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Drug Discovery Methods for Studying Brain Drug Delivery and Distribution
Methods used in drug discovery laboratories for assessing the delivery of small molecules to the brain have changed significantly in recent years.... -
Biostatistical Investigation Using Docking Mechanism and Its Database to Investigate Drug Design, Drug Discovery, Drug Metabolism and Prediction Via Drug–Drug Interactions
Molecular docking is an important tool for structure-based drug design and is being widely used to study molecular interactions with proteins at... -
Drug Delivery Using Carbon Nanomaterials
Carbon nanomaterials (CNs) possess unique physical, chemical, and physiological properties that make them highly valuable as carriers for... -
Smart Drug Nanoparticles from Microorganisms and Drug Delivery
Smart drug nanoparticles are a type of drug delivery system that uses nanomaterials, typically made of biocompatible materials such as lipids or... -
Biobased Nanomaterials in Drug Delivery
Biobased nanomaterials have emerged as a pivotal element in modern drug delivery, garnering substantial attention within scientific research. These... -
Drug Delivery to the Brain Physiological Concepts, Methodologies and Approaches
The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of... -
Nanostructured Devices Based on Block Copolymer Assemblies for Drug Delivery: Designing Structures for Enhanced Drug Function
Block copolymers spontaneously assemble into nanoscaled polymeric micelles, which have significant potential as drug carriers. Following much work... -
Drug Delivery Systems for Cartilage
A dense network of extracellular matrix and lack of vascularization pose a major challenge in the delivery of therapeutics in the cartilage. Recent... -
Nanofluidic Technologies for Drug Screening and Drug Delivery
Recently, nanofluidics exploiting 10–1000 nm spaces has developed and suggested a potential of novel analytical methods for pharmaceutical studies... -
Databases for Drug Discovery and Development
Computational drug design and discovery have taken center stage attention during the time of COVID-19. The science community acknowledges the... -
Controlled Drug Delivery System
This comprehensive chapter delves into the world of controlled drug delivery systems, exploring their fundamental aspects, advancements, and future... -
Drug Delivery Systems and Cardiovascular Disease
Clinically, with the treatment of cardiovascular disease in addition to surgery and interventional therapy, drug therapy is also a common means. With... -
PermuteDDS: a permutable feature fusion network for drug-drug synergy prediction
MotivationDrug combination therapies have shown promise in clinical cancer treatments. However, it is hard to experimentally identify all drug...
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Functional Biomaterials for Targeted Drug Delivery Applications
Targeted drug delivery approaches have been widely employed to regulate the absorption and biodistribution of small molecules and biologics at the... -
Molecular Docking in Drug Designing and Metabolism
The traditional drug discovery methods and analysis of drug target interactions and physiological responses through biological experiments are... -
Investigation of Factors Affecting Particle Size Distribution and Sustained Release of a Water-Soluble Drug from Cellulose Derivatives Microspheres
Microspheres loaded by 2-aminopyrimidine (2-AP) and based on cellulose derivatives as polymeric matrices: ethylcellulose (EC) and cellulose acetate...
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Nanosuspension – A Novel Drug Delivery System via Nose-to-Brain Drug Delivery
NanosuspensionNanosuspensions administration via the nasal routeNasal route of administration appears to be an effective pathway of... -
Drug Delivery Systems for Intervertebral Disc
Intervertebral disc (IVD) degeneration is one of the most common degenerative joint diseases that cause pain and disability in adults. It is also a... -
Dendrimers-Based Drug Delivery in Tuberculosis
Tuberculosis (TB) is a disease caused by a microorganism (Mycobacterium tuberculosis) which invades the lungs and initiates the disease. Currently,... -
Alginate-Based Hydrogels as Drug Carriers
Alginate hydrogels have appeared as a highly promising category of biocompatible medical devices that can be implanted, injected, or implemented on...