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Design, Synthesis, and Biological Evaluation of Fluoroquinolones Linked to 4-Thiazolidinone Moieties as Potent Antimicrobial Agents: Docking Analysis
AbstractA series of novel fluoroquinolone thiazolidinone derivatives were synthesized and evaluated for their biological activity. All the newly...
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Antibiotics Immunoassay in Food
Antibiotics are a class of secondary metabolites produced by microorganisms (including bacteria, fungi and actinomyces) or advanced animals and... -
NDM-5-carrying Klebsiella pneumoniae ST437 belonging to high-risk clonal complex (CC11) from an urban river in eastern India
In this study, we described the carbapenem bla NDM-5 -carrying extensive drug-resistant (XDR) K. pneumoniae ST437 from an urban river water Kathajodi...
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Simultaneous determination of multiclass antibiotics and their metabolites in four types of field-grown vegetables
The developed method was evaluated for the determination of 10 antibiotics belonging to four chemical classes (fluoroquinolones, sulfonamides,...
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One-step hydrothermal preparation of biomass-derived carbon dots as fluorescent probes for the detection of enrofloxacin in aquatic products
Enrofloxacin (ENR) residue is harmful to humans and the ecosystem. Therefore, it is necessary to develop a method for the detection of ENR residues...
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Development of a simple and sensitive method for the determination of virginiamycin M1 antibiotic by capillary electrophoresis
Virginiamycin antibiotic is used in Mexico for animal growth promotion but has been banned in Europe due to risk of resistance development. Giving...
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Solid-Phase-Fluorimetric Determination of Quinolones in Medicinal Preparations on Cellulose Paper and in a Thin Silica Layer Using a Smartphone
AbstractA simple and an available method is proposed for the determination of quinolone antibiotics using solid-phase fluorescence digital...
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Metals to combat antimicrobial resistance
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific metal may be essential for survival yet toxic in certain...
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Electrochemical Sensor Based on Nitrogen Doped Porous Reduced Graphene Oxide to Detection of Ciprofloxacin in Pharmaceutical Samples
AbstractFluoroquinolone ciprofloxacin (Cip) is an antibiotic used to treat some bacterial infections such as bone, joint, respiratory tract, skin,...
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Metagenomic investigation of the seasonal distribution of bacterial community and antibiotic-resistant genes in Day River Downstream, Ninh Binh, Vietnam
In this study, we use high-throughput sequencing-based metagenomic methods to investigate the differences in seasonal structures of the bacterial...
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Nanobiotics against antimicrobial resistance: harnessing the power of nanoscale materials and technologies
Given the spasmodic increment in antimicrobial resistance (AMR), world is on the verge of “post-antibiotic era”. It is anticipated that current...
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Micronization of Levofloxacin Hemihydrate Using Supercritical Trifluoromethane
AbstractMicronization of the pharmaceutical substance levofloxacin hemihydrate (LFC) was studied by the RESS method with trifluoromethane (CHF 3 ) as...
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Use of Total Fluorescence Spectroscopy for the Highly Sensitive Simultaneous Determination of Fluoroquinolones in Rabbit Plasma
AbstractA method for the quantification of a mixture of fluorescent antibiotics with broad, highly overlapped excitation and emission spectra is...
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Adsorptive removal of levofloxacin and antibiotic resistance genes from hospital wastewater by nano-zero-valent iron and nano-copper using kinetic studies and response surface methodology
In the twenty-first century, water contamination with pharmaceutical residues is becoming a global phenomenon and a threat. Antibiotic residues and...
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A chemometric approach based on Box–Behnken and response surface methodology for design and optimization of ciprofloxacin adsorption from water
The overuse of antibiotics, e.g., ciprofloxacin in aquafarming, and therapy activities have increasingly raised their presence in water sources,...
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Wastewater-Based Epidemiology (WBE): An Emerging Nexus Between Environment and Human Health
Water, an integral component of life on earth, is being hampered or exploited to a great extent owing to both natural and anthropogenic activities.... -
GyrB inhibitors as potential antibacterial agents: a review
Bacterial resistance to antibiotics is rising to dangerously high levels globally making it one of the most urgent public health problems. Hence,...