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Determination and Quantification of Cetirizine Dihydrochloride in Pharmaceutical Formulations and Biological Fluids Through Fluorescence Quenching of Eosin Y: Application to Content Uniformity Test
AbstractA simple, fast, sensitive, cost-effective, and well-proven spectrofluorimetric method has been developed for the quantification of cetirizine...
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Solubility Measurement, Model Correlation, and Solvent Effect Analysis of Spectinomycin Dihydrochloride Pentahydrate in Three Binary Solvents
The solubility data of spectinomycin dihydrochloride pentahydrate (SDP) in three binary solvents were determined over a temperature range of...
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Comparative study of four innovative earth-friendly platforms for rapid analysis of daclatasvir dihydrochloride: Application on different matrices
BackgroundDaclatasvir dihydrochloride has important roles not only in the management of COVID-19 pandemic symptoms but also in the treatment of...
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Determination of Cetirizine Dihydrochloride in Tablets by Flow Injection Technique Using [Ag(HIO6)2]5−–H2SO4 Chemiluminescence System
AbstractA simple trivalent silver complex ([Ag(HIO 6 ) 2 ] 5− ) and sulfuric acid chemiluminescence ( CL ) reaction is established for cetirizine...
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Preparation and characterization of halloysite nanotubes containing hydrogels for controlled release drug delivery of cetirizine dihydrochloride
AbstractThe objective of the present study was to improve the mucosal adherence of nasal formulations through the application of swellable,...
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Harnessing Heterocycles: Fine-Tuning Furan-Pyridine Amidines for Precision Anticancer Therapy
AbstractTwo new dichlorophenylfurylnicotinamidine regioisomers and were prepared from the corresponding dichlorophenylfurylnicotinonitriles when...
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Particular thermal behavior of 2,2′-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride using DSC and STA
2,2′-Azobis[2-(2-imidazolin-2-yl) propane] dihydrochloride (AIBI) is a class of initiators that share water-soluble features, which was widely...
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Stability evaluation and kinetic study for the atypical antidepressant opipramol
Opipramol is an active pharmaceutical ingredient used as an antidepressant and anxiolytic, being formulated as a dihydrochloride salt, usually in...
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Combined experimental and computational investigation of a Schiff base derived from N-(1-naphthyl)ethylenediamine for fluoride recognition
The Bratton–Marshall reagent, a free base of N -(1-naphthyl)ethylenediamine dihydrochloride (NEDA 2+ .2Cl − ), is used to analyse arylamine type of drugs...
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Synthesis and antibacterial activity of new bis-quaternary ammonium compounds based on polyhydric alcohol
The synthesis of bis-quaternary ammonium compounds based on a polyhydric alcohol, 2,3-bis(hydroxymethyl)butane-1,4-diol, and pyridine was...
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An Oxygen-Independent Photodynamic Therapy Nanoplatform for Combating Anaerobic Infection
Anaerobic bacteria infections remain a major threat to humans. Oxidative stress mediated by photodynamic therapy (PDT) has shown great potential in...
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Synthesis and Biological Properties of N-Acylaminoacryloylhistamines and the Corresponding 4-Arylideneimidazol-5(4H)-ones
AbstractThe reaction of unsaturated 4-arylidenoxazol-5(4 H )-ones with 2-(1 H -imidazol-4-yl)ethan-1-amine dihydrochloride was used to synthesize...
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Detection of 2,2′-Azobis(2-amidinopropane) Dihydrochloride in Polyvinylpyrrolidone by Capillary Electrophoresis with Field-Amplified Sample Injection
A sensitive method was developed for detecting 2,2′-azobis(2-amidinopropane) dihydrochloride in polyvinylpyrrolidone by capillary electrophoresis...
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Thermal hazard evaluation conjoined with product analysis of two water-soluble azo compounds
Azo compounds are widely used in polymerization as an initiator for chain polymerization reactions. Although they have excellent initiating...
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Factor Optimization Study to Develop and Validate a Reversed-Phase Thin-Layer Chromatography Method for the Determination of Trimetazidine Dihydrochloride and Its Reported Impurities in Pharmaceuticals
A validated reversed-phase thin-layer chromatography (RP-TLC)—densitometry method was developed and optimized for the determination of trimetazidine...
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Synthesis and characterization of poly(vinyl sulfonic acid) in different pH values
Vinyl sulfonic acid (VSA) monomer at various pH values was polymerized by using a special radical initiator 2,2′-azobis(2-methylpropanediamine)...
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3-Aminophenylboronic acid–functionalized molybdenum disulfide quantum dots for fluorescent determination of hypochlorite
A simple method is reported for hypochlorite determination based on fluorescence 3-aminophenylboronic acid–functionalized molybdenum disulfide...
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Four chemometric models enhanced by Latin hypercube sampling design for quantification of anti-COVID drugs: sustainability profiling through multiple greenness, carbon footprint, blueness, and whiteness metrics
Montelukast sodium (MLK) and Levocetirizine dihydrochloride (LCZ) are widely prescribed medications with promising therapeutic potential against...
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Asymmetric Crosslinked Polyacrylamide/Natural Rubber Semi-IPN Hydrogel for Application of Methyl Orange Dye Removal: Combined Experimental and DFT Study
This study presents a combined experimental and density functional theory (DFT) investigation into the synthesis and characterization of the...
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Synthesis and characterization of (allylamine hydrochloride-vinyl sulfonic acid) copolymer and determination of monomer reactivity ratios
Polyelectrolytes show complexation by the other polymers having opposite charges. Allyamine (AlAm) is a cationic monomer, and vinyl sulfonic acid...