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Role of Extremophiles in the Treatment of Industrial Waste, Pharmaceuticals, and Personal Care Products
Industrial waste, pharmaceutical waste, and personal care products’ prevalence in soil and water bodies are of emerging concern at present. Moreover,...
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Powering mesoporous silica nanoparticles into bioactive nanoplatforms for antibacterial therapies: strategies and challenges
Bacterial infection has been a major threat to worldwide human health, in particular with the ever-increasing level of antimicrobial resistance....
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Fluorinated 1,3-benzothiazin-4-ones containing fluoroquinolone fragment
We have developed an efficient synthetic approach to potential antibacterial agents with double mechanism of action through the combination of...
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Dicationic Imidazolium Surfactants with a Hydroxyl Substituent in the Spacer Fragment
AbstractDicationic imidazolium surfactants of the 1,1′-(2-hydroxypropan-1,3-diyl)bis(3-alkyl-1 H -imidazol-3-ylium)chloride series with a variable...
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Oxidized gum arabic cross-linked pectin/O-carboxymethyl chitosan: An antibiotic adsorbent hydrogel
The current work investigated the synthesis possibility of oxidized gum arabic cross-linked pectin/O-carboxymethyl chitosan hydrogels (OGA-Pc-O-CMCS)...
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Atom-efficient synthesis of hybrid molecules combining fragments of triazolopyrimidines and 3-ethoxycarbonyl-1-ethyl-6-fluoroquinolin-4(1H)-one through 1,2,3-triazole linker
An atom-efficient method toward hybrid molecules via azide-alkyne cycloaddition of 7-azido-3-ethoxycarbonyl-1-ethyl-6-fluoroquinolin-4(1 H )-one and...
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Design, synthesis and in vitro bioactivity of mixed ligand Ru(II) complexes bearing the fluoroquinolone antibacterial agents
Mixed ligand Ru(II) phenanthroline complexes of the type [Ru(1,10- phen ) 2 Flq]ClO 4 ( RPFlq-1-3 ) and “piano-stool”-type Ru(II) arene complexes [Ru( η 6 - p -cy...
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In Silico Approach for Phytocompound-Based Drug Designing to Fight Efflux Pump-Mediated Multidrug-Resistant Mycobacterium tuberculosis
Tuberculosis (TB), caused by the bacteria Mycobacterium tuberculosis , is one of the principal causes of death in the world despite the existence of a...
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Enhanced Antibacterial Activity of Highly Biocompatible Polymeric Core–Shell Levofloxacin Gold Nanocomposite Formulation Against Pseudomonas aeruginosa
Using natural and synthetic polymers as the components for the core–shell nanocomposite preparation has received recent attention in biomedicine due...
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Determination of Norfloxacin by Sensitized Terbium Fluorescence in the Presence of Silver Nanoparticles and Surfactant Micelles
AbstractThe effect of silver nanoparticles and surfactant micelles on their joint presence on the intensity of the sensitized fluorescence of the...
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Key genes of electron transfer, the nitrogen cycle and tetracycline removal in bioelectrochemical systems
BackgroundSoil microbial fuel cells (MFCs) can remove antibiotics and antibiotic resistance genes (ARGs) simultaneously, but their removal mechanism...
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An insight into the photocatalytic degradation of the antibiotic rifampicin by titanium dioxide nanoparticles in aqueous solution under UV light irradiation
Photocatalytic degradation of antibiotic rifampicin (RIF) in aqueous solution, employing 100-nm sized anatase TiO 2 nanoparticles (NPs) as a catalyst,...
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Ciprofloxacin Metal Complexes–Silica Nanoparticles: Characterization, Spectroscopic Study, DNA Interaction and Biological Activity
Ciprofloxacin (CIPH) was classified as one of the most effective quinolone antibiotics, which is commonly used to cure a wide range of infections...
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CO2-plasma surface treatment of graphite sheet electrodes for detection of chloramphenicol, ciprofloxacin and sulphanilamide
Graphite sheet (GS) electrodes are flexible and versatile substrates for sensing electrochemical; however, their use has been limited to incorporate...
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Electrochemical Properties, Antimicrobial Activity and Photocatalytic Performance of Cerium-Iron Oxide Nanoparticles
AbstractCerium doped iron oxide nano-structured particles were synthesized by the hydrothermal method, which is a simple and inexpensive. The...
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Drug Delivery to Diseases Caused by E. coli Infection
The Escherichia coli are one of the most common facultative anaerobe in the intestinal tract of humans and many other endothermic species. Mostly,...
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Molecular Analysis of Pseudomonas aeruginosa Isolates with Mutant gyrA Gene and Development of a New Ciprofloxacin Derivative for Antimicrobial Therapy
This study focuses on the prevalence of Pseudomonas aeruginosa in various medical specimens. In addition, the investigates of this research shows the...
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Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus
Membrane protein efflux pumps confer antibiotic resistance by extruding structurally distinct compounds and lowering their intracellular...
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NDM-5-carrying Klebsiella pneumoniae ST437 belonging to high-risk clonal complex (CC11) from an urban river in eastern India
In this study, we described the carbapenem bla NDM-5 -carrying extensive drug-resistant (XDR) K. pneumoniae ST437 from an urban river water Kathajodi...
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Design, Synthesis, and Biological Evaluation of Fluoroquinolones Linked to 4-Thiazolidinone Moieties as Potent Antimicrobial Agents: Docking Analysis
AbstractA series of novel fluoroquinolone thiazolidinone derivatives were synthesized and evaluated for their biological activity. All the newly...
