-based cell membrane affinity ultrafiltration technology for a simplified approach to discovering potential bioactive compounds in natural products
Target-based drug discovery technology based on cell membrane targets has gained significant traction and has been steadily advancing. However,...
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Cellulose-based nanofiber membrane functionalized with dye affinity ligand for purification of malate dehydrogenase from Saccharomyces cerevisiae
Cellulose-based nanofibers are a versatile material with broad applications, including wound-healing/dressing biomaterials, food packing, water...
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Affinity-based electrochemical sensors for biomolecular detection in whole blood
The detection and/or quantification of biomarkers in blood is important for the early detection, diagnosis, and treatment of a variety of diseases...
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Affinity-based isolation of extracellular vesicles and the effects on downstream molecular analysis
Extracellular vesicles (EVs) are transport vesicles with diameters ranging from 30 to 1000 nm, secreted by cells in both physiological and...
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Aptamer-based Membrane Protein Analysis and Molecular Diagnostics
Membrane proteins are vital components of the cell membrane and play crucial roles in various cellular activities. Analysis of membrane proteins is...
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Microbead-based extracorporeal immuno-affinity virus capture: a feasibility study to address the SARS-CoV-2 pandemic
In this paper, we report on the utilization of micro-technology based tools to fight viral infections. Inspired by various hemoperfusion and...
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Pilot investigation of magnetic nanoparticle–based immobilized metal affinity chromatography for efficient enrichment of phosphoproteoforms for mass spectrometry–based top-down proteomics
Protein phosphorylation is a vital and common post-translational modification (PTM) in cells, modulating various biological processes and diseases....
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Affinity-based and in a single step purification of recombinant horseradish peroxidase A2A isoenzyme produced by Pichia pastoris
Horseradish peroxidase (HRP) is an oxidoreductase enzyme and oxidizes various inorganic and organic compounds. It has wide application areas such as...
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Preparation and properties of boron affinity molecularly imprinted mesoporous polymers based on Mn-doped ZnS quantum dots
Sialic acid (SA), known as N -acetyl neuraminic acid, is a natural 9-carbomonosaccharide derivative. SA has been widely applied in the early diagnosis...
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Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions
Macrocycle peptides are promising constructs for imaging and inhibiting extracellular, and cell membrane proteins, but their use for targeting...
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Microbial fabrication of cellulose nanofiber-based ultrafiltration membrane: a sustainable strategy for membrane manufacture
Develo** a sustainable separation membrane is imperative due to the growing environmental pollution caused by petrochemical-based polymers....
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Strategies for the Purification of Membrane Proteins
Membrane proteins account for approximately 30% of the coding regions of all sequenced genomes, and they play crucial roles in many fundamental cell... -
Stable and easily detachable cellulose-based membrane system inspired by water hyacinth for efficient heavy metals removal from water
A rapid extracted and concentrated system engineered by green polymers is attractive but there is still a challenge with respect to both materials...
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Transient Co-expression of Membrane Protein Complexes in Mammalian Cells
Membrane proteins are essential components of biological membranes with key roles in cellular processes such as nutrient transport, cell... -
Arsenic water decontamination by a bioinspired As-sequestering porous membrane
Arsenic water contamination is a major issue worldwide, particularly in regions where groundwater is the primary source of drinking and irrigation...
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Recent Trends in Membrane Processing of Whey
Whey is a liquid fraction derived by separating the coagulum from milk, skim milk or cream and it is a valuable by-product of cheese manufacturing.... -
Enhanced permeability of cellulose acetate ultrafiltration membrane by incorporation of cellulose graft copolymer
In this research, a series of cellulose acetate (CA)-based blend ultrafiltration (UF) membranes bearing poly(ε-decalactone) (PDL)-grafted cellulose...
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MXene supported biomimetic bilayer lipid membrane biosensor for zeptomole detection of BRCA1 gene
A biomimetic bilayer lipid membrane supported MXene based biosensor is reported for electrochemical hybridization detection of the most prevalent and...
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Monitoring of Cell Membrane Microenvironment Based on DNA Nanodevices
The cell membrane is a critical barrier for cellular homeostasis, integral to signaling and intercellular communication, and vital for understanding...