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Highly sensitive and novel dual-emission fluorescence nanosensor utilizing hybrid carbon dots–quantum dots for ratiometric determination of chlorpromazine
Herein, a ratiometric fluorimetric nanosensor is introduced for the sensitive and selective analysis of chlorpromazine (CPZ) via employing...
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Determination of chlorpromazine, levomepromazine, and promethazine by sequential injection analysis with VIS spectrometric or spectrofluorimetric detection
Automatic sequential injection analysis (SIA) with spectrometric or spectrofluorimetric detection is presented for the determination of three...
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Ultrasensitive SERS substrate for label-free therapeutic drug monitoring of chlorpromazine hydrochloride and aminophylline in human serum
Surface-enhanced Raman spectroscopy (SERS) has been widely used in the field of therapeutic drug monitoring (TDM) because of its powerful...
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Design of sonochemical assisted synthesis of Zr-MOF/g-C3N4-modified electrode for ultrasensitive detection of antipsychotic drug chlorpromazine from biological samples
The rapid fabrication is described of binary electrocatalyst based on a highly porous metal–organic framework with zirconium metal core (Zr-MOF)...
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A photochemical approach to anchor Au NPs on MXene as a prominent SERS substrate for ultrasensitive detection of chlorpromazine
As a novel two-dimensional (2D) material, metal carbide (MXene) has been identified as a hotspot research topic in the field of surface-enhanced...
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Immobilized Artificial Membrane Chromatography Using Acetonitrile-Rich Mobile Phase for Comparison of Retention Properties Between Phospholipidosis-Inducing and Non-inducing Basic Drugs
Immobilized artificial membrane chromatography has been reported providing a rough estimation of phospholipidosis induction risk of drugs....
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Synthesis of La3+/Co3O4 Nanoflowers for Sensitive Detection of Chlorpromazine
In this study, a sensitive electrochemical sensor for chlorpromazine was established based on La 3+ /Co 3 O 4 nanoflower. The La 3+ /Co 3 O 4 nanoflower...
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Production and certification of BOTS-1: bovine muscle–certified reference material for incurred veterinary drug residues
A freeze-dried bovine muscle–certified reference material (CRM), known as BOTS-1 (DOI: https://doi.org/10.4224/crm.2018.bots-1 ), containing incurred...
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Functionalization of a carbon nanofiber with a tetrasulfonatophenyl ruthenium(II)porphine complex for real-time amperometric sensing of chlorpromazine
A carbon nanofiber functionalized with ruthenium(II)-tetrasulfonato phenyl porphine (CNF/Ru-TSPP) is shown to be viable sensor for amperometric...
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Determination of Sedatives and β-Blocker Residues in Bovine, Swine, and Equine Kidney by Liquid Chromatography Coupled to Tandem Mass Spectrometry
Sedatives and β-blockers are frequently utilized to mitigate stress in the transport of livestock, specifically pigs, with the goal of avoiding...
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Screening of Potential Non-Azole Inhibitors of Lanosterol 14-Alpha Demethylase (CYP51) of the Сandida Fungi
Opportunistic fungi of the genus Candida are currently considered as the major causative agents of mycoses, which are characterized by an especially...
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Development of a simultaneous LC–MS/MS analytical method for plasma: 16 antipsychotics approved in Japan and 4 drug metabolites
The increased risk of adverse drug reactions due to the concomitant use of antipsychotics is problematic in the treatment of schizophrenia....
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Preparation and Evaluation of Molecularly Imprinted Polymers for Promazine and Chlorpromazine by Multi-step Swelling and Polymerization: the Application for the Determination of Promazine in Rat Serum by Column-switching LC
Molecularly imprinted polymers (MIP s ) for promazine (PZ) and chlorpromazine (CPZ), MIP PZ and MIP CPZ , were prepared by multi-step swelling and...
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Synthesis of azo-linked covalent organic polymers for pipette tip solid-phase extraction of sedative residues from animal tissues samples
Azo-linked covalent organic polymers (ACOPs) were synthesized by a simple azo reaction, with 2,2ʹ-bis(trifluoromethyl)benzidine and...
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A Dynamic Covalent Bonding-based Nanoplatform for Intracellular Co-Delivery of Protein Drugs and Chemotherapeutics with Enhanced Anti-Cancer Effect
Efficient intracellular delivery of protein drugs is critical for protein therapy. The combination of protein drugs with chemotherapeutics represents...
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Fabrication of a novel tantalum boride/vanadium carbide modified screen-printed carbon electrode for voltammetric determination of pimonidazole in bio-fluids
For the first time, a tumour hypoxia marker detection has been developed using two-dimensional layered composite modified electrodes in biological...
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Influence of Antidepressant Drug on the Conductivity of Cationic Surfactant
AbstractIn this study, the electrical conductivity of the antidepressant drug—nortriptyline hydrochloride and conventional...
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OCTN2- and ATB0,+-targeted nanoemulsions for improving ocular drug delivery
Traditional eye drops are administered via topical instillation. However, frequent dosing is needed due to their relatively rapid precorneal removal...
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B- and N-doped carbon dots by one-step microwave hydrothermal synthesis: tracking yeast status and imaging mechanism
BackgroundCarbon dots (CDs) are widely used in cell imaging due to their excellent optical properties, biocompatibility and low toxicity. At present,...
